Search Results - "D'Cruz, Shereen Cynthia"
-
1
Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring
Published in Environment international (01-11-2020)“…•This review identified and prioritized existing effect biomarkers for bisphenols.•119 epidemiologic studies were selected, analyzed, tabulated and…”
Get full text
Journal Article -
2
Transgenerational Inheritance of Environmentally Induced Epigenetic Alterations during Mammalian Development
Published in Cells (Basel, Switzerland) (03-12-2019)“…Genetic studies traditionally focus on DNA as the molecule that passes information on from parents to their offspring. Changes in the DNA code alter heritable…”
Get full text
Journal Article -
3
The effect of environmental contaminants on testicular function
Published in Asian journal of andrology (01-07-2011)“…Male reproductive health has deteriorated considerably in the last few decades. Nutritional, socioeconomic, lifestyle and environmental factors (among others)…”
Get full text
Journal Article -
4
Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: An in vivo and in silico study
Published in Food and chemical toxicology (01-03-2012)“…► BPA administration at low doses induces oxidative stress in rat testis. ► BPA decreases the levels of insulin signaling molecules in rat testis. ► BPA…”
Get full text
Journal Article -
5
Genome-wide analysis of sex-specific differences in the mother–child PELAGIE cohort exposed to organophosphate metabolites
Published in Scientific reports (17-05-2023)“…In recent decades, the detrimental effects of environmental contaminants on human health have become a serious public concern. Organophosphate (OP) pesticides…”
Get full text
Journal Article -
6
Developmental exposure to chlordecone induces transgenerational effects in somatic prostate tissue which are associated with epigenetic histone trimethylation changes
Published in Environment international (01-07-2021)“…•Chlordecone exposure is associated with increased prostate cancer risk.•Chlordecone increases prostatic epithelial neoplasia in F1 and F3 mice.•In exposed…”
Get full text
Journal Article -
7
Gestational exposure to chlordecone promotes transgenerational changes in the murine reproductive system of males
Published in Scientific reports (06-07-2018)“…Environmental factors can affect epigenetic events during germline reprogramming and impose distinctive transgenerational consequences onto the offspring. In…”
Get full text
Journal Article -
8
Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytes
Published in Epigenetics & chromatin (12-08-2021)“…Panobinostat (PB), a histone deacetylase (HDAC) inhibitor drug, is clinically used in the treatment of cancers. We investigated the effects of PB on murine…”
Get full text
Journal Article -
9
Ovarian dysfunction following prenatal exposure to an insecticide, chlordecone, associates with altered epigenetic features
Published in Epigenetics & chromatin (13-05-2019)“…Chlordecone (CD) is an insecticide that was used in the French West Indies for several years to control the banana root borer pest. Given its nonsignificant…”
Get full text
Journal Article -
10
Epigenetic Effects Promoted by Neonicotinoid Thiacloprid Exposure
Published in Frontiers in cell and developmental biology (06-07-2021)“…Background Neonicotinoids, a widely used class of insecticide, have attracted much attention because of their widespread use that has resulted in the decline…”
Get full text
Journal Article -
11
Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence
Published in Environmental research (01-11-2022)“…Pyrethroid metabolites are widely detectable in urine from the general population, including pregnant women and children. Pyrethroids are neurotoxic and…”
Get full text
Journal Article -
12
Kisspeptin as potential biomarker of environmental chemical mixture effect on reproductive hormone profile: A pilot study in adolescent males
Published in The Science of the total environment (10-04-2023)“…Kisspeptin has been proposed as an effect biomarker to understand the mechanisms by which some environmental chemicals adversely affect the human reproductive…”
Get full text
Journal Article -
13
BDNF as a potential mediator between childhood BPA exposure and behavioral function in adolescent boys from the INMA-Granada cohort
Published in The Science of the total environment (10-01-2022)“…Bisphenol A (BPA) exposure has been linked to altered behavior in children. Within the European Human Biomonitoring Initiative (HBM4EU), an adverse outcome…”
Get full text
Journal Article -
14
Bisphenols and Oxidative Stress Biomarkers-Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers
Published in International journal of environmental research and public health (21-05-2020)“…Bisphenols, particularly bisphenol A (4,4'-(hexafluoroisopropylidene)-diphenol) (BPA), are suspected of inducing oxidative stress in humans, which may be…”
Get full text
Journal Article -
15
Exploring the relationship between metal exposure, BDNF, and behavior in adolescent males
Published in International journal of hygiene and environmental health (01-01-2022)“…Brain-derived neurotrophic factor (BDNF) plays an important role in brain development by regulating multiple pathways within the central nervous system. In the…”
Get full text
Journal Article -
16
Effects of plants and plant products on the testis
Published in Asian journal of andrology (01-07-2010)“…For centuries, plants and plant-based products have been used as a valuable and safe natural source of medicines for treating various ailments. The therapeutic…”
Get full text
Journal Article -
17
In utero exposure to chlordecone affects histone modifications and activates LINE-1 in cord blood
Published in Life science alliance (01-06-2021)“…Environmental factors can induce detrimental consequences into adulthood life. In this study, we examined the epigenetic effects induced by in utero…”
Get full text
Journal Article -
18
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro data
Published in Clinical epigenetics (26-12-2022)“…To assess the genetic and epigenetic effects promoted by Bisphenol A (BPA) exposure in adolescent males from the Spanish INMA-Granada birth cohort, and in…”
Get full text
Journal Article -
19
Nonylphenol induces apoptosis via mitochondria- and Fas-l-mediated pathways in the liver of adult male rat
Published in Regulatory toxicology and pharmacology (01-04-2012)“…Nonylphenol (NP) is an environmental contaminant known to possess estrogenic properties. Humans are constantly exposed to NP by contaminated water and food…”
Get full text
Journal Article -
20
A use of homology modeling and molecular docking methods: to explore binding mechanisms of nonylphenol and bisphenol A with antioxidant enzymes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2015)“…Bisphenol A (BPA) and nonylphenol (NP) are phenolic compounds used widely by the industries. BPA and NP are endocrine disruptors possessing estrogenic…”
Get more information
Journal Article