Search Results - "Czlonkowski, Andrzej"

Mechanism of action of three newly registered drugs for multiple sclerosis treatment by Kasarełło, Kaja, Cudnoch-Jędrzejewska, Agnieszka, Członkowski, Andrzej, Mirowska-Guzel, Dagmara

“…Multiple sclerosis (MS) is a disease of suspected autoimmune origin leading to neurodegeneration. The disease pathomechanism is considered to be primarily…”
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The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease by Joniec-Maciejak, Ilona, Ciesielska, Agnieszka, Wawer, Adriana, Sznejder-Pachołek, Anna, Schwenkgrub, Joanna, Cudna, Agnieszka, Hadaczek, Piotr, Bankiewicz, Kristof S, Członkowska, Anna, Członkowski, Andrzej

“…The aim of this study was to examine the effect of AAV2-hIL-10 (vector containing cDNA for human interleukin 10) on dopaminergic system activity (measured as…”
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Potential neuroprotective effect of ibuprofen, insights from the mice model of Parkinson's disease by Świątkiewicz, Maciej, Zaremba, Małgorzata, Joniec, Ilona, Członkowski, Andrzej, Kurkowska-Jastrzębska, Iwona

“…Parkinson's disease (PD) is one of the most common neurodegenerative diseases. An inflammatory reaction seems to be involved in the pathological process in PD…”
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Neurochemical and Behavioral Characteristics of Toxic Milk Mice: An Animal Model of Wilson’s Disease by Przybyłkowski, Adam, Gromadzka, Grażyna, Wawer, Adriana, Bulska, Ewa, Jabłonka-Salach, Katarzyna, Grygorowicz, Tomasz, Schnejder-Pachołek, Anna, Członkowski, Andrzej

“…Toxic milk mice have an inherited defect of copper metabolism. Hepatic phenotype of the toxic milk mice is similar to clinical findings in humans suffering…”
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Effect of human interleukin-10 on the expression of nitric oxide synthases in the MPTP-based model of Parkinson's disease by Schwenkgrub, Joanna, Joniec-Maciejak, Ilona, Sznejder-Pachołek, Anna, Wawer, Adriana, Ciesielska, Agnieszka, Bankiewicz, Krzysztof, Członkowska, Anna, Członkowski, Andrzej

“…Parkinson's disease (PD) is the second most common progressive neurodegenerative disorder. The degeneration of the nigro-striatal pathway has been linked with…”
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The effect of doubling the dose of acetylsalicylic acid (ASA) on platelet function parameters in patients with type 2 diabetes and platelet hyperreactivity during treatment with 75 mg of ASA: a subanalysis of the AVOCADO study by Rosiak, Marek, Postuła, Marek, Kapłon-Cieślicka, Agnieszka, Trzepla, Ewa, Filipiak, Krzysztof J, Członkowski, Andrzej, Opolski, Grzegorz

“…Individuals with diabetes are at 2- to 4-fold higher risk of cardiovascular disease than those without diabetes. High platelet reactivity (HPR) plays a pivotal…”
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Dopamine, serotonin and noradrenaline changes in the striatum of C57BL mice following myelin oligodendrocyte glycoprotein (MOG) 35-55 and complete Freund adjuvant (CFA) administration by Bałkowiec-Iskra, Ewa, Kurkowska-Jastrzebska, Iwona, Joniec, Ilona, Ciesielska, Agnieszka, Członkowska, Anna, Członkowski, Andrzej

“…Many data suggest involvement of inflammation in neurodegeneration. However, the exact mechanisms of this cooperation are poorly understood. We have previously…”
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Influence of age and gender on cytokine expression in a murine model of Parkinson's disease by Ciesielska, Agnieszka, Joniec, Ilona, Kurkowska-Jastrzebska, Iwona, Przybyłkowski, Adam, Gromadzka, Grazyna, Członkowska, Anna, Członkowski, Andrzej

“…The neuroinflammatory reaction has been linked with Parkinson's disease. One of the hypotheses to explain the significance of age and gender (male…”
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Tryptase levels in patients after acute coronary syndromes: The potential new marker of an unstable plaque? by Filipiak, Krzysztof J., Tarchalska‐Krynska, Bozena, Opolski, Grzegorz, Rdzanek, Adam, Kochman, Janusz, Kosior, Dariusz A., Czlonkowski, Andrzej

