Search Results - "D'Auria, C"

The Bitter Truth: How Insects Cope with Toxic Plant Alkaloids by Leite Dias, Sara, D'Auria, John C

“…Plants are unique organisms that have developed ingenious strategies to cope with environmental challenges, such as herbivorous insects. One of these…”
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Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer by Singel, Kelly L., Grzankowski, Kassondra S., Khan, A. N. M. Nazmul H., Grimm, Melissa J., D’Auria, Anthony C., Morrell, Kayla, Eng, Kevin H., Hylander, Bonnie, Mayor, Paul C., Emmons, Tiffany R., Lénárt, Nikolett, Fekete, Rebeka, Környei, Zsuzsanna, Muthukrishnan, Uma, Gilthorpe, Jonathan D., Urban, Constantin F., Itagaki, Kiyoshi, Hauser, Carl J., Leifer, Cynthia, Moysich, Kirsten B., Odunsi, Kunle, Dénes, Ádám, Segal, Brahm H.

“…Background Advanced cancer causes necrosis and releases damage-associated molecular patterns (DAMPs). Mitochondrial DAMPs activate neutrophils, including…”
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Erythroxylum in Focus: An Interdisciplinary Review of an Overlooked Genus by Restrepo, David A, Saenz, Ernesto, Jara-Muñoz, Orlando Adolfo, Calixto-Botía, Iván F, Rodríguez-Suárez, Sioly, Zuleta, Pablo, Chavez, Benjamin G, Sanchez, Juan A, D'Auria, John C

“…The genus contains species used by indigenous people of South America long before the domestication of plants. Two species, and have been utilized for…”
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NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis by Röhm, Marc, Grimm, Melissa J, D'Auria, Anthony C, Almyroudis, Nikolaos G, Segal, Brahm H, Urban, Constantin F

“…NADPH oxidase is a crucial enzyme in antimicrobial host defense and in regulating inflammation. Chronic granulomatous disease (CGD) is an inherited disorder of…”
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Contribution of CoA Ligases to Benzenoid Biosynthesis in Petunia Flowers by Klempien, Antje, Kaminaga, Yasuhisa, Qualley, Anthony, Nagegowda, Dinesh A., Widhalm, Joshua R., Orlova, Irina, Shasany, Ajit Kumar, Taguchi, Goro, Kish, Christine M., Cooper, Bruce R., D'Auria, John C., Rhodes, David, Pichersky, Eran, Dudareva, Natalia

“…Biosynthesis of benzoic acid from Phe requires shortening of the side chain by two carbons, which can occur via the β-oxidative or nonoxidative pathways. The…”
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Unraveling metabolic patterns and molecular mechanisms underlying storability in sugar beet by Gippert, Anna-Lena, Madritsch, Silvia, Woryna, Patrick, Otte, Sandra, Mayrhofer, Martina, Eigner, Herbert, Garibay-Hernández, Adriana, D'Auria, John C, Molin, Eva M, Mock, Hans-Peter

“…Sugar beet is an important crop for sugar production. Sugar beet roots are stored up to several weeks post-harvest waiting for processing in the sugar…”
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Characterization of a BAHD acyltransferase responsible for producing the green leaf volatile (Z)-3-hexen-1-yl acetate in Arabidopsis thaliana by D'Auria, John C, Pichersky, Eran, Schaub, Andrea, Hansel, Armin, Gershenzon, Jonathan

“…Green-leaf volatiles are commonly emitted from mechanically and herbivore-damaged plants. Derived from the lipoxygenase pathway, these compounds may serve as…”
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Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice by Grimm, Melissa J, Vethanayagam, R Robert, Almyroudis, Nikolaos G, Dennis, Carly G, Khan, A Nazmul H, D'Auria, Anthony C, Singel, Kelly L, Davidson, Bruce A, Knight, Paul R, Blackwell, Timothy S, Hohl, Tobias M, Mansour, Michael K, Vyas, Jatin M, Röhm, Marc, Urban, Constantin F, Kelkka, Tiina, Holmdahl, Rikard, Segal, Brahm H

“…Chronic granulomatous disease, an inherited disorder of the NADPH oxidase in which phagocytes are defective in the generation of superoxide anion and…”
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Arabidopsis thaliana Type I Isopentenyl Diphosphate Isomerases Are Targeted to Multiple Subcellular Compartments and Have Overlapping Functions in Isoprenoid Biosynthesis by Phillips, Michael A, D'Auria, John C, Gershenzon, Jonathan, Pichersky, Eran

