Search Results - "Cuttle, L"

Randomized clinical trial of negative pressure wound therapy as an adjunctive treatment for small‐area thermal burns in children by Frear, C. C., Cuttle, L., McPhail, S. M., Chatfield, M. D., Kimble, R. M., Griffin, B. R.

“…Background The efficacy of negative pressure wound therapy (NPWT) in the acute management of burns remains unclear. The purpose of this trial was to compare…”
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A human skin equivalent burn model to study the effect of a nanocrystalline silver dressing on wound healing by Iljas, J.D., Röhl, J., McGovern, J.A., Moromizato, K.H., Parker, T.J., Cuttle, L.

“…•A new in vitro, multi-cellular, human skin equivalent burn model was developed.•The model displays re-growth after burn injury, but burned native explant does…”
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Randomized controlled trial of three burns dressings for partial thickness burns in children by Gee Kee, E.L, Kimble, R.M, Cuttle, L, Khan, A, Stockton, K.A

“…Highlights • Three burns dressings for partial thickness burns in children were compared. • Wound re-epithelialization time was significantly faster in…”
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Inaccurate, inadequate and inconsistent: A content analysis of burn first aid information online by Burgess, J.D, Cameron, C.M, Cuttle, L, Tyack, Z, Kimble, R.M

“…Highlights • Burn first aid information on the Internet is often inaccurate and inconsistent. • Quality and accuracy of information differs based on a…”
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Cost-effectiveness of silver dressings for paediatric partial thickness burns: An economic evaluation from a randomized controlled trial by Gee Kee, E, Stockton, K, Kimble, R.M, Cuttle, L, McPhail, S.M

“…Highlights • Economic evaluation comparing silver dressings for paediatric partial thickness burns. • 96 children in the trial investigating Acticoat™,…”
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Scar outcome of children with partial thickness burns: A 3 and 6 month follow up by Gee Kee, E.L, Kimble, R.M, Cuttle, L, Stockton, K.A

“…Highlights • Days to re-epithelialization was a predictor of scar quality at 3 and 6 months. • Patient and observer-rated POSAS color scores had a low…”
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Phenytoin Metabolism by Human Cytochrome P450: Involvement of P450 3A and 2C Forms in Secondary Metabolism and Drug-Protein Adduct Formation by CUTTLE, L, MUNNS, A. J, HOGG, N. A, SCOTT, J. R, HOOPER, W. D, DICKINSON, R. G, GILLAM, E. M. J

“…The anticonvulsant phenytoin (5,5-diphenylhydantoin) provokes a skin rash in 5 to 10% of patients, which heralds the start of an idiosyncratic reaction that…”
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Bcl-2 genes and growth factors in the pathology of ischaemic acute renal failure by Gobé, G, Zhang, X‐J, Cuttle, L, Pat, B, Willgoss, D, Hancock, J, Barnard, R, Endre, Z

“…For the past decade, an attempt has been made by many research groups to define the roles of the growing number of Bcl‐2 gene family proteins in the apoptotic…”
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34 Direct Comparison of Different Porcine Thermal Injury Models - Is it Apples to Apples? by Gibson, A, Moffett, L, Andrews, C, Christy, R, Cuttle, L, Kowalczewski, C, Natesan, S, Powell, H, Singer, A, Stone, R, Supp, D

“…Abstract Introduction A vast array of animal models are used in burn injury research, however the porcine model is the most homologous to human skin. The…”
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Collagen in the scarless fetal skin wound: Detection with Picrosirius-polarization by Cuttle, Leila, Nataatmadja, Maria, Fraser, John F., Kempf, Margit, Kimble, Roy M., Hayes, Mark T.

“…Our group has developed an ovine model of deep dermal, partial‐thickness burn where the fetus heals scarlessly and the lamb heals with scar. The comparison of…”
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Randomized controlled trial of three burns dressings for partial thickness burns in children by Gee Kee, E L, Kimble, R M, Cuttle, L, Khan, A, Stockton, K A

“…Background: This study compared the effects of three silver dressing combinations on small to medium size acute partial thickness burns in children, focusing…”
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Randomized controlled trial of three burns dressings for partial thickness burns in children : wound care by Kimble, R.M., Stockton, K.A., Gee Kee, E.L., Khan, A., Cuttle, L.

“…Background: This study compared the effects of three silver dressing combinations on small to medium size acute partial thickness burns in children, focusing…”
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Interleukin-1β induces human proximal tubule cell injury, α-smooth muscle actin expression and fibronectin production by VESEY, David A, CHEUNG, Catherine W. Y, CUTTLE, Leila, ENDRE, Zoltan A, GOBE, Glenda, JOHNSON, David W

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Cytotoxicity of topical antimicrobial agents used in burn wounds in Australasia by Fraser, John F., Cuttle, Leila, Kempf, Margit, Kimble, Roy M.

“…Background:  Burn sepsis is a leading cause of mortality and morbidity in patients with major burns. The use of topical antimicrobial agents has helped improve…”
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Vascular remodeling in the internal mammary artery graft and association with in situ endothelin-1 and receptor expression by SUTHERLAND, Allison J, NATAATMADJA, Maria I, WALKER, Philip J, CUTTLE, Leila, GARLICK, R. Bruce, WEST, Malcolm J

“…The vasoconstricting peptide endothelin-1 (ET-1) has been associated with atherosclerotic cardiovascular disease, vascular smooth muscle cell (VSMC) growth…”
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In vivo and in vitro models demonstrate a role for caveolin-1 in the pathogenesis of ischaemic acute renal failure by Mahmoudi, Mitra, Willgoss, Desley, Cuttle, Leila, Yang, Tao, Pat, Betty, Winterford, Clay, Endre, Zoltan, Johnson, David W, Gobé, Glenda C

“…Caveolae and their proteins, the caveolins, transport macromolecules; compartmentalize signalling molecules; and are involved in various repair processes…”
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Deep dermal burn injury results in scarless wound healing in the ovine fetus by Fraser, John F., Cuttle, Leila, Kempf, Margit, Phillips, Gael E., O'Rourke, Peter K., Choo, Kelvin, Hayes, Mark T., Kimble, Roy M.

“…Early to mid‐term fetuses heal cutaneous incisional wounds without scars; however, fetal response to burn injury has not been ascertained. We present a fetal…”
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Peptic ulcer by CUTTLE, L L D

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Escape from apoptosis after prolonged serum deprivation is associated with the regulation of the mitochondrial death pathway by Bcl-x(l) by Zhang, X J, Yan, J, Cuttle, L, Endre, Z, Gobé, G

“…Bcl-x(l) and Bax play important roles in the regulation of apoptosis. This study investigated the involvement of the mitochondrial death pathway and the role…”
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Bcl-X translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress by Cuttle, L, Zhang, X J, Endre, Z H, Winterford, C, Gobé, G C

“…The molecular pathogenesis of different sensitivities of the renal proximal and distal tubular cell populations to ischemic injury, including…”
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