“…Background: Mast cells (MCs) are multifunctional immune cells that produce a number of vasoactive or thromboactive mediators. Elevated numbers of human heart…”
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The Inflammatory Reaction Following 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Intoxication in Mouse by Kurkowska-Jastrzębska, Iwona, Wrońska, Aneta, Kohutnicka, Małgorzata, Członkowski, Andrzej, Członkowska, Anna

“…In degenerative disorders of the CNS an immune system involvement in the pathological process is postulated. The MPTP model of Parkinson's disease seem to be a…”
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BDNF − 270 C>T polymorphisms might be associated with stroke type and BDNF − 196 G>A corresponds to early neurological deficit in hemorrhagic stroke by Mirowska-Guzel, Dagmara, Gromadzka, Grazyna, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Abstract Genetic factors might be involved in stroke prognosis, however the role of brain-derived neurotrophic factor (BDNF) in stroke recovery is unknown. We…”
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Association of IL1A , IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population by Mirowska-Guzel, Dagmara, Gromadzka, Grazyna, Mach, Anna, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Abstract Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845 G > T (rs17561), L1B- 511 C > T…”
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Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease by Kurkowska-Jastrzębska, Iwona, Litwin, Tomasz, Joniec, Ilona, Ciesielska, Agnieszka, Przybyłkowski, Adam, Członkowski, Andrzej, Członkowska, Anna

“…The pathological process of neurodegeneration, which is observed in Alzheimer's (AD) and Parkinson's (PD) diseases and that follows any insult to the central…”
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Phenotyping analysis of peripheral blood leukocytes in patients with multiple sclerosis by Paź, Aleksandra, Fiszer, Urszula, Zaborski, Jacek, Korlak, Janina, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Multiple sclerosis (MS) is a central nervous disease thought to be elicited by an autoimmune process. Many studies in recent years have concentrated on finding…”
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Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse by Przybyłkowski, Adam, Kurkowska-Jastrzębska, Iwona, Joniec, Ilona, Ciesielska, Agnieszka, Członkowska, Anna, Członkowski, Andrzej

“…Cyclooxygenases (COX) are associated with complex alteration in many pathologies of the central nervous system (CNS). Increased expression of COX-2 has been…”
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Association between BDNF-196 G>A and BDNF-270 C>T polymorphisms, BDNF concentration, and rTMS-supported long-term rehabilitation outcome after ischemic stroke by Mirowska-Guzel, Dagmara, Gromadzka, Grazyna, Seniow, Joanna, Lesniak, Marcin, Bilik, Marta, Waldowski, Konrad, Gruchala, Katarzyna, Czlonkowski, Andrzej, Czlonkowska, Anna

“…The efficacy of rehabilitation in ischemic stroke patients likely varies because of brain plasticity. One of the main neurotrophins in the central nervous…”
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Impact of BDNF -196 G>A and BDNF -270 C>T Polymorphisms on Stroke Rehabilitation Outcome: Sex and Age Differences by Mirowska-Guzel, Dagmara, Gromadzka, Grazyna, Mendel, Tadeusz, Janus-Laszuk, Barbara, Dzierka, Justyna, Sarzynska-Dlugosz, Iwona, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Background: Genetic factors, including gene polymorphisms, are promising in determining stroke rehabilitation outcome. Brain-derived neurotrophic factor (BDNF)…”
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Influence of BDNF polymorphisms on Wilson’s disease susceptibility and clinical course by Mirowska-Guzel, Dagmara, Litwin, Tomasz, Gromadzka, Grazyna, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Susceptibility to Wilson’s disease (WD) and its clinical manifestations are thought to be affected by genetic factors, including polymorphisms. The role of…”
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Age- and sex-differences in the nitric oxide synthase expression and dopamine concentration in the murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Joniec, Ilona, Ciesielska, Agnieszka, Kurkowska-Jastrzebska, Iwona, Przybylkowski, Adam, Czlonkowska, Anna, Czlonkowski, Andrzej

“…Abstract Parkinson's disease (PD) is an age- and sex-related neurodegenerative disorder of unknown aetiology. The involvement of nitric oxide synthase (NOS) in…”
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Association of MMP1 , MMP3 , MMP9 , and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population by Mirowska-Guzel, Dagmara, Gromadzka, Grazyna, Czlonkowski, Andrzej, Czlonkowska, Anna

“…Abstract Single nucleotide polymorphisms in human MMP genes, including MMP1 (− 1637 1G > 2G), MMP3 (− 1612 5A > 6A), MMP9 (− 1562 C > T), and MMP12 (− 82 A >…”
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