Search Results - "Cuvelier, Nicole"

Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death by Schott, Christina, Graab, Ulrike, Cuvelier, Nicole, Hahn, Heidi, Fulda, Simone

“…Recent genomic studies revealed a high rate of recurrent mutations in the RAS pathway in primary rhabdomyosarcoma (RMS) samples. In the present study, we…”
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Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms by Bauer, Julia, Cuvelier, Nicole, Ragab, Nada, Simon-Keller, Katja, Nitzki, Frauke, Geyer, Natalie, Botermann, Dominik S., Elmer, Dominik P., Rosenberger, Albert, Rando, Thomas A., Biressi, Stefano, Fagin, James A., Saur, Dieter, Dullin, Christian, Schildhaus, Hans-Ulrich, Schulz-Schaeffer, Walter, Aberger, Fritz, Uhmann, Anja, Hahn, Heidi

“…A prototypic pediatric cancer that frequently shows activation of RAS signaling is embryonal rhabdomyosarcoma (ERMS). ERMS also show aberrant Hedgehog (HH)/GLI…”
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Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines by Ridzewski, Rosalie, Rettberg, Diana, Dittmann, Kai, Cuvelier, Nicole, Fulda, Simone, Hahn, Heidi

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and is divided into two major histological subgroups, i.e., embryonal (ERMS) and…”
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Total Synthesis of Indole-Derived Allocolchicine Analogues Exhibiting Strong Apoptosis-Inducing Activity by Sitnikov, Nikolay, Velder, Janna, Abodo, Liliane, Cuvelier, Nicole, Neudörfl, Jörg, Prokop, Aram, Krause, Günter, Fedorov, Aleksey Y., Schmalz, Hans-Günther

“…A series of novel pyrrolo‐allocolchicine derivatives (containing a 1‐methyl‐1H‐indol‐5‐yl moiety replacing ring C) was synthesized. The tetracyclic ring system…”
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Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy by Nitzki, Frauke, Tolosa, Ezequiel J, Cuvelier, Nicole, Frommhold, Anke, Salinas-Riester, Gabriela, Johnsen, Steven A, Fernandez-Zapico, Martin E, Hahn, Heidi

“…Mice with heterozygous loss of the tumor suppressor Patched1 (Ptch) develop rhabdomyosarcoma (RMS)-like tumors. However, Ptch transcripts are consistently…”
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