Search Results - "Cutler, Christopher E."

Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk by Kudelka, Matthew R., Hinrichs, Benjamin H., Darby, Trevor, Moreno, Carlos S., Nishio, Hikaru, Cutler, Christopher E., Wang, Jianmei, Wu, Huixia, Zeng, Junwei, Wang, Yingchun, Ju, Tongzhong, Stowell, Sean R., Nusrat, Asma, Jones, Rheinallt M., Neish, Andrew S., Cummings, Richard D.

“…Inflammatory bowel disease (IBD) results from aberrant immune stimulation against a dysbiotic mucosal but relatively preserved luminal microbiota and…”
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Cosmc is required for T cell persistence in the periphery by Cutler, Christopher E, Jones, Mark B, Cutler, Alicia A, Mener, Amanda, Arthur, Connie M, Stowell, Sean R, Cummings, Richard D

“…Abstract T lymphocytes, a key arm of adaptive immunity, are known to dynamically regulate O-glycosylation during T cell maturation and when responding to…”
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Intact Reducing Glycan Promotes the Specific Immune Response to Lacto-N-neotetraose-BSA Neoglycoconjugates by Prasanphanich, Nina S, Song, Xuezheng, Heimburg-Molinaro, Jamie, Luyai, Anthony E, Lasanajak, Yi, Cutler, Christopher E, Smith, David F, Cummings, Richard D

“…The mammalian immune system responds to eukaryotic glycan antigens during infections, cancer, and autoimmune disorders, but the immunological bases for such…”
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Synthesis and SAR of 2′,3′-bis-O-substituted N6, 5′-bis-ureidoadenosine derivatives: Implications for prodrug delivery and mechanism of action by Shelton, Jadd R., Cutler, Christopher E., Browning, Megan S., Balzarini, Jan, Peterson, Matt A.

“…A series of 2′,3′-bis-O-silylated or -acylated derivatives of lead compound 3a…”
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Synthesis and SAR of 2',3'-bis-O-substituted N(6), 5'-bis-ureidoadenosine derivatives: implications for prodrug delivery and mechanism of action by Shelton, Jadd R, Cutler, Christopher E, Browning, Megan S, Balzarini, Jan, Peterson, Matt A

“…A series of 2',3'-bis-O-silylated or -acylated derivatives of lead compound 3a…”
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Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N6,5′-bis-ureido- and 5′-carbamoyl-N6-ureidoadenosine derivatives by Shelton, Jadd R., Cutler, Christopher E., Oliveira, Marcelio, Balzarini, Jan, Peterson, Matt A.

“…R=Phenyl, p-chlorophenyl, p-iodophenyl, m-iodophenyl, p-nitrophenyl, p-methoxyphenyl, benzyl, propyl, hexyl, cyclohexyl. We have developed efficient methods…”
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Preliminary SAR analysis of novel antiproliferative N(6),5'-bis-ureidoadenosine derivatives by Peterson, Matt A, Oliveira, Marcelio, Christiansen, Michael A, Cutler, Christopher E

“…A preliminary library of novel N(6),5'-bis-ureidoadenosine analogs and related derivatives was prepared and tested for activity against the NCI 60 panel of…”
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Preliminary SAR analysis of novel antiproliferative N6,5'-bis-ureidoadenosine derivatives by PETERSON, Matt A, OLIVEIRA, Marcelio, CHRISTIANSEN, Michael A, CUTLER, Christopher E

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Luminescent investigations of terbium(III) biosorption as a surrogate for heavy metals and radionuclides by Achyuthan, Komandoor E, Arango, Dulce C, Carles, Elizabeth L, Cutler, Christopher E, Meyer, Lauren A, Brozik, Susan M

“…We describe a metal transport system for investigating the interfacial interactions between the anionic surface charge of a gram-negative bacterium…”
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Role of Cosmc and Tn Antigen in T Cell Biology and the O-Glycoproteome by Cutler, Christopher E

“…T lymphocytes are indispensable to the adaptive immune system and proper execution of their role requires appropriate glycosylation. Despite evidence that…”
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Preliminary SAR analysis of novel antiproliferative N 6,5′-bis-ureidoadenosine derivatives by Peterson, Matt A., Oliveira, Marcelio, Christiansen, Michael A., Cutler, Christopher E.

“…Analogs of lead antiproliferative agent 1 were prepared and tested for activities against the NCI 60 panel of human cancers. Variants in all four canonical…”
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Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N6,5'-bis-ureido- and 5'-carbamoyl-N6-ureidoadenosine derivatives: Symposium-in-Print: Chemical Proteomics by SHELTON, Jadd R, CUTLER, Christopher E, OLIVEIRA, Marcelio, BALZARINI, Jan, PETERSON, Matt A

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