Search Results - "Cuzick, J"

Statistical controversies in clinical research: long-term follow-up of clinical trials in cancer by Cuzick, J.

“…Long-term follow-up is an important unmet need for the full analysis of new treatments for cancer. Earlier detection of cancer and more effective treatment…”
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Preventing invasive breast cancer using endocrine therapy by Cuzick, J

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Estimates of benefits and harms of prophylactic use of aspirin in the general population by Cuzick, J., Thorat, M.A., Bosetti, C., Brown, P.H., Burn, J., Cook, N.R., Ford, L.G., Jacobs, E.J., Jankowski, J.A., La Vecchia, C., Law, M., Meyskens, F., Rothwell, P.M., Senn, H.J., Umar, A.

“…Accumulating evidence supports an effect of aspirin in reducing overall cancer incidence and mortality in the general population. We reviewed current data and…”
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Aspirin and cancer risk: a quantitative review to 2011 by Bosetti, C., Rosato, V., Gallus, S., Cuzick, J., La Vecchia, C.

“…Aspirin has been associated to a reduced risk of colorectal and possibly of a few other common cancers. To provide an up-to-date quantification of this…”
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26: Progress in breast cancer prevention by Cuzick, J

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Factors affecting uptake and adherence to breast cancer chemoprevention: a systematic review and meta-analysis by Smith, S.G., Sestak, I., Forster, A., Partridge, A., Side, L., Wolf, M.S., Horne, R., Wardle, J., Cuzick, J.

“…Preventive therapy is a risk reduction option for women who have an increased risk of breast cancer. The effectiveness of preventive therapy to reduce breast…”
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effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women by Harvie, M.N, Pegington, M, Mattson, M.P, Frystyk, J, Dillon, B, Evans, G, Cuzick, J, Jebb, S.A, Martin, B, Cutler, R.G, Son, T.G, Maudsley, S, Carlson, O.D, Egan, J.M, Flyvbjerg, A, Howell, A

“…Background: The problems of adherence to energy restriction in humans are well known. Objective: To compare the feasibility and effectiveness of intermittent…”
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Prognostic value of Ki-67 for prostate cancer death in a conservatively managed cohort by Fisher, G, Yang, Z H, Kudahetti, S, Møller, H, Scardino, P, Cuzick, J, Berney, D M

“…Background: Standard clinical parameters cannot accurately differentiate indolent from aggressive prostate cancer. Our previous work showed that…”
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Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials by Peto, R, Davies, C, Godwin, J, Gray, R, Pan, H C, Clarke, M, Cutter, D, Darby, S, McGale, P, Taylor, C, Wang, Y C, Bergh, J, Di Leo, A, Albain, K, Swain, S, Piccart, M, Pritchard, K

“…Summary Background Moderate differences in efficacy between adjuvant chemotherapy regimens for breast cancer are plausible, and could affect treatment choices…”
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Prognostic value of a cell cycle progression signature for prostate cancer death in a conservatively managed needle biopsy cohort by Cuzick, J, Berney, D M, Fisher, G, Mesher, D, Møller, H, Reid, J E, Perry, M, Park, J, Younus, A, Gutin, A, Foster, C S, Scardino, P, Lanchbury, J S, Stone, S

“…Background: The natural history of prostate cancer is highly variable and it is difficult to predict. We showed previously that a cell cycle progression (CCP)…”
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PIK3CA Mutation, Aspirin Use after Diagnosis and Survival of Colorectal Cancer. A Systematic Review and Meta-analysis of Epidemiological Studies by Paleari, L, Puntoni, M, Clavarezza, M, DeCensi, M, Cuzick, J, DeCensi, A

“…Abstract Aims Regular aspirin use has been associated with inhibition of the whole spectrum of colorectal carcinogenesis, including prevention of metastases…”
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Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study by Dillner, Joakim, Rebolj, Matejka, Birembaut, Philippe, Petry, Karl-Ulrich, Szarewski, Anne, Munk, Christian, de Sanjose, Silvia, Naucler, Pontus, Lloveras, Belen, Kjaer, Susanne, Cuzick, Jack, van Ballegooijen, Marjolein, Clavel, Christine, Iftner, Thomas

“…Objective To obtain large scale and generalisable data on the long term predictive value of cytology and human papillomavirus (HPV) testing for development of…”
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Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group by Dowsett, Mitch, Nielsen, Torsten O., A'Hern, Roger, Bartlett, John, Coombes, R. Charles, Cuzick, Jack, Ellis, Matthew, Henry, N. Lynn, Hugh, Judith C., Lively, Tracy, McShane, Lisa, Paik, Soon, Penault-Llorca, Frederique, Prudkin, Ljudmila, Regan, Meredith, Salter, Janine, Sotiriou, Christos, Smith, Ian E., Viale, Giuseppe, Zujewski, Jo Anne, Hayes, Daniel F.

“…Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear…”
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Use of luteinising-hormone-releasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials by Cuzick, J, Ambroisine, L, Davidson, N, Jakesz, R, Kaufmann, M, Regan, M, Sainsbury, R

“…Summary Background Several trials have been done to assess treatment of premenopausal breast cancer with luteinising-hormone-releasing hormone (LHRH) agonists,…”
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Comparing the performance of six human papillomavirus tests in a screening population by Cuzick, J, Cadman, L, Mesher, D, Austin, J, Ashdown-Barr, L, Ho, L, Terry, G, Liddle, S, Wright, C, Lyons, D, Szarewski, A

“…Background: Several new assays have been developed for high-risk HPV testing of cervical samples; we compare six HPV tests in a screening population. Methods:…”
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Predicted impact of vaccination against human papillomavirus 16 18 on cancer incidence and cervical abnormalities in women aged 20-29 in the UK by Cuzick, J, Castañón, A, Sasieni, P

“…Background: Human papillomavirus (HPV) vaccination has been approved in more than 90 countries and is being implemented in many of these. In the UK,…”
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Validation of an RNA cell cycle progression score for predicting death from prostate cancer in a conservatively managed needle biopsy cohort by Cuzick, J, Stone, S, Fisher, G, Yang, Z H, North, B V, Berney, D M, Beltran, L, Greenberg, D, Møller, H, Reid, J E, Gutin, A, Lanchbury, J S, Brawer, M, Scardino, P

“…Background: The natural history of prostate cancer is highly variable and difficult to predict accurately. Better markers are needed to guide management and…”
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P240 Computerized Quantification of Tumor Infiltrating Lymphocyte (TIL) as a prognostic and predictive factor in ductal carcinoma in situ: Results from the UK/ANZ DCIS randomized trial by Li, H., Madabhushi, A., Badve, S., Cuzick, J., Thorat, M.A.

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Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer by Attard, G, Clark, J, Ambroisine, L, Fisher, G, Kovacs, G, Flohr, P, Berney, D, Foster, C S, Fletcher, A, Gerald, W L, Moller, H, Reuter, V, De Bono, J S, Scardino, P, Cuzick, J, Cooper, C S

“…New predictive markers for managing prostate cancer are urgently required because of the highly variable natural history of this disease. At the time of…”
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Overview of the main outcomes in breast-cancer prevention trials by Cuzick, J, Powles, T, Veronesi, U, Forbes, J, Edwards, R, Ashley, S, Boyle, P

“…Early findings on the use of tamoxifen or raloxifene as prophylaxis against breast cancer have been mixed; we update available data and overview the combined…”
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