“…To form the building blocks of isoprenoids, isopentenyl diphosphate (IPP) isomerase activity, which converts IPP to dimethylallyl diphosphate (DMAPP), appears…”
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Characterization of an Acyltransferase Capable of Synthesizing Benzylbenzoate and Other Volatile Esters in Flowers and Damaged Leaves of Clarkia breweri by D'Auria, John C., Chen, Feng, Pichersky, Eran

“…A cDNA encoding a protein with 456 amino acids whose sequence shows considerable similarity to plant acyltransferases was identified among 750 Clarkia breweri…”
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An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense by Chen, Feng, D'Auria, John C., Tholl, Dorothea, Ross, Jeannine R., Gershenzon, Jonathan, Noel, Joseph P., Pichersky, Eran

“…Summary Emission of methylsalicylate (MeSA), and occasionally of methylbenzoate (MeBA), from Arabidopsis thaliana leaves was detected following the application…”
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Biosynthesis and Emission of Terpenoid Volatiles from Arabidopsis Flowers by Chen, Feng, Tholl, Dorothea, D'Auria, John C., Farooq, Afgan, Pichersky, Eran, Gershenzon, Jonathan

“…Arabidopsis is believed to be mostly self-pollinated, although several lines of genetic and morphological evidence indicate that insect-mediated outcrossing…”
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Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization by Bedewitz, Matthew A., Jones, A. Daniel, D’Auria, John C., Barry, Cornelius S.

“…Tropinone is the first intermediate in the biosynthesis of the pharmacologically important tropane alkaloids that possesses the 8-azabicyclo[3.2.1]octane core…”
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Acetyl-CoA:benzylalcohol acetyltransferase--an enzyme involved in floral scent production in Clarkia breweri by Dudareva, N, D'Auria, J.C, Nam, K.H, Raguso, R.A, Pichersky, E

“…Volatile esters impart distinct characteristics to the floral scent of many plants, and are important in attracting insect pollinators. They are also important…”
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Phylogenomic and synteny analysis of BAHD and SCP/SCPL gene families reveal their evolutionary histories in plant specialized metabolism by Naake, Thomas, D'Auria, John C, Fernie, Alisdair R, Scossa, Federico

“…Plant chemical diversity is largely owing to a number of enzymes which catalyse reactions involved in the assembly, and in the subsequent chemical…”
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S-Adenosyl-l-Methionine:Salicylic Acid Carboxyl Methyltransferase, an Enzyme Involved in Floral Scent Production and Plant Defense, Represents a New Class of Plant Methyltransferases by Ross, Jeannine R, Nam, Kyoung Hee, D'Auria, John C, Pichersky, Eran

“…S-Adenosyl-l-methionine:salicylic acid carboxyl methyltransferase (SAMT) was partially purified from petals of the annual California plant Clarkia breweri…”
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BAHD Company: The Ever-Expanding Roles of the BAHD Acyltransferase Gene Family in Plants by Moghe, Gaurav, Kruse, Lars H, Petersen, Maike, Scossa, Federico, Fernie, Alisdair R, Gaquerel, Emmanuel, D'Auria, John C

“…Plants' ability to chemically modify core structures of specialized metabolites is the main reason why the plant kingdom contains such a wide and rich array of…”
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The Nonredundant Roles of Two 4'-Phosphopantetheinyl Transferases in Vital Processes of Mycobacteria by Chalut, Christian, Botella, Laure, de Sousa-D'Auria, Célia, Houssin, Christine, Guilhot, Christophe

“…Mycobacterium tuberculosis contains >20 enzymes that require activation by transfer of the 4'-phosphopantetheine moiety of CoA onto a conserved serine residue,…”
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A Polyketide Synthase Catalyzes the Last Condensation Step of Mycolic Acid Biosynthesis in Mycobacteria and Related Organisms by Portevin, Damien, de Sousa-D'Auria, Célia, Houssin, Christine, Grimaldi, Christine, Chami, Mohamed, Daffé, Mamadou, Guilhot, Christophe

“…Mycolic acids are major and specific constituents of the cell envelope of Corynebacterineae, a suborder of bacterial species including several important human…”
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Acyltransferases in plants: a good time to be BAHD by D’Auria, John C

“…Acylation is a common and biochemically significant modification of plant secondary metabolites. Plant BAHD acyltransferases constitute a large family of acyl…”
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