Search Results - "D'Agostino, Luciano"
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Native DNA electronics: is it a matter of nanoscale assembly?
Published in Nanoscale (14-07-2018)“…The genomic DNA is enveloped by nanotubes formed by the nuclear aggregates of polyamines (NAPs) that induce DNA conformational changes and provide protection…”
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Nuclear aggregates of polyamines in a radiation-induced DNA damage model
Published in The international journal of biochemistry & cell biology (01-02-2014)“…•Single polyamines protect DNA against γ-radiation only at high concentrations.•NAPs might be involved indirectly in DNA protection against radiation…”
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DNA and nuclear aggregates of polyamines
Published in Biochimica et biophysica acta (01-10-2012)“…Polyamines (PAs) are linear polycations that are involved in many biological functions. Putrescine, spermidine and spermine are highly represented in the…”
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Increased IGF-I : IGFBP-3 ratio in patients with hepatocellular carcinoma
Published in Clinical endocrinology (Oxford) (01-12-2003)“…Summary background The development of hepatocellular carcinoma in liver cirrhosis is associated with altered synthesis and secretion of several growth…”
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DNA is Wrapped by the Nuclear Aggregates of Polyamines: The Imaging Evidence
Published in Biomacromolecules (11-04-2011)“…In the cell nucleus, putrescine, spermidine, and spermine self-assemble with phosphate ions to generate three forms of compounds, named nuclear aggregates of…”
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DNA-HMGB1 interaction: The nuclear aggregates of polyamine mediation
Published in Biochimica et biophysica acta (01-10-2016)“…Nuclear aggregates of polyamines (NAPs) are supramolecular compounds generated by the self-assembly of protonated nuclear polyamines (spermine, spermidine and…”
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The in vitro nuclear aggregates of polyamines
Published in The FEBS journal (01-04-2009)“…Natural polyamines (putrescine, spermidine, and spermine) self‐assemble in a simulated physiological environment (50 mm sodium phosphate buffer, pH 7.2),…”
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Mass spectrometric analysis of in vitro nuclear aggregates of polyamines
Published in Rapid communications in mass spectrometry (15-03-2014)“…RATIONALE In the nuclei of eukaryotic cells, polyamines and phosphate ions self‐assemble via ionic interactions and hydrogen bonding, generating three families…”
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Mass spectrometric analysis of in vitro nuclear aggregates of polyamines: Mass spectrometry of iv NAPs
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Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation
Published in The FEBS journal (01-08-2005)“…In a previous study we showed that natural polyamines interact in the nuclear environment with phosphate groups to form molecular aggregates [nuclear…”
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11
The invitro nuclear aggregates of polyamines
Published in The FEBS journal (01-04-2009)“…Natural polyamines (putrescine, spermidine, and spermine) self-assemble in a simulated physiological environment (50mm sodium phosphate buffer, pH7.2),…”
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12
Effects of an appropriate oral diet on the nutritional status of patients with HCV-related liver cirrhosis: A prospective study
Published in Clinical nutrition (Edinburgh, Scotland) (01-10-2005)“…In patients with liver cirrhosis, protein-energy malnutrition is a frequent finding and a risk factor influencing survival. The aim was to estimate the effects…”
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Increased left ventricular mass in pre-liver transplantation cirrhotic patients
Published in Journal of cardiovascular medicine (Hagerstown, Md.) (01-02-2008)“…OBJECTIVESevere liver disease is associated with abnormalities in cardiac geometry and function. We aimed to assess the prevalence of these abnormalities and…”
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Nuclear aggregates of polyamines
Published in IUBMB life (01-02-2006)“…Nuclear aggregates of polyamines (NAPs) are cyclic supramolecular compounds made of polyamines and phosphate groups. Three different aggregates, s‐NAP, m‐NAP…”
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15
Polyamines interact with DNA as molecular aggregates
Published in European journal of biochemistry (01-09-2002)“…New compounds, named nuclear aggregates of polyamines, having a molecular mass of 8000, 4800 and < 1000 Da, were found in the nuclear extracts of several…”
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Interaction of putrescine with nuclear oligopeptides in the enterocyte-like Caco-2 cells
Published in Digestion (01-05-1999)“…Intestinal cells are able both to synthesize and take up putrescine, the main compound of the metabolic polyamine pathway. Polyamine binding to nuclear…”
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A life-threatening case of stenosing pill hypopharynx-oesophagitis caused by a tamsulosin capsule
Published in Digestive and liver disease (01-09-2004)“…Pill oesophagitis is a frequent clinical entity that may induce dysphagia and exceptionally oesophageal occlusion. The mechanisms inducing mucosal inflammation…”
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A Case of Sclerosing Cholangitis Managed by a Percutaneous Approach
Published in Journal of clinical gastroenterology (01-03-2000)“…In 1992, a 61-year-old man who complained of recurrent episodes of fever and jaundice was diagnosed as having sclerosing cholangitis. In the three years that…”
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19
Primary Kaposi sarcoma of the bowel in a HIV‐negative patient
Published in Journal of surgical oncology (01-03-2001)“…A case of Kaposi sarcoma with HIV‐negative and sequence of HHV‐8 positive and exclusive rectosigmoid and descending colon involvement without immunodeficiency…”
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Assessment of small intestinal damage in patients treated with pelvic radiotherapy
Published in Oncology reports (01-05-1998)“…Pelvic radiotherapy almost always induces intestinal symptoms. We investigated the radiation-induced damage to the small intestinal mucosa and evaluated its…”
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