Search Results - "D'OFFIZI, Gianpiero"

Late Relapse and Reinfection in HCV Patients Treated with Direct-Acting Antiviral (DAA) Drugs by Minosse, Claudia, Gruber, Cesare E. M., Rueca, Martina, Taibi, Chiara, Zaccarelli, Mauro, Grilli, Elisabetta, Montalbano, Marzia, Capobianchi, Maria R., Antinori, Andrea, D’Offizi, Gianpiero, McPhee, Fiona, Garbuglia, Anna Rosa

“…The risk of hepatitis C virus (HCV) recurrence after direct-acting antiviral (DAA) treatment is <0.5%. However, the distinction between HCV RNA late relapse…”
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Anti-HEV IgG Avidity Testing: Utility for Diagnosing Acute and Resolved Genotype 3 Infections by Minosse, Claudia, Lapa, Daniele, Coppola, Antonio, Rapagna, Federica, D'Offizi, Gianpiero, Taibi, Chiara, Lionetti, Raffaella, Capobianchi, Maria Rosaria, McPhee, Fiona, Garbuglia, Anna Rosa

“…European Association of the Study of the Liver (EASL) guidelines specify HEV RNA, as well as anti-HEV IgG and IgM as positive markers for acute HEV infection…”
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Hepatic Failure in COVID-19: Is Iron Overload the Dangerous Trigger? by Del Nonno, Franca, Nardacci, Roberta, Colombo, Daniele, Visco-Comandini, Ubaldo, Cicalini, Stefania, Antinori, Andrea, Marchioni, Luisa, D’Offizi, Gianpiero, Piacentini, Mauro, Falasca, Laura

“…Liver injury in COVID-19 patients has progressively emerged, even in those without a history of liver disease, yet the mechanism of liver pathogenicity is…”
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Clinical Relevance of Torque Teno Virus (TTV) in HIV/HCV Coinfected and HCV Monoinfected Patients Treated with Direct-Acting Antiviral Therapy by Lapa, Daniele, Del Porto, Paola, Minosse, Claudia, D’Offizi, Gianpiero, Antinori, Andrea, Capobianchi, Maria Rosaria, Visco-Comandini, Ubaldo, McPhee, Fiona, Garbuglia, Anna Rosa, Zaccarelli, Mauro

“…Torque Teno virus (TTV) is a ubiquitous virus that causes chronic infection in humans with unknown clinical consequences. Here, we investigated the influence…”
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Incidence of Pneumothorax and Pneumomediastinum in 497 COVID-19 Patients with Moderate–Severe ARDS over a Year of the Pandemic: An Observational Study in an Italian Third Level COVID-19 Hospital by Tetaj, Nardi, Garotto, Gabriele, Albarello, Fabrizio, Mastrobattista, Annelisa, Maritti, Micaela, Stazi, Giulia Valeria, Marini, Maria Cristina, Caravella, Ilaria, Macchione, Manuela, De Angelis, Giada, Busso, Donatella, Di Lorenzo, Rachele, Scarcia, Silvana, Farina, Anna, Centanni, Daniele, Vargas, Joel, Savino, Martina, Carucci, Alessandro, Antinori, Andrea, Palmieri, Fabrizio, D’Offizi, Gianpiero, Ianniello, Stefania, Taglietti, Fabrizio, Campioni, Paolo, Vaia, Francesco, Nicastri, Emanuele, Girardi, Enrico, Marchioni, Luisa

“…(1) Background: COVID-19 is a novel cause of acute respiratory distress syndrome (ARDS). Indeed, with the increase of ARDS cases due to the COVID-19 pandemic,…”
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Lymphofollicular lesions associated with monkeypox (Mpox) virus proctitis by Mazzotta, Valentina, Scorzolini, Laura, Falasca, Laura, Lionetti, Raffaella, Aguglia, Camilla, Kontogiannis, Dimitra, Colombo, Daniele, Colavita, Francesca, De Palo, Maria Grazia, Carletti, Fabrizio, Mondi, Annalisa, Pinnetti, Carmela, Maffongelli, Gaetano, Garbuglia, Anna Rosa, Baldini, Francesco, Corpolongo, Angela, Maggi, Fabrizio, D'Offizi, Gianpiero, Girardi, Enrico, Vaia, Francesco, Nicastri, Emanuele, Del Nonno, Franca, Antinori, Andrea

