Search Results - "D'Ambrosio, Danilo"
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Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from Microcystis aeruguinosa PCC 7806
Published in Chemistry : a European journal (02-04-2013)“…By using the Telospot assay, 27 different extracts of cyanobacteria were evaluated for telomerase inhibition. All extracts showed varying, but significant…”
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2
Extremely thin intermetallic layer in dissimilar AA6061-T6 and mild steel friction stir lap welding using a hemispherical tool
Published in Scientific reports (19-01-2024)“…The dissimilar friction stir lap welding of AA6061-T6 and mild steel using the hemispherical tool tilted towards the retreating side is investigated. Critical…”
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3
Plastic behavior-dependent weldability of heat-treatable aluminum alloys in friction stir welding
Published in International journal of advanced manufacturing technology (01-11-2021)“…The quality of friction stir welding joints is intimately related to the correct mixing of the stirred material. The material flow is strongly dependent on the…”
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Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase
Published in Biochimie (01-03-2012)“…Telomerase is responsible for the immortal phenotype of cancer cells and telomerase inhibition may specifically target cancer cell proliferation. Ligands able…”
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5
New highly hydrosoluble and not self-aggregated perylene derivatives with three and four polar side-chains as G-quadruplex telomere targeting agents and telomerase inhibitors
Published in Bioorganic & medicinal chemistry letters (01-05-2007)“…Four new perylene derivatives with three and four basic side chains, readily soluble in water and not self-aggregated, are presented here. All four compounds…”
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Selective G-quadruplex ligands: The significant role of side chain charge density in a series of perylene derivatives
Published in Bioorganic & medicinal chemistry letters (15-07-2009)“…The human telomeric G-quadruplex structure is a promising target for the design of cancer drugs. The selectivity of G-quadruplex ligands with respect to duplex…”
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The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase
Published in Bioorganic & medicinal chemistry (01-03-2008)“…We have synthesized eight polyamine perylene diimides to conjugate the efficiency of perylene derivatives in stabilizing G-quadruplex structures and the…”
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8
Orthogonal cutting to develop a damage law for severe plastic deformation processes: application to friction stir welding
Published in International journal of advanced manufacturing technology (01-03-2024)“…Damage laws built for numerical simulation are developed from mechanical testing, even if not consistently representative of extreme manufacturing conditions…”
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Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting
Published in Mini reviews in medicinal chemistry (01-12-2009)“…The search for telomerase inhibitors has been widely explored in the last few years, since telomerase activity in somatic cells can be considered as a general…”
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Influence of manufacturing parameters on the mechanical properties of projection stereolithography-manufactured specimens
Published in International journal of advanced manufacturing technology (2019)“…This study focuses on the impact of different fabrication parameters (build orientation, layer thickness and post-curing time) on the mechanical properties of…”
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A new damage evolution criterion for the coupled Eulerian-Lagrangian approach: Application to three-dimensional numerical simulation of segmented chip formation mechanisms in orthogonal cutting
Published in Journal of manufacturing processes (01-01-2022)“…A damage evolution law is proposed to consider the frictional behavior within an Eulerian material after full damage as a Lagrangian material, where the mesh…”
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12
On the potential applications of acoustic emission in friction stir welding
Published in Journal of manufacturing processes (01-03-2022)“…In friction stir welding (FSW), only a few studies related to acoustic emission (AE) signals analysis have been conducted. In this work, the potential…”
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13
Influence of the welding parameters on defectiveness, thermal field and grain size in AA7075-T6 friction stir welds
Published in Welding in the world (2020)Get full text
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