Search Results - "Cypress, Michael W."

Posttranslational modifications of mitochondrial fission and fusion proteins in cardiac physiology and pathophysiology by Adaniya, Stephanie M, O-Uchi, Jin, Cypress, Michael W, Kusakari, Yoichiro, Jhun, Bong Sook

“…Mitochondrial fragmentation frequently occurs in chronic pathological conditions as seen in various human diseases. In fact, abnormal mitochondrial morphology…”
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Blockade of sodium-glucose cotransporter 2 suppresses high glucose-induced angiotensinogen augmentation in renal proximal tubular cells by Satou, Ryousuke, Cypress, Michael W, Woods, T Cooper, Katsurada, Akemi, Dugas, Courtney M, Fonseca, Vivian A, Navar, L Gabriel

“…Renal proximal tubular angiotensinogen (AGT) is increased by hyperglycemia (HG) in diabetes mellitus, which augments intrarenal angiotensin II formation,…”
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Role of mitochondrial Ca2+ homeostasis in cardiac muscles by Cao, Jessica L., Adaniya, Stephanie M., Cypress, Michael W., Suzuki, Yuta, Kusakari, Yoichiro, Jhun, Bong Sook, O-Uchi, Jin

“…Recent discoveries of the molecular identity of mitochondrial Ca2+ influx/efflux mechanisms have placed mitochondrial Ca2+ transport at center stage in views…”
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Adeno‐associated virus‐based approach for genetic modification of cardiac fibroblasts in adult rat hearts by Nieto, Bridget, Cypress, Michael W., Jhun, Bong Sook, O‐Uchi, Jin

“…Cardiac fibroblasts (CFs) are an attractive target for reducing pathological cardiac remodeling, and understanding the underlying mechanisms of these processes…”
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Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology by Jhun, Bong Sook, O-Uchi, Jin, Adaniya, Stephanie M, Cypress, Michael W, Yoon, Yisang

“…Abnormal mitochondrial morphology, especially fragmented mitochondria, and mitochondrial dysfunction are hallmarks of a variety of human diseases including…”
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α7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension by Vang, Alexander, da Silva Gonçalves Bos, Denielli, Fernandez-Nicolas, Ana, Zhang, Peng, Morrison, Alan R, Mancini, Thomas J, Clements, Richard T, Polina, Iuliia, Cypress, Michael W, Jhun, Bong Sook, Hawrot, Edward, Mende, Ulrike, O-Uchi, Jin, Choudhary, Gaurav

“…Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and dysfunction and is associated with poor outcomes in pulmonary hypertension…”
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A Ca 2+ -activated Cl - Channel Anoctamin-1 Regulates Mitochondrial Morphology by Chaput, Isabel, Cypress, Michael W, Landherr, Maria, Polina, Iuliia, Yoon, Yisang, Jhun, Bong Sook, Choudhary, Gaurav, O-Uchi, Jin

“…The Ca -activated Cl channel Anoctamin-1 (Ano1) regulates multiple cell functions including cell proliferation, survival, and migration. We previously reported…”
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Variation in ORF3a Protein of SARS‐CoV‐2 Decreases The Severity of Host Cell Damage by Landherr, Maria, Cypress, Michael W., Chaput, Isabel, Jhun, Bong Sook, O‐Uchi, Jin, Polina, Iuliia

“…Introduction Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) primarily targets the respiratory system. However, direct SARS‐CoV‐2 infection and…”
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Mitochondrial PKD Activates Mitochondrial Fission and Proliferative Signaling in Cardiac Fibroblasts by Zhou, Xiaoxu, Adhikari, Neeta, Cypress, Michael W., Polina, Iuliia, Landherr, Maria, Chaput, Isabel, Suckow, Mark A., Choudhary, Gaurav, O‐Uchi, Jin, Jhun, Bong Sook

