Search Results - "Cymbalyuk, Gennady"

Cold-Temperature Coding with Bursting and Spiking Based on TRP Channel Dynamics in Drosophila Larva Sensory Neurons by Maksymchuk, Natalia, Sakurai, Akira, Cox, Daniel N, Cymbalyuk, Gennady S

“…Temperature sensation involves thermosensitive TRP (thermoTRP) and non-TRP channels. larval Class III (CIII) neurons serve as the primary cold nociceptors and…”
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Comodulation of h- and Na + /K + Pump Currents Expands the Range of Functional Bursting in a Central Pattern Generator by Navigating between Dysfunctional Regimes by Ellingson, Parker J, Barnett, William H, Kueh, Daniel, Vargas, Alex, Calabrese, Ronald L, Cymbalyuk, Gennady S

“…Central pattern generators (CPGs), specialized oscillatory neuronal networks controlling rhythmic motor behaviors such as breathing and locomotion, must adjust…”
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Microgeometrical dendritic factors predict electrical decoupling between somatic and dendritic compartments in magnocellular neurosecretory neurons by Korogod, Sergiy M, Stern, Javier E, Cymbalyuk, Gennady S

“…It is generally assumed that dendritic release of neuropeptides from magnocellular neurosecretory neurons (MNNs), a critical process involved in homeostatic…”
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Asymmetric and transient properties of reciprocal activity of antagonists during the paw-shake response in the cat by Parker, Jessica R, Klishko, Alexander N, Prilutsky, Boris I, Cymbalyuk, Gennady S

“…Mutually inhibitory populations of neurons, half-center oscillators (HCOs), are commonly involved in the dynamics of the central pattern generators (CPGs)…”
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A codimension-2 bifurcation controlling endogenous bursting activity and pulse-triggered responses of a neuron model by Barnett, William H, Cymbalyuk, Gennady S

“…The dynamics of individual neurons are crucial for producing functional activity in neuronal networks. An open question is how temporal characteristics can be…”
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Multistability of bursting rhythms in a half-center oscillator and the protective effects of synaptic inhibition by Ellingson, Parker J, Shams, Yousif O, Parker, Jessica R, Calabrese, Ronald L, Cymbalyuk, Gennady S

“…For animals to meet environmental challenges, the activity patterns of specialized oscillatory neural circuits, central pattern generators (CPGs), controlling…”
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Na(+)/K(+) pump interacts with the h-current to control bursting activity in central pattern generator neurons of leeches by Kueh, Daniel, Barnett, William H, Cymbalyuk, Gennady S, Calabrese, Ronald L

“…The dynamics of different ionic currents shape the bursting activity of neurons and networks that control motor output. Despite being ubiquitous in all animal…”
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Transient and Steady-State Properties of Drosophila Sensory Neurons Coding Noxious Cold Temperature by Maksymchuk, Natalia, Sakurai, Akira, Cox, Daniel N, Cymbalyuk, Gennady

“…Coding noxious cold signals, such as the magnitude and rate of temperature change, play essential roles in the survival of organisms. We combined…”
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Chloride-dependent mechanisms of multimodal sensory discrimination and nociceptive sensitization in Drosophila by Himmel, Nathaniel J, Sakurai, Akira, Patel, Atit A, Bhattacharjee, Shatabdi, Letcher, Jamin M, Benson, Maggie N, Gray, Thomas R, Cymbalyuk, Gennady S, Cox, Daniel N

“…Individual sensory neurons can be tuned to many stimuli, each driving unique, stimulus-relevant behaviors, and the ability of multimodal nociceptor neurons to…”
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Propensity for Bistability of Bursting and Silence in the Leech Heart Interneuron by Dashevskiy, Tatiana, Cymbalyuk, Gennady

“…The coexistence of neuronal activity regimes has been reported under normal and pathological conditions. Such multistability could enhance the flexibility of…”
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Six types of multistability in a neuronal model based on slow calcium current by Malashchenko, Tatiana, Shilnikov, Andrey, Cymbalyuk, Gennady

“…Multistability of oscillatory and silent regimes is a ubiquitous phenomenon exhibited by excitable systems such as neurons and cardiac cells. Multistability…”
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Emergence of Extreme Paw Accelerations During Cat Paw Shaking: Interactions of Spinal Central Pattern Generator, Hindlimb Mechanics and Muscle Length-Depended Feedback by Prilutsky, Boris I, Parker, Jessica, Cymbalyuk, Gennady S, Klishko, Alexander N

“…Cat paw shaking is a spinal reflex for removing an irritating stimulus from paw by developing extremely high paw accelerations. Previous studies of paw shaking…”
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Transition between tonic spiking and bursting in a neuron model via the blue-sky catastrophe by SHILNIKOV, Andrey, CYMBALYUK, Gennady

“…We study a continuous and reversible transition between periodic tonic spiking and bursting activities in a neuron model. It is described as the blue-sky…”
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Contributions of h- and Na + /K + Pump Currents to the Generation of Episodic and Continuous Rhythmic Activities by Sharples, Simon A, Parker, Jessica, Vargas, Alex, Milla-Cruz, Jonathan J, Lognon, Adam P, Cheng, Ning, Young, Leanne, Shonak, Anchita, Cymbalyuk, Gennady S, Whelan, Patrick J

“…Developing spinal motor networks produce a diverse array of outputs, including episodic and continuous patterns of rhythmic activity. Variation in excitability…”
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Origin of bursting through homoclinic spike adding in a neuron model by Channell, Paul, Cymbalyuk, Gennady, Shilnikov, Andrey

“…The origin of spike adding in bursting activity is studied in a reduced model of the leech heart interneuron. We show that, as the activation kinetics of the…”
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Contribution of the Na+/K+ Pump to Rhythmic Bursting, Explored with Modeling and Dynamic Clamp Analyses by Erazo-Toscano, Ricardo Javier, Ellingson, Parker J, Calabrese, Ronald L, Cymbalyuk, Gennady S

“…The Na /K pump, often thought of as a background function in neuronal activity, contributes an outward current (Ipump) that responds to the internal…”
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High prevalence of multistability of rest states and bursting in a database of a model neuron by Marin, Bóris, Barnett, William H, Doloc-Mihu, Anca, Calabrese, Ronald L, Cymbalyuk, Gennady S

“…Flexibility in neuronal circuits has its roots in the dynamical richness of their neurons. Depending on their membrane properties single neurons can produce a…”
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AnimatLab: A 3D graphics environment for neuromechanical simulations by Cofer, David, Cymbalyuk, Gennady, Reid, James, Zhu, Ying, Heitler, William J., Edwards, Donald H.

“…The nervous systems of animals evolved to exert dynamic control of behavior in response to the needs of the animal and changing signals from the environment…”
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Control of tumbling during the locust jump by Cofer, David, Cymbalyuk, Gennady, Heitler, William J, Edwards, Donald H

“…Locust can jump precisely to a target, yet they can also tumble during the trajectory. We propose two mechanisms that would allow the locust to control…”
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Homeostatic regulation in a single neuron model from the Pre-Bötzinger Complex by Oginsky, Max F, Cymbalyuk, Gennady S

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