Search Results - "D'Ercole, A. Joseph"
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Expanding the Mind: Insulin-Like Growth Factor I and Brain Development
Published in Endocrinology (Philadelphia) (01-12-2008)“…Signaling through the type 1 IGF receptor (IGF1R) after interaction with IGF-I is crucial to the normal brain development. Manipulations of the mouse genome…”
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Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells
Published in Glia (01-01-2009)“…Both in vivo and in vitro studies indicate a correlation between reduced acetylation of histone core proteins and oligodendrocyte development. The nature of…”
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Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination
Published in Glia (01-03-2007)“…Insulin‐like growth factor‐I (IGF‐I) has been shown to be a potent agent in promoting the growth and differentiation of oligodendrocyte precursors, and in…”
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Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus
Published in Journal of neuroscience research (01-10-2009)“…Type 1 insulin‐like growth factor receptor (IGF1R) signaling in neuronal development was studied in mutant mice with blunted igf1r gene expression in…”
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β-catenin mediates insulin-like growth factor-I actions to promote cyclin D1 mRNA expression, cell proliferation and survival in oligodendroglial cultures
Published in Glia (01-07-2010)“…By promoting cell proliferation, survival and maturation insulin‐like growth factor (IGF)‐I is essential to the normal growth and development of the central…”
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Lou Underwood: In memoriam
Published in Growth hormone & IGF research (01-04-2015)Get full text
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Insulin-like growth factor actions during development of neural stem cells and progenitors in the central nervous system
Published in Journal of neuroscience research (01-01-2006)“…Insulin‐like growth factor‐I (IGF‐I) plays a key role in normal development. Recent studies show that IGF‐I exerts a wide variety actions in the central…”
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Blunting type 1 insulin-like growth factor receptor expression exacerbates neuronal apoptosis following hypoxic/ischemic injury
Published in BMC neuroscience (30-06-2011)“…Abundant experimental data have implicated an important role for insulin-like growth factor (IGF) in protecting neuronal cells from injury, including…”
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Insulin-Like Growth Factor-I Accelerates the Cell Cycle by Decreasing G1 Phase Length and Increases Cell Cycle Reentry in the Embryonic Cerebral Cortex
Published in The Journal of neuroscience (10-11-2004)“…Neurogenesis in the developing cerebral cortex of mice occurs in the dorsal telencephalon between embryonic day 11 (E11) and E17, during which time the…”
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Myelination Is Altered in Insulin-Like Growth Factor-I Null Mutant Mice
Published in The Journal of neuroscience (15-07-2002)“…Increasing evidence indicates that insulin-like growth factor-I (IGF-I) has an important role in oligodendrocyte development. In this study, we examined…”
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In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system
Published in The European journal of neuroscience (01-04-2004)“…The in vivo actions of insulin‐like growth factor‐I (IGF‐I) on prenatal and early postnatal brain development were investigated in transgenic (Tg) mice that…”
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The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells
Published in Neuron (Cambridge, Mass.) (10-03-2011)“…Cortical development depends on the active integration of cell-autonomous and extrinsic cues, but the coordination of these processes is poorly understood…”
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Insulin‐like growth factor‐I (IGF‐I) inhibits neuronal apoptosis in the developing cerebral cortex in vivo
Published in International journal of developmental neuroscience (01-06-2007)“…Increased expression of insulin‐like growth factor‐I (IGF‐I) in embryonic neural progenitors in vivo has been shown to accelerate neuron proliferation in the…”
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Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice
Published in PloS one (27-06-2013)“…Traumatic brain injury (TBI) survivors often suffer from long-lasting cognitive impairment that stems from hippocampal injury. Systemic administration of…”
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IGF-I Receptor Inhibition Combined with Rapamycin or Temsirolimus Inhibits Neuroblastoma Cell Growth
Published in Anticancer research (01-05-2008)“…Background: Neuroblastoma is the third most common solid tumor in children. Treatment continues to be challenging. The pathogenesis of neuroblastoma has been…”
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Developmental expression of histone deacetylase 11 in the murine brain
Published in Journal of neuroscience research (15-02-2008)“…Recent studies indicate that neural cell development in the central nervous system (CNS) correlates with a reduction in acetylation of histone core proteins…”
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Reduction of spontaneous and irradiation-induced apoptosis in small intestine of IGF-I transgenic mice
Published in American journal of physiology: Gastrointestinal and liver physiology (01-08-2002)“…Insulin-like growth factor I (IGF-I) may promote survival of putative stem cells in the small intestinal epithelium. Mitosis and apoptosis were quantified in…”
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Physiological Differences in Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) Phosphorylation in IGFBP-1 Transgenic Mice
Published in Diabetes (New York, N.Y.) (01-01-2001)“…Physiological Differences in Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) Phosphorylation in IGFBP-1 Transgenic Mice Keiji Sakai , A. Joseph D'Ercole…”
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In memoriam: Louis E. Underwood, MD (1937- 2014)
Published in Pediatric endocrinology reviews : PER (01-12-2014)Get more information
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Increased expression of insulin-like growth factor I augments the progressive phase of synaptogenesis without preventing synapse elimination in the hypoglossal nucleus
Published in Journal of comparative neurology (1911) (22-09-2003)“…The in vivo actions of insulin‐like growth factor I (IGF‐I) on synaptogenesis in the hypoglossal nucleus were investigated in transgenic mice that overexpress…”
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