Search Results - "Cutaneous and ocular toxicology"

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance by Bhardwaj, Maitry, Chiu, Mei Nee, Pilkhwal Sah, Sangeeta

“…The therapeutic use of humanised monoclonal programmed cell death 1 (PD-1) (pembrolizumab, and nivolumab) and programmed cell death ligand-1 (PD-L1)…”
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Determination of heavy metals (lead, cadmium, arsenic, and mercury) in authorized and unauthorized cosmetics by Saadatzadeh, Afrooz, Afzalan, Sina, Zadehdabagh, Reza, Tishezan, Leila, Najafi, Nahid, Seyedtabib, Maryam, Noori, Seyyed Mohammad Ali

“…Aim: The present study evaluates lead, cadmium, arsenic, and mercury contamination in lipsticks, mascara, eye shadow, and eyebrow pencils, and compares the…”
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A review of methanol poisoning: a crisis beyond ocular toxicology by Pressman, Peter, Clemens, Roger, Sahu, Saura, Hayes, A. Wallace

“…At first blush, methanol poisoning may be seen as an arcane problem generally associated with rapid ocular neuropathy. The emerging clinical reality is that…”
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Human-relevant approaches to assess eye corrosion/irritation potential of agrochemical formulations by Clippinger, Amy J., Raabe, Hans A., Allen, David G., Choksi, Neepa Y., van der Zalm, Anna J., Kleinstreuer, Nicole C., Barroso, João, Lowit, Anna B.

“…There are multiple in vitro and ex vivo eye irritation and corrosion test methods that are available as internationally harmonized test guidelines for…”
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Evaluation of microRNA responses in ARPE-19 cells against the oxidative stress by Ayaz, Lokman, Dinç, Erdem

“…This study aimed to determine microRNA (miRNA) expression profile of human retinal pigment epithelium cell (ARPE-19) against the oxidative stress induced by…”
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Unlocking the role of herbal cosmeceutical in anti-ageing and skin ageing associated diseases by Kumar, Prashant, Verma, Anurag, Ashique, Sumel, Bhowmick, Mithun, Mohanto, Sourav, Singh, Anita, Gupta, Madhu, Gupta, Abhishek, Haider, Tanweer

“…The process of skin ageing is a natural biological phenomenon characterised by the emergence of wrinkles, age spots, sagging skin, and dryness over time. The…”
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Effects on corneal endothelium of intravitreal injection of anti-VEGF drugs by Malvasi, Mariaelena, Calandri, Antonella, Pacella, Elena, Vingolo, Enzo Maria

“…Intravitreal drug administration has become the gold standard for the treatment of many retinal diseases, including age-related macular degeneration (AMD),…”
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Ophthalmic adverse effects of miltefosine in the treatment of leishmaniasis: a systematic review by Pal, Biplab, Atem, Tambe Daniel, Kumari, Sweta, Murti, Krishna, Kumar, Rishikesh, Pandey, Krishna, Siddiqui, Niyamat Ali, Dhingra, Sameer, Chaudhary, Vaibhav

“…Miltefosine stands as the sole oral medication approved for the treatment of leishmaniasis. The appearance of severe ophthalmic toxicities induced by…”
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The effect of intravitreal anti-VEGF injections on choroidal vascular index in patients with diabetic macular edema by Toprak, Aydin, Koc, Hakan, Alpay, Atilla, Ugurbas, Suat Hayri

“…This study aims to examine and compare the effects of intravitreal bevacizumab injection (IVB) at subfoveal 1500 micron (μm) and submacular 6000 μm in patients…”
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The treatment efficacy of 7.5% dapsone gel in papulopustular rosacea: a prospective study by Özkoca, Defne, Caf, Nazlı

“…Topical dapsone has a level A recommendation for the treatment of papulopustular rosacea; however, its treatment efficacy has not been studied previously. The…”
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Isotretinoin increases non-insulin-based surrogate markers of insulin resistance in acne vulgaris patients by Kaya, Kadir, Gevher, Özlem

“…Lipid indices, particularly the triglyceride-glucose index (TyG index) and the triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio, are simple,…”
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Anti-inflammatory, cytotoxic and morphological impact of phycocyanin on ultraviolet radiation irradiated human fibroblast cells by Nowruzi, Bahareh, Sabzevari Joopari, Omid

“…Recently, the use of natural products as skin photoprotective agents has been in increasing demand. This study investigated the bioactivity of phycocyanin (PC)…”
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Impact of oral isotretinoin on the inflammatory markers: can lymphocyte/HDL-C and platelet/HDL-C ratios be new indicators of inflammation in acne vulgaris patients? by Zorlu, Özge, Albayrak, Hülya, Aytekin, Sema

“…The effect of isotretinoin on inflammatory markers has been reported with conflicting results. No studies have been reported on the relationship between…”
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The effects of electronic cigarette smoking on retinal nerve fiber layer, ganglion cell layer, inner plexiform layer, and choroidal thickness by Balasubaramaniam, Dharshini, Lim, Yi Wen, Retnasabapathy, Shamala, A. Qamarruddin, Fazilawati, Singh, Sujaya

“…To compare the thickness of the retinal nerve fibre layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid in healthy electronic…”
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Evaluation of the common skin diseases in patients with malignancies and the cutaneous side effects of cancer treatments by Tamer, Funda, Gharehdaghi, Sheyda, Adisen, Esra

“…The diversity of skin diseases in patients with malignancies leads to diagnostic difficulties and complicate cancer treatment. Furthermore, the increasing use…”
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Enhanced sun protection factor of octocrylene with green tea and bhringraj extracts by M, Pasupathi, B, Natarajan, T, Kumar

“…The aim of this study of sun protection factor boosting effect sunscreen compositions with herbal extract and combination with octocrylene. The standardized…”
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Ocular toxicities of FDA-approved antibody drug conjugates by Vetsa, Shaurey, Zhang, Stephanie, Kay, Walker, Kelkar, Neil, Ghosh, Arko, Alam, Suhail, Hoopes, Phillip C, Moshirfar, Majid

“…Antibody-drug conjugates (ADCs) are an emerging field of cancer treatments that are becoming more widespread in their use. However, there are potential ocular…”
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Choroidal structural changes in inactive thyroid eye disease: a cross-sectional analysis of the choroidal vascularity index by Ermiş, Serhat, Özal, Ece, Savur, Fatma, Karapapak, Murat

“…In this study, we aimed to compare choroidal vascular changes using the Choroidal Vascularity Index (CVI) between patients with inactive Thyroid Eye Disease…”
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Evaluating the concentration dependent dual effects of β-Glucan on cancerous skin cells and mitochondria isolated from melanoma-induced animal model by Arast, Yalda, Esfandiari, Hanife, Kamranfar, Farzane, Mousavi, Zahra, Ameri Shah Reza, Mahdieh, Pourahmad, Jalal

“…Melanoma is still one of the deadliest cancers whose prevalence has increased in recent decades. Today, many polysaccharides and their bioactive compounds have…”
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Evaluation of the early effects of the first-dose administration of the Sinovac vaccine on the retina, choroid, and optic disc using optical coherence tomography (OCT) and OCT-angiography by Yildiz Tasci, Yelda, Icoz, Mehmet, Gurturk Icoz, Sule Gokcek, Saritas, Ozge, Arikan Yorgun, Mucella, Toklu, Yasin

“…To determine the effects of the first-dose administration of the Sinovac vaccine on the retina, choroid, and optic disc in healthy participants. This…”
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