Search Results - "Cvitkovic, F"

Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer by GIACCHETTI, S, PERPOINT, B, BERTHEAUT-CVITKOVIC, F, LARREGAIN-FOURNIER, D, LE ROL, A, WALTER, S, ADAM, R, MISSET, J. L, LEVI, F, ZIDANI, R, LE BAIL, N, FAGGIUOLO, R, FOCAN, C, CHOLLET, P, LLORY, J. F, LETOURNEAU, Y, COUDERT, B

“…To study how adding oxaliplatin (l-OHP) to chronomodulated fluorouracil (5-FU)-leucovorin (LV) affected the objective response rate, as first-line treatment of…”
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Clinical value of circulating endothelial cell levels in metastatic colorectal cancer patients treated with first-line chemotherapy and bevacizumab by Malka, D., Boige, V., Jacques, N., Vimond, N., Adenis, A., Boucher, E., Pierga, J.Y., Conroy, T., Chauffert, B., François, E., Guichard, P., Galais, M.P., Cvitkovic, F., Ducreux, M., Farace, F.

“…We investigated whether circulating endothelial cells (CECs) predict clinical outcome of first-line chemotherapy and bevacizumab in metastatic colorectal…”
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Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery by Giacchetti, S., Itzhaki, M., Gruia, G., Adam, R., Zidani, R., Kunstlinger, F., Brienza, S., Alafaci, E., Bertheault-Cvitkovic, F., Jasmin, C., Reynes, M., Bismuth, H., Misset, J. L., Lévi, F

“…Context: Long-term survival of patients with metastatic colorectal cancer has been achieved only in patients who underwent complete resection of metastases…”
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A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma by Ducreux, M., Rougier, P., Pignon, J.-P., Douillard, J.-Y., Seitz, J.-F., Bugat, R., Bosset, J.-F., Merouche, Y., Raoul, J.-L., Ychou, M., Adenis, A., Berthault-Cvitkovic, F., Luboinski, M.

“…Background: Chemotherapy is moderately efficient as a treatment for pancreatic adenocarcinoma, but patient survival and quality of life has improved with this…”
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Drug-induced Cardiotoxicity Studied by Longitudinal B-Type Natriuretic Peptide Assays and Radionuclide Ventriculography by Pichon, M F, Cvitkovic, F, Hacene, K, Delaunay, J, Lokiec, F, Collignon, M A, Pecking, A P

“…Background: To study the longitudinal variations of plasma B-type natriuretic peptide (BNP) with reference to left ventricular ejection fraction (LVEF) during…”
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Biweekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil, and leucovorin in patients with metastatic colorectal cancer by Bertheault-Cvitkovic, F, Jami, A, Ithzaki, M, Brummer, P D, Brienza, S, Adam, R, Kunstlinger, F, Bismuth, H, Misset, J L, Lévi, F

“…This study sought to determine the feasibility and antitumor efficacy of an intensified three-drug chronomodulated regimen with maximum delivery at 4:00 AM for…”
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A randomized phase II trial evaluating safety and efficacy of an experimental chemotherapy regimen (irinotecan + oxaliplatin, IRINOX) and two standard arms (LV5–FU2 + irinotecan or LV5–FU2 + oxaliplatin) in first-line metastatic colorectal cancer: a study of the Digestive Group of the Fédération Nationale des Centres de Lutte Contre le Cancer by Bécouarn, Y., Senesse, P., Thézenas, S., Boucher, E., Adenis, A., Cany, L., Jacob, J.H., Cvitkovic, F., Montoto-Grillot, C., Ychou, M.

“…To assess activity and safety of an experimental combination of irinotecan and oxaliplatin (IRINOX) as first-line treatment in advanced colorectal cancer. In…”
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High-dose radiation therapy and neoadjuvant plus concomitant chemotherapy with 5-fluorouracil and cisplatin in patients with locally advanced squamous-cell anal canal cancer: Final results of a phase II study by Peiffert, D., Giovannini, M., Ducreux, M., Michel, P., François, E., Lemanski, C., Mirabel, X., Cvitkovic, F., Luporsi, E., Conroy, T., Gérard, J.-P.

“…Summary Purpose: to analyse toxicity and response to a new scheme of neoadjuvant chemotherapy (CT) and concomitant radiochemotherapy (RT-CT) for locally…”
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A phase II study of oral uracil ftorafur (UFT ) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer by BENNOUNA, J, PERRIER, H, MALEK, K, TONELLI, D, DOUILLARD, J. Y, PAILLOT, B, PRIOU, F, JACOB, J. H, HEBBAR, M, BORDENAVE, S, SEITZ, J. F, CVITKOVIC, F, DORVAL, E

“…This phase II trial was performed to evaluate the efficacy and tolerability of a new combination of Uracil/Ftorafur (UFT)/leucovorin (LV) and oxaliplatin in…”
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Treatment intensification by induction chemotherapy (ICT) and radiation dose escalation in locally advanced squamous cell anal canal carcinoma (LAAC): Definitive analysis of the intergroup ACCORD 03 trial by Conroy, T., Ducreux, M., Lemanski, C., Francois, E., Giovannini, M., Cvitkovic, F., Mirabel, X., Bouché, O., Montoto-Grillot, C., Peiffert, D.

