Search Results - "D'Amato, Anthony R"

Exploring the effects of electrospun fiber surface nanotopography on neurite outgrowth and branching in neuron cultures by D'Amato, Anthony R, Puhl, Devan L, Ziemba, Alexis M, Johnson, Christopher D L, Doedee, Janneke, Bao, Jonathan, Gilbert, Ryan J

“…Three aligned, electrospun fiber scaffolds with unique surface features were created from poly-L-lactic acid (PLLA). Fibers without surface nanotopography…”
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TGFβ3 is neuroprotective and alleviates the neurotoxic response induced by aligned poly-l-lactic acid fibers on naïve and activated primary astrocytes by Gottipati, Manoj K., D'Amato, Anthony R., Ziemba, Alexis M., Popovich, Phillip G., Gilbert, Ryan J.

“…Following spinal cord injury, astrocytes at the site of injury become reactive and exhibit a neurotoxic (A1) phenotype, which leads to neuronal death. In…”
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Using Solution Electrowriting to Control the Properties of Tubular Fibrous Conduits by D’Amato, Anthony R, Ding, Xiaochu, Wang, Yadong

“…Multiple additive manufacturing techniques have been developed in recent years to produce structures with tunable physical, chemical, and mechanical properties…”
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Three-Dimensional Printing of Poly(glycerol sebacate) Acrylate Scaffolds via Digital Light Processing by Wu, Yen-Lin, D’Amato, Anthony R, Yan, Alice M, Wang, Richard Q, Ding, Xiaochu, Wang, Yadong

“…Digital light processing (DLP)-based three-dimensional (3D) printing offers large improvements in fabrication throughput and spatial resolution when compared…”
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Electrospun Fibers for Drug Delivery after Spinal Cord Injury and the Effects of Drug Incorporation on Fiber Properties by Johnson, Christopher D L, D'Amato, Anthony R, Gilbert, Ryan J

“…There is currently no cure for individuals with spinal cord injury (SCI). While many promising approaches are being tested in clinical trials, the complexity…”
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Removal of retained electrospinning solvent prolongs drug release from electrospun PLLA fibers by D'Amato, Anthony R., Schaub, Nicholas J., Cardenas, Jesus M., Fiumara, Andrew S., Troiano, Paul M., Fischetti, Andrea, Gilbert, Ryan J.

“…A major challenge in developing drug-releasing electrospun nanofibers is obtaining long-term drug release over many weeks with no burst release of drug. Here,…”
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The effect of engineered nanotopography of electrospun microfibers on fiber rigidity and macrophage cytokine production by Schaub, Nicholas J., D'Amato, Anthony R., Mason, Andrew, Corr, David T., Harmon, Erin Y., Lennartz, Michelle R., Gilbert, Ryan J.

“…Currently, it is unknown how the mechanical properties of electrospun fibers, and the presentation of surface nanotopography influence macrophage gene…”
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Aligned Fingolimod-Releasing Electrospun Fibers Increase Dorsal Root Ganglia Neurite Extension and Decrease Schwann Cell Expression of Promyelinating Factors by Puhl, Devan L, Funnell, Jessica L, D'Amato, Anthony R, Bao, Jonathan, Zagorevski, Dmitri V, Pressman, Yelena, Morone, Daniel, Haggerty, Agnes E, Oudega, Martin, Gilbert, Ryan J

“…Researchers are investigating the use of biomaterials with aligned guidance cues, like those provided by aligned electrospun fibers, to facilitate axonal…”
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Challenges of gene delivery to the central nervous system and the growing use of biomaterial vectors by Puhl, Devan L., D’Amato, Anthony R., Gilbert, Ryan J.

“…•There are several challenges of gene delivery to the central nervous system.•Viral gene delivery has several limitations, but engineered viruses can be…”
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Vastly extended drug release from poly(pro-17β-estradiol) materials facilitates in vitro neurotrophism and neuroprotection by D’Amato, Anthony R., Puhl, Devan L., Ellman, Samuel A. T., Balouch, Bailey, Gilbert, Ryan J., Palermo, Edmund F.

“…Central nervous system (CNS) injuries persist for years, and currently there are no therapeutics that can address the complex injury cascade that develops over…”
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Lactonic Sophorolipid Increases Surface Wettability of Poly‑l‑lactic Acid Electrospun Fibers by Ziemba, Alexis M, Lane, Keith P, Balouch, Bailey, D’Amato, Anthony R, Totsingan, Filbert, Gross, Richard A, Gilbert, Ryan J

“…The hydrophobicity of electrospun poly-l-lactic acid (PLLA) fibers hinders their integration with surrounding tissue for a variety of applications. In this…”
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Evaluation of procedures to quantify solvent retention in electrospun fibers and facilitate solvent removal by D’Amato, Anthony R., Schaub, Nicholas J., Cardenas, Jesus M., Franz, Erich, Rende, Deniz, Ziemba, Alexis M., Gilbert, Ryan J.

“…Electrospun fiber scaffolds crafted from polyesters are studied extensively for potential tissue engineering applications. For translation of electrospun…”
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Poly‑l‑lactic acid-co-poly(pentadecalactone) Electrospun Fibers Result in Greater Neurite Outgrowth of Chick Dorsal Root Ganglia in Vitro Compared to Poly‑l‑lactic Acid Fibers by Ziemba, Alexis M, Lane, Keith P, San Segundo, Ignacio M, D’Amato, Anthony R, Mason, Andrew K, Sexton, Ryan J, Casajus, Hubert, Gross, Richard A, Corr, David T, Gilbert, Ryan J

“…Electrospun poly-l-lactic acid (PLLA) fiber scaffolds are used to direct axonal extension in neural engineering models. We aimed to improve the efficacy of…”
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Stabilized Interleukin-4-Loaded Poly(lactic-co-glycolic) Acid Films Shift Proinflammatory Macrophages toward a Regenerative Phenotype in Vitro by Ziemba, Alexis M, D’Amato, Anthony R, MacEwen, Taylor M, Puhl, Devan L, Koppes, Abigail N, Koppes, Ryan A, Lennartz, Michelle R, Gilbert, Ryan J

“…Macrophages are immune cells involved in wound healing and tissue regeneration; however, the sustained presence of proinflammatory macrophages in wound sites…”
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Experimental and credentialing capital: an adaptable framework for facilitating science outreach for underrepresented youth by Drazan, John F., D'Amato, Anthony R., Winkelman, Max A., Littlejohn, Aaron J., Johnson, Christopher, Ledet, Eric H., Eglash, Ron

“…Increasing the numbers of black, latino and native youth in STEM careers is both an important way to reduce poverty in low income communities, and a…”
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Enhancing Drug Delivery from Electrospun Fiber Scaffolds for Neural Tissue Engineering by D'Amato, Anthony R

“…Spinal cord injury (SCI) is a complex obstacle to overcome as it causes multiple cell types in the spinal cord to undergo detrimental phenotypic changes at…”
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