“…•Monkeypox (Mpox) virus has been recently recognized as a cause of proctitis in men who have sex with men.•Mpox proctitis may lead to hospitalization for…”
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Dynamics of HCV genotype 4 resistance-associated variants during virologic escape with pIFN/RBV + daclatasvir: A case study using ultra deep pyrosequencing by Bartolini, Barbara, Lionetti, Raffaella, Giombini, Emanuela, Sias, Catia, Taibi, Chiara, Montalbano, Marzia, D’Offizi, Gianpiero, McPhee, Fiona, Hughes, Eric A, Zhou, Nannan, Ippolito, Giuseppe, Garbuglia, Anna Rosa, Capobianchi, Maria R

“…Highlights • HCV GT4 patients receiving daclatasvir: a case study. • Ultra-deep sequencing of HCV NS5A region. • NS5A diversity at baseline was not…”
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Outcomes and Timing of Bedside Percutaneous Tracheostomy of COVID-19 Patients over a Year in the Intensive Care Unit by Tetaj, Nardi, Maritti, Micaela, Stazi, Giulia, Marini, Maria, Centanni, Daniele, Garotto, Gabriele, Caravella, Ilaria, Dantimi, Cristina, Fusetti, Matteo, Santagata, Carmen, Macchione, Manuela, De Angelis, Giada, Giansante, Filippo, Busso, Donatella, Di Lorenzo, Rachele, Scarcia, Silvana, Carucci, Alessandro, Cabas, Ricardo, Gaviano, Ilaria, Petrosillo, Nicola, Antinori, Andrea, Palmieri, Fabrizio, D’Offizi, Gianpiero, Ianniello, Stefania, Campioni, Paolo, Pugliese, Francesco, Vaia, Francesco, Nicastri, Emanuele, Ippolito, Giuseppe, Marchioni, Luisa

“…Background: The benefits and timing of percutaneous dilatational tracheostomy (PDT) in Intensive Care Unit (ICU) COVID-19 patients are still controversial. PDT…”
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Clinical Characteristics of Acute Hepatitis E and Their Correlation with HEV Genotype 3 Subtypes in Italy by Minosse, Claudia, Biliotti, Elisa, Lapa, Daniele, Rianda, Alessia, Marchili, Mauro, Luzzitelli, Ilaria, Capobianchi, Maria Rosaria, McPhee, Fiona, Garbuglia, Anna Rosa, D’Offizi, Gianpiero

“…Genotype 3 (GT3) is responsible for most European autochthonous hepatitis E virus (HEV) infections. This study analyzed circulating genotypes and GT3 subtypes…”
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Massively parallel pyrosequencing highlights minority variants in the HIV-1 env quasispecies deriving from lymphomonocyte sub-populations by Rozera, Gabriella, Abbate, Isabella, Bruselles, Alessandro, Vlassi, Crhysoula, D'Offizi, Gianpiero, Narciso, Pasquale, Chillemi, Giovanni, Prosperi, Mattia, Ippolito, Giuseppe, Capobianchi, Maria R

“…Virus-associated cell membrane proteins acquired by HIV-1 during budding may give information on the cellular source of circulating virions. In the present…”
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Phylogenetic and Phylodynamic Analyses of HCV Strains Circulating among Patients Using Injectable Drugs in Central Italy by Minosse, Claudia, Salichos, Leonidas, Taibi, Chiara, Luzzitelli, Ilaria, Nardozi, Daniela, Capobianchi, Maria Rosaria, D’Offizi, Gianpiero, McPhee, Fiona, Garbuglia, Anna Rosa

“…Approximately 71 million people worldwide are infected with the hepatitis C virus (HCV). Injectable drug use represents the most common route of transmission…”
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TREATMENT OF HEPATITIS C VIRUS INFECTION IN ITALY: A CONSENSUS REPORT FROM AN EXPERT PANEL by Viganò, M, Perno, C.F, Craxì, A

“…Abstract Hepatitis C virus (HCV) infection remains one of the main causes of chronic liver disease worldwide. The advent of direct-acting antivirals (DAAs) has…”
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Postmortem Findings in Italian Patients With COVID-19: A Descriptive Full Autopsy Study of Cases With and Without Comorbidities by Falasca, Laura, Nardacci, Roberta, Colombo, Daniele, Lalle, Eleonora, Di Caro, Antonino, Nicastri, Emanuele, Antinori, Andrea, Petrosillo, Nicola, Marchioni, Luisa, Biava, Gianluigi, D’Offizi, Gianpiero, Palmieri, Fabrizio, Goletti, Delia, Zumla, Alimuddin, Ippolito, Giuseppe, Piacentini, Mauro, Del Nonno, Franca

