Search Results - "Custodio, Ana"

An inexact restoration direct multisearch filter approach to multiobjective constrained derivative-free optimization by Silva, Everton J., Custódio, Ana Luísa

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Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: Beyond KRAS mutations by Custodio, Ana, Feliu, Jaime

“…Abstract The advent of the epidermal growth factor receptor (EGFR)-targeted monoclonal antibodies (mAbs), cetuximab and panitumumab has expanded the range of…”
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Ecophysiological responses of juvenile seabass (Dicentrarchus labrax) exposed to increased temperature and dietary methylmercury by Maulvault, Ana Luísa, Barbosa, Vera, Alves, Ricardo, Custódio, Ana, Anacleto, Patrícia, Repolho, Tiago, Pousão Ferreira, Pedro, Rosa, Rui, Marques, António, Diniz, Mário

“…The ecotoxicological effects of methylmercury (MeHg) exposure have been intensively described in literature. Yet, it is still unclear how marine biota will…”
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Worst-Case Complexity Bounds of Directional Direct-Search Methods for Multiobjective Optimization by Custódio, Ana Luísa, Diouane, Youssef, Garmanjani, Rohollah, Riccietti, Elisa

“…Direct Multisearch is a well-established class of algorithms, suited for multiobjective derivative-free optimization. In this work, we analyze the worst-case…”
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SEOM clinical guideline for the diagnosis and treatment of gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJA) (2019) by Martín-Richard, M., Carmona-Bayonas, A., Custodio, Ana. B., Gallego, J., Jiménez-Fonseca, P., Reina, J. J., Richart, P., Rivera, F., Alsina, M., Sastre, J.

“…Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, it represents the…”
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Detection of Alterations in the Gut Microbiota and Intestinal Permeability in Patients With Hashimoto Thyroiditis by Cayres, Leonardo César de Freitas, de Salis, Larissa Vedovato Vilela, Rodrigues, Guilherme Siqueira Pardo, Lengert, André van Helvoort, Biondi, Ana Paula Custódio, Sargentini, Larissa Donadel Barreto, Brisotti, João Luiz, Gomes, Eleni, de Oliveira, Gislane Lelis Vilela

“…Hashimoto thyroiditis (HT) is the most common autoimmune disease worldwide, characterized by chronic inflammation and circulating autoantibodies against…”
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Correlation of hypertension and proteinuria with outcome in elderly bevacizumab-treated patients with metastatic colorectal cancer by Feliu, Jaime, Salud, Antonieta, Safont, Maria J, García-Girón, Carlos, Aparicio, Jorge, Losa, Ferran, Bosch, Carlos, Escudero, Pilar, Casado, Enrique, Jorge, Monica, Bohn, Uriel, Pérez-Carrión, Ramon, Carmona, Alberto, Custodio, Ana B, Maurel, Joan

“…Studies suggest a relationship between hypertension and outcome in bevacizumab-treated patients with metastatic colorectal cancer (mCRC). We performed a…”
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Longitudinal study of cognitive dysfunctions induced by adjuvant chemotherapy in colon cancer patients by Cruzado, Juan Antonio, López-Santiago, Sonia, Martínez-Marín, Virginia, José-Moreno, Gema, Custodio, Ana Belén, Feliu, Jaime

“…Background Chemotherapy can induce cognitive impairment in cancer patients. The main goal of this longitudinal study was to determine the incidence,…”
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Neuroendocrine Tumor Heterogeneity Adds Uncertainty to the World Health Organization 2010 Classification: Real‐World Data from the Spanish Tumor Registry (R‐GETNE) by Nuñez‐Valdovinos, Barbara, Carmona‐Bayonas, Alberto, Jimenez‐Fonseca, Paula, Capdevila, Jaume, Castaño‐Pascual, Ángel, Benavent, Marta, Pi Barrio, Jose Javier, Teule, Alex, Alonso, Vicente, Custodio, Ana, Marazuela, Monica, Segura, Ángel, Beguiristain, Adolfo, Llanos, Marta, Martinez del Prado, Maria Purificacion, Diaz‐Perez, Jose Angel, Castellano, Daniel, Sevilla, Isabel, Lopez, Carlos, Alonso, Teresa, Garcia‐Carbonero, Rocio

“…Background Gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are a complex family of tumors of widely variable clinical behavior. The World Health…”
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Efficacy of [177Lu]Lu-DOTATATE in metastatic neuroendocrine neoplasms of different locations: data from the SEPTRALU study by Mitjavila, Mercedes, Jimenez-Fonseca, Paula, Belló, Pilar, Pubul, Virginia, Percovich, Juan Carlos, Garcia-Burillo, Amparo, Hernando, Jorge, Arbizu, Javier, Rodeño, Emilia, Estorch, Montserrat, Llana, Belén, Castellón, Maribel, García-Cañamaque, Lina, Gajate, Pablo, Riesco, Maria Carmen, Miguel, Maria Begoña, Balaguer-Muñoz, David, Custodio, Ana, Cano, Juana María, Repetto, Alexandra, Garcia-Alonso, Pilar, Muros, Maria Angustias, Vercher-Conejero, Jose Luis, Carmona-Bayonas, Alberto