“…Abstract only 4033 Background: Concomitant radiochemotherapy (CRT) is the standard treatment of LAAC. The addition of an ICT (2 cycles of 5 FU-Cisplatin) and…”
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A phase I clinical and pharmacokinetic study of capecitabine (Xeloda ) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours by DELORD, J. P, PIERGA, J. Y, MERY-MIGNARD, D, CORNEN, X, MOURI, Z, BUGAT, R, DIERAS, V, BERTHEAULT-CVITKOVIC, F, TURPIN, F. L, LOKIEC, F, LOCHON, I, CHATELUT, E, CANAL, P, GUIMBAUD, R

“…Capecitabine is a highly active oral fluoropyrimidine that is an attractive alternative to 5-fluorouracil in colorectal cancer treatment. The current study,…”
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Multicenter non-randomized phase II study of raltitrexed (Tomudex) and oxaliplatin in non-pretreated metastatic colorectal cancer patients by Seitz, J.-F., Bennouna, J., Paillot, B., Gamelin, E., François, E., Conroy, T., Raoul, J.-L., Becouarn, Y., Bertheault-Cvitkovic, F., Ychou, M., Nasca, S., Fandi, A., Barthelemy, P., Douillard, J.-Y.

“…Background: This multicenter, phase II, open-label study evaluated the antitumor efficacy and safety of oxaliplatin and raltitrexed (Tomudex) in non-pretreated…”
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O.9 Capecitabine (XELODA®, X) and oxaliplatine (ELOXATIN®, LOHP) regimen (XELOX) in elderly patients with metastatic colorectal cancer (MCRC): a FNCLCC French Collaborative Group GERICO 02 phase II study by Rousseau, F, Bugat, R, Ducreux, M, Cvitkovic, F, Carola, E, Gisselbrecht, M, Esterni, B, Gouttenoire, F, Viret, F

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Preliminary results of a phase II study of high-dose radiation therapy and neoadjuvant plus concomitant 5-fluorouracil with CDDP chemotherapy for patients with anal canal cancer: A French cooperative study by Peiffert, D., Seitz, J.-F, Rougier, P., François, E., Cvitkovic, F., Mirabel, X., Nasca, S., Ducreux, M., Hannoun-Levi, J. M., Lusinchi, A., Debrigode, E., Conroy, T., Pignon, J. P., Gérard, J. P.

“…Background Chemotherapy (5-fluorouracil-mitomycin C) concomitant with radiotherapy (RT) increases local control and colostomy-free survival in advanced anal…”
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Overcoming resistance to chronomodulated 5-fluorouracil and folinic acid by the addition of chronomodulated oxaliplatin in advanced colorectal cancer patients by Garufi, C, Brienza, S, Pugliese, P, Aschelter, A M, Bensmaine, M A, Bertheault-Cvitkovic, F, Nisticò, C, Giunta, S, Caterino, M, Giannarelli, D, Cosimelli, M, Lévi, F, Terzoli, E

“…The addition of oxaliplatin (L-OHP) to a 5-fluorouracil (5-FU)/leucovorin (FA) regimen was retrospectively evaluated in 35 consecutive advanced colorectal…”
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Circadian rhythm-modulated chemotherapy with high-dose 5-fluorouracil: a pilot study in patients with pancreatic adenocarcinoma by Bertheault-Cvitkovic, F, Lévi, F, Soussan, S, Brienza, S, Adam, R, Itzhaki, M, Misset, J L, Bismuth, H

“…From November 1986 to April 1989, 16 patients with advanced measurable pancreatic carcinoma were involved in a pilot phase I-II study. 5-Fluorouracil was given…”
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Phase I dose-finding study of BN80927 as an intravenous infusion every 21 days in patients with advanced malignant solid tumors by Lesimple, T., Bertheault-Cvitkovic, F., Delavault, P., Prevost, G., Fohanno, V.

“…Abstract only…”
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Pilot study of 6 weeks of chemoradiotherapy with 5 FU and hydroxyurea in malignant gliomas by CVITKOVIC, F. B, HAIE-MEDER, C, PAPADIMITRAKOPOULOU, V, ARMAND, J. P, CIOLOCA, C, MAUGIS, N, CONSTANS, J. P

“…In an attempt to improve the primary treatment of malignant gliomas we used a concomitant 6-week course of chemoradiotherapy with 5 fluorouracil (5 FU) and…”
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A phase I, open-label, single-arm study for QT assessment of eribulin mesylate in patients with advanced solid tumors by Lesimple, Thierry, Edeline, Julien, Carrothers, Timothy J., Cvitkovic, Frédérique, Darpo, Borje, Delord, Jean-Pierre, Léna, Hervé, Penel, Nicolas, Edwards, Geoff J., Law, Kenneth, Wanders, Jantien, Kristensen, Allan, Reyderman, Larisa

“…Summary Background Several cancer therapies can prolong cardiac repolarization. This study assessed the potential of eribulin to affect cardiac repolarization…”
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Gemcitabine-oxaliplatin combination (SEGEMOX) in anthracycline (A) and taxanes (T) pretreated metastatic breast cancer (MBC): Results from the GERCOR-SEGEMOX phase II trial by Gligorov, J., Cals, L., Tournigand, C., Merad, Z., Dutel, J., Selle, F., Zeghib, N., Chibaudel, B., Cvitkovic, F.

“…Abstract only 1108 Objectives: To evaluate efficacy and safety of SEGEMOX regimen for previously A and T pre-treated MBC patients. Methods: Forty-five women…”
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