“…Abstract Background Descriptions of the pathological features of coronavirus disease-2019 (COVID-19) caused by the novel zoonotic pathogen severe acute…”
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Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution by Baiocchini, Andrea, Montaldo, Claudia, Conigliaro, Alice, Grimaldi, Alessio, Correani, Virginia, Mura, Francesco, Ciccosanti, Fabiola, Rotiroti, Nicolina, Brenna, Alessia, Montalbano, Marzia, D'Offizi, Gianpiero, Capobianchi, Maria Rosaria, Alessandro, Riccardo, Piacentini, Mauro, Schininà, Maria Eugenia, Maras, Bruno, Del Nonno, Franca, Tripodi, Marco, Mancone, Carmine

“…Chronic liver damage leads to pathological accumulation of ECM proteins (liver fibrosis). Comprehensive characterization of the human ECM molecular composition…”
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COVID-19 disease-Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study by Lanini, Simone, Montaldo, Chiara, Nicastri, Emanuele, Vairo, Francesco, Agrati, Chiara, Petrosillo, Nicola, Scognamiglio, Paola, Antinori, Andrea, Puro, Vincenzo, Di Caro, Antonino, De Carli, Gabriella, Navarra, Assunta, Agresta, Alessandro, Cimaglia, Claudia, Palmieri, Fabrizio, D'Offizi, Gianpiero, Marchioni, Luisa, Kobinger, Gary Pignac, Maeurer, Markus, Girardi, Enrico, Capobianchi, Maria Rosaria, Zumla, Alimuddin, Locatelli, Franco, Ippolito, Giuseppe

“…Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and…”
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Timely HAART initiation may pave the way for a better viral control by Paci, Paola, Martini, Federico, Bernaschi, Massimo, D'Offizi, Gianpiero, Castiglione, Filippo

“…When to initiate antiretroviral therapy in HIV infected patients is a difficult clinical decision. Actually, it is still a matter of discussion whether early…”
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Clinical and virological properties of hepatitis C virus genotype 4 infection in patients treated with different direct-acting antiviral agents by Minosse, Claudia, Selleri, Marina, Giombini, Emanuela, Bartolini, Barbara, Capobianchi, Maria Rosaria, Cerilli, Stefano, Loiacono, Laura, Taibi, Chiara, D'Offizi, Gianpiero, McPhee, Fiona, Garbuglia, AnnaRosa

“…The efficacy of direct-acting antivirals (DAAs) depends on the hepatitis C virus (HCV) genotype 4 (GT4) subtype which are used in the treatment of HCV. We…”
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Activation of Vγ9Vδ2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication by Agrati, Chiara, Alonzi, Tonino, De Santis, Rafaella, Castilletti, Concetta, Abbate, Isabella, Capobianchi, Maria Rosaria, D'Offizi, Gianpiero, Siepi, Francesca, Fimia, Gian Maria, Tripodi, Marco, Poccia, Fabrizio

“…Hepatitis C virus (HCV) has evolved complex strategies to evade host immune responses and establish chronic infection. Since human Vγ9Vδ2 T lymphocytes play a…”
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Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome by Sacchi, Alessandra, Grassi, Germana, Bordoni, Veronica, Lorenzini, Patrizia, Cimini, Eleonora, Casetti, Rita, Tartaglia, Eleonora, Marchioni, Luisa, Petrosillo, Nicola, Palmieri, Fabrizio, D’Offizi, Gianpiero, Notari, Stefania, Tempestilli, Massimo, Capobianchi, Maria Rosaria, Nicastri, Emanuele, Maeurer, Markus, Zumla, Alimuddin, Locatelli, Franco, Antinori, Andrea, Ippolito, Giuseppe, Agrati, Chiara

“…The immunological mechanisms underlying the clinical presentation of SARS-CoV-2 infection and those influencing the disease outcome remain to be defined…”
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Liver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C by Baiocchini, Andrea, Del Nonno, Franca, Taibi, Chiara, Visco-Comandini, Ubaldo, D’Offizi, Gianpiero, Piacentini, Mauro, Falasca, Laura

“…The sinusoidal endothelial cells present in the liver (LSECs) are tipically characterized by the presence of pores (fenestrae). During some pathological…”
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