Search Results - "Cuthbert, Gary A."
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Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy
Published in Biomolecules (Basel, Switzerland) (15-12-2020)“…Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety of cells to regulate diverse biological responses. The VEGF-A family…”
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Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease
Published in Cells (Basel, Switzerland) (10-11-2020)“…The process of atherosclerosis leads to the formation of plaques in the arterial wall, resulting in a decreased blood supply to tissues and organs and its…”
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“Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation
Published in The Journal of biological chemistry (01-11-2023)“…In multicellular organisms, a variety of lipid-protein particles control the systemic flow of triacylglycerides, cholesterol, and fatty acids between cells in…”
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Purification and Analysis of Circulating Lipid Particles
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Lipid particles found in circulating extracellular fluids such as blood or lymph are essential for cellular homeostasis, metabolism and survival. Such…”
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Should dialysis-dependent patients with upper limb arterio-venous fistulae undergoing coronary artery bypass grafting avoid having ipsilateral in situ mammary artery grafts?
Published in Interactive cardiovascular and thoracic surgery (01-05-2014)“…A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether dialysis-dependent patients with…”
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Abstract 440: Targeting LOX-1 Scavenger Receptor and oxLDL Uptake With Affimers
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2018)“…Abstract only Introduction: Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1, SREC-1, OLR1) is a class E scavenger receptor which binds oxidized…”
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