“…Introduction Cardiac fibrosis, characterized by wall stiffening, reduced contractility, and impaired overall heart performance, is a self‐reinforcing process…”
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Short MCU variant forms Ca2+-permeable channel outside of mitochondria by Polina, Iuliia A., Mishra, Jyotsna, Cypress, Michael W., Sook Jhun, Bong, O-Uchi, Jin

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A Ca2+‐activated Cl‐ Channel Anoctamin‐1 Regulates Mitochondrial Morphology by Chaput, Isabel, Cypress, Michael W., Landherr, Maria, Polina, Iuliia, Yoon, Yisang, Jhun, Bong Sook, Choudhary, Gaurav, O‐Uchi, Jin

“…Introduction The Ca2+‐activated Cl‐ channel Anoctamin‐1 (Ano1) regulates multiple cell functions including cell proliferation, survival, and migration. We…”
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Expression of SARS-CoV-2-ORF3a protein induces cardiomyocyte damage by Polina, Iuliia A., Guo, Yugene, Cypress, Michael W., Tolkacheva, Elena G., Sook Jhun, Bong, O-Uchi, Jin

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Abstract 251: Mitochondrial Calcium Uniporter Regulates Proliferative Activity of Cardiac Fibroblasts Under Angiotensin II Stimulation by Jhun, Bong S, Suzuki, Yuta, Cypress, Michael W, Zhang, Peng, Mende, Ulrike, O-Uchi, Jin

“…Abstract only Introduction: Cardiac fibrosis persists in patients with heart failure (HF) even during treatment with conventional HF therapies designed to…”
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Targeting Pyk2‐specific inhibitory peptide in the mitochondrial matrix by Tsobze, Dora Azeudong, Polina, Iuliia, Dileepan, Gayathri, Suzuki, Yuta, Cypress, Michael W., Jhun, Bong Sook, O-Uchi, Jin

“…Abstract only…”
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Cover Image by Nieto, Bridget, Cypress, Michael W., Jhun, Bong Sook, O‐Uchi, Jin

“…The cover image is based on the Short Report Adeno‐associated virus‐based approach for genetic modification of cardiac fibroblasts in adult rat hearts by…”
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Cover Image by Nieto, Bridget, Cypress, Michael W., Jhun, Bong Sook, O‐Uchi, Jin

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Anoctamin‐1 Expression at the Mitochondrial Membrane of Pulmonary Artery Endothelial Cells by Cypress, Michael W., Adaniya, Stephanie M., Suzuki, Yuta, Clements, Richard, O‐Uchi, Jin, Jhun, Bong Sook, Choudhary, Gaurav

“…Anoctamin‐1 (Ano1) is a calcium‐activated chloride channel that can regulate cell proliferation and cell cycle in endothelial cells (ECs). According to a…”
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SARS-CoV-2-ORF3a variant Q57H reduces its pro-apoptotic activity in host cells [version 1; peer review: awaiting peer review] by Landherr, Maria, Polina, Iuliia, Cypress, Michael W., Chaput, Isabel, Nieto, Bridget, Jhun, Bong Sook, O-Uchi, Jin

“…Background Mutations in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enhance its pathogenicity by affecting its…”
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Role of Mitochondrial Ca 2+ ‐Activated Cl − Channel anoctamin‐1 and mitochondrial fusion protein OPA1 in pulmonary arterial hypertension by Cypress, Michael W., Vang, Alexander, Fernandez-Nicolas, Ana, Mancini, Thomas, Jhun, Bong Sook, Clements, Richard T., Choudhary, Gaurav, O-Uchi, Jin

“…Abstract only Activation of a Ca 2+ ‐activated chloride channel, anoctamin‐1 (Ano1), is associated with enhanced cell proliferation in multiple cell types,…”
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Phosphorylation of Mitofusin 2 Regulates Endoplasmic Reticulum‐Mitochondrial Calcium Coupling by Sung, Jae Hwi, Ford, Kara A., Moeller, Jacob, Suzuki, Yuta, Cypress, Michael W., Jhun, Bong Sook, O-Uchi, Jin, Zhang, Peng

“…Abstract only…”
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