Search Results - "Cypser, J"
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Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease
Published in Journal of inherited metabolic disease (01-05-2002)“…More than 40 single‐gene mutants in Caenorhabditis elegans have been demonstrated to lead to increased lifespan (a rigorous, operational test for being a…”
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Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-03-2002)“…We demonstrate here that the nematode Caenorhabditis elegans displays broad hormetic abilities. Hormesis is the induction of beneficial effects by exposure to…”
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Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors
Published in Experimental gerontology (01-09-2000)“…More than 40 mutants in Caenorhabditis elegans have been demonstrated to lead to increased life span (a rigorous, operational test for being a gerontogene) of…”
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A second-generation YAC contig map of human chromosome 3
Published in Nature (London) (28-09-1995)“…A map of human chromosome 3 which integrates both physical and genetic data has been developed from the fusion of two large collections of markers and…”
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Heat shock changes the heterogeneity distribution in populations of Caenorhabditis elegans: does it tell us anything about the biological mechanism of stress response?
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-03-2002)“…In this paper we analyze survival data of populations of sterilized nematodes, Caenorhabditis elegans, exposed to heat shocks of different duration at the…”
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Expression of a single-copy hsp-16.2 reporter predicts life span
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-07-2012)“…The level of green fluorescent protein expression from an hsp-16.2-based transcriptional reporter predicts life span and thermotolerance in Caenorhabditis…”
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Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans
Published in Experimental Gerontology (01-11-2001)“…We review the status of the hypothesis that interventions that increase the resistance to stress offer the potential for effective life prolongation and…”
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Book Review Journal Article -
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The U-Shaped Response of Initial Mortality in Caenorhabditis elegans to Mild Heat Shock: Does It Explain Recent Trends in Human Mortality?
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-07-2008)“…U-shaped dose-response relationships (hormesis) have been documented in numerous biological, toxicological, and pharmacological investigations. For example, in…”
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Direct Observation of Stress Response in Caenorhabditis elegans Using a Reporter Transgene
Published in Cell stress & chaperones (01-12-1999)“…Transgenic Caenorhabditis elegans expressing jellyfish Green Fluorescent Protein under the control of the promoter for the inducible small heat shock protein…”
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Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: the model of balance between cell damage and HSP levels
Published in Experimental gerontology (01-12-2001)“…In this article, we discuss mechanisms responsible for the effects of heat treatment on increasing subsequent survival in the nematode worm Caenorhabditis…”
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Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans
Published in Mechanisms of ageing and development (15-09-2001)“…Stress experiments performed on a population of sterilised nematode worms ( Caenorhabditis elegans) show a clear hormesis effect after short exposure and clear…”
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Journal Article Conference Proceeding -
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Hormesis extends the correlation between stress resistance and life span in long-lived mutants of Caenorhabditis elegans
Published in Human & experimental toxicology (01-06-2001)Get more information
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The spe-10 mutant has longer life and increased stress resistance: Model Systems for Studying General Aging Processes
Published in Neurobiology of aging (1999)Get full text
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The spe-10 mutant has longer life and increased stress resistance
Published in Neurobiology of aging (01-09-1999)“…We investigated the life span of spe-10 mutant nematodes. We also tested resistance of spe-10 mutants to ultraviolet (UV) light, heat, and paraquat and…”
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Heating stress patterns in Caenorhabditis elegans longevity and survivorship
Published in Biogerontology (Dordrecht) (2001)“…Survival data from Caenorhabditis elegans strain TJ1060 (spe-9; fer-15) following brief exposure to 35 degrees C have been investigated. Three experiments with…”
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Molecular Genetic Mechanisms of Life Span Manipulation in Caenorhabditis elegans
Published in Annals of the New York Academy of Sciences (01-06-2000)“…: Aging and a limited life span are fundamental biological realities. Recent studies have demonstrated that longevity can be manipulated and have revealed…”
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A second-generation YAC contig map of human chromosome 3: The genome directory
Published in Nature (London) (1995)Get full text
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Computer Search for Economical Operation of a Hydrothermal Electric System [includes discussion]
Published in Transactions of the American Institute of Electrical Engineers. Part 3, Power apparatus and systems (01-01-1954)“…This paper describes the use of a high-speed digital computer for the purpose of searching for economical modes of operation in a mathematical model of a…”
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Computer search for operating a hydro system
Published in Electrical engineering (New York, N.Y.) (01-09-1954)“…IN SOME INDUSTRIES, the allocation of production among plants, so as to achieve maximum over-all economy, requires the consideration of seasonal variations in…”
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