Search Results - "Cuttitta, Christina M."
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Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity
Published in Nature communications (03-05-2019)“…Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse…”
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LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments
Published in Journal of the American Society of Nephrology (01-10-2020)“…Maintenance of the intricate interdigitating morphology of podocytes is crucial for glomerular filtration. One of the key aspects of specialized podocyte…”
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Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes
Published in Acta crystallographica. Section D, Biological crystallography. (01-05-2014)“…Acoustic droplet ejection (ADE) is a powerful technology that supports crystallographic applications such as growing, improving and manipulating protein…”
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Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening
Published in Acta crystallographica. Section D, Biological crystallography. (01-01-2015)“…Acoustic droplet ejection (ADE) is an emerging technology with broad applications in serial crystallography such as growing, improving and manipulating protein…”
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5
Taurine's effects on the neuroendocrine functions of pancreatic β cells
Published in Advances in experimental medicine and biology (2013)“…Taurine plays significant physiological roles, including those involved in neurotransmission. Taurine is a potent γ-aminobutyric acid (GABA) agonist and alters…”
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Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening
Published in Acta crystallographica. Section D, Biological crystallography. (01-06-2014)“…Acoustic droplet ejection (ADE) is an emerging technology with broad applications in serial crystallography such as growing, improving and manipulating protein…”
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Journal Article -
7
Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening
Published in Acta crystallographica. Section D, Biological crystallography. (01-01-2015)“…An acoustic high-throughput screening method is described for harvesting protein crystals and combining the protein crystals with chemicals such as a fragment…”
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8
Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes
Published in Acta crystallographica. Section D, Biological crystallography. (01-05-2014)“…A method is presented for screening fragment libraries using acoustic droplet ejection to co-crystallize proteins and chemicals directly on micromeshes with as…”
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