Search Results - "Cusumano, Zachary T"

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  1. 1

    Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist by Spaulding, Caitlin N., Klein, Roger D., Ruer, Ségolène, Kau, Andrew L., Schreiber, Henry L., Cusumano, Zachary T., Dodson, Karen W., Pinkner, Jerome S., Fremont, Daved H., Janetka, James W., Remaut, Han, Gordon, Jeffrey I., Hultgren, Scott J.

    Published in Nature (London) (22-06-2017)
    “…Both F17-like and type 1 pili promote intestinal colonization in mouse colonic crypts, and the high-affinity mannoside M4284 reduces intestinal colonization of…”
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    Journal Article
  2. 2

    Citrulline Protects Streptococcus pyogenes from Acid Stress Using the Arginine Deiminase Pathway and the F₁Fₒ-ATPase by Cusumano, Zachary T, Caparon, Michael G

    Published in Journal of bacteriology (01-04-2015)
    “…A common stress encountered by both pathogenic and environmental bacteria is exposure to a low-pH environment, which can inhibit cell growth and lead to cell…”
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    Journal Article
  3. 3

    Streptococcus pyogenes Arginine and Citrulline Catabolism Promotes Infection and Modulates Innate Immunity by Cusumano, Zachary T, Watson, Jr, Michael E, Caparon, Michael G

    Published in Infection and Immunity (01-01-2014)
    “…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  4. 4
  5. 5

    Development of an immunohistochemical assay for Siglec-15 by Shafi, Saba, Aung, Thazin Nwe, Robbins, Charles, Zugazagoitia, Jon, Vathiotis, Ioannis, Gavrielatou, Niki, Yaghoobi, Vesal, Fernandez, Aileen, Niu, Shuqiong, Liu, Linda N., Cusumano, Zachary T., Leelatian, Nalin, Cole, Kimberley, Wang, He, Homer, Robert, Herbst, Roy S., Langermann, Sol, Rimm, David L.

    Published in Laboratory investigation (01-07-2022)
    “…Siglec-15, a member of sialic-acid binding immunoglobulin type lectins, is normally expressed by myeloid cells and upregulated in some human cancers and…”
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    Journal Article
  6. 6

    Mannose-derived FimH antagonists: a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease by Mydock-McGrane, Laurel K, Cusumano, Zachary T, Janetka, James W

    Published in Expert opinion on therapeutic patents (01-02-2016)
    “…Type 1 pili are utilized by Gram-negative bacteria to adhere to host tissue and thus are a key virulence factor in urinary tract infections (UTIs) and Crohn's…”
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    Journal Article
  7. 7

    Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation by Shu, Qin, Krezel, Andrzej M., Cusumano, Zachary T., Pinkner, Jerome S., Klein, Roger, Hultgren, Scott J., Frieden, Carl

    “…Curli, consisting primarily of major structural subunit CsgA, are functional amyloids produced on the surface of Escherichia coli, as well as many other…”
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  8. 8

    SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes by Port, Gary C, Cusumano, Zachary T, Tumminello, Paul R, Caparon, Michael G

    Published in mBio (28-03-2017)
    “…SpxA is a unique transcriptional regulator highly conserved among members of the phylum that binds RNA polymerase and can act as an antiactivator. Why some…”
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  9. 9

    Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection by Xu, Wei, Flores-Mireles, Ana L., Cusumano, Zachary T., Takagi, Enzo, Hultgren, Scott J., Caparon, Michael G.

    Published in NPJ biofilms and microbiomes (06-11-2017)
    “…Enterococcus faecalis is a leading causative agent of catheter-associated urinary tract infection (CAUTI), the most common hospital-acquired infection. Its…”
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    Journal Article
  10. 10

    Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections by Cusumano, Zachary T, Klein, Roger D, Hultgren, Scott J

    Published in Microbiology spectrum (01-04-2016)
    “…Bacterial adherence to host tissue is an essential process in pathogenesis, necessary for invasion and colonization and often required for the efficient…”
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    Journal Article
  11. 11

    Citrulline Protects Streptococcus pyogenes from Acid Stress Using the Arginine Deiminase Pathway and the F 1 F o -ATPase by Cusumano, Zachary T., Caparon, Michael G.

    Published in Journal of bacteriology (01-04-2015)
    “…ABSTRACT A common stress encountered by both pathogenic and environmental bacteria is exposure to a low-pH environment, which can inhibit cell growth and lead…”
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    Journal Article
  12. 12

    Citrulline Protects Streptococcus pyogenes from Acid Stress Using the Arginine Deiminase Pathway and the F^sub 1^F^sub o^-ATPase by Cusumano, Zachary T, Caparon, Michael G

    Published in Journal of bacteriology (01-04-2015)
    “…A common stress encountered by both pathogenic and environmental bacteria is exposure to a low-pH environment, which can inhibit cell growth and lead to cell…”
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    Journal Article
  13. 13
  14. 14

    SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in italic toggle="yes">Streptococcus pyogenes /italic by Gary C. Port, Zachary T. Cusumano, Paul R. Tumminello, Michael G. Caparon

    Published in mBio (01-05-2017)
    “…ABSTRACT SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an…”
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    Journal Article