“…Background Peptide receptor radionuclide therapy (PRRT) is one of the most promising therapeutic strategies in neuroendocrine neoplasms (NENs). Nevertheless,…”
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Interfacial activation of lipases on hydrophobic support and application in the synthesis of a lubricant ester by Bassi, Jaquelinne J., Todero, Larissa M., Lage, Flávia A.P., Khedy, Gabrielly I., Ducas, Jamile Dell, Custódio, Ana Paula, Pinto, Marilene A., Mendes, Adriano A.

“…•Lipases were successfully immobilized via interfacial activation on poly-methacrylate.•TLL–PMA was the most active biocatalyst in hydrolysis and…”
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SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of gastric cancer (2023) by Rivera, Fernando, Longo, Federico, Martín Richard, Marta, Richart, Paula, Alsina, Maria, Carmona, Alberto, Custodio, Ana Belén, Fernández Montes, Ana, Gallego, Javier, Fleitas Kanonnikoff, Tania

“…Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, the incidence is…”
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Nivolumab plus platinum-doublet chemotherapy in treatment-naive patients with advanced grade 3 Neuroendocrine Neoplasms of gastroenteropancreatic or unknown origin: The multicenter phase 2 NICE-NEC trial (GETNE-T1913) by Riesco-Martinez, Maria Carmen, Capdevila, Jaume, Alonso, Vicente, Jimenez-Fonseca, Paula, Teule, Alex, Grande, Enrique, Sevilla, Isabel, Benavent, Marta, Alonso-Gordoa, Teresa, Custodio, Ana, Anton-Pascual, Beatriz, Hernando, Jorge, Polo, Eduardo, Castillo-Trujillo, Oscar Alfredo, Lamas-Paz, Arantza, Teijo, Ana, Rodriguez-Gil, Yolanda, Soldevilla, Beatriz, Garcia-Carbonero, Rocio

“…The prognosis of patients with advanced high-grade (G3) digestive neuroendocrine neoplasms (NENs) is rather poor. The addition of immune checkpoint inhibition…”
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Bioaccumulation and elimination of mercury in juvenile seabass (Dicentrarchus labrax) in a warmer environment by Maulvault, Ana Luísa, Custódio, Ana, Anacleto, Patrícia, Repolho, Tiago, Pousão, Pedro, Nunes, Maria Leonor, Diniz, Mário, Rosa, Rui, Marques, António

“…Warming is an expected impact of climate change that will affect coastal areas in the future. These areas are also subjected to strong anthropogenic pressures…”
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SEOM-GEMCAD-TTD Clinical Guideline for the diagnosis and treatment of esophageal cancer (2021) by Fernández-Montes, Ana, Alcaide, Julia, Alsina, María, Custodio, Ana Belén, Franco, Lourdes Fernández, Gallego Plazas, Javier, Gómez-Martín, Carlos, Richart, Paula, Rivera, Fernando, Martin-Richard, Marta

“…Esophageal cancer is an aggressive tumor, and is the sixth-leading cause of death from cancer. Incidence is rising in Spain, particularly among men. Two main…”
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Predicting Chemotherapy Toxicity in Older Patients with Cancer: A Multicenter Prospective Study by Feliu, Jaime, Jiménez‐Munárriz, Beatriz, Basterretxea, Laura, Paredero, Irene, Llabrés, Elisenda, Antonio‐Rebollo, Maite, Losada, Beatriz, Espinosa, Enrique, Gironés, Regina, Custodio, Ana Belén, del Mar Muñoz, María, Díaz‐Almirón, Mariana, Gómez‐Mediavilla, Jeniffer, Pinto, Alvaro, Torregrosa, María‐Dolores, Soler, Gema, Cruz, Patricia, Higuera, Oliver, Molina‐Garrido, María José

“…Background Standard oncology tools are inadequate to distinguish which older patients are at higher risk of developing chemotherapy‐related complications…”
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The PALBONET Trial: A Phase II Study of Palbociclib in Metastatic Grade 1 and 2 Pancreatic Neuroendocrine Tumors (GETNE‐1407) by Grande, Enrique, Teulé, Alex, Alonso‐Gordoa, Teresa, Jiménez‐Fonseca, Paula, Benavent, Marta, Capdevila, Jaume, Custodio, Ana, Vera, Ruth, Munarriz, Javier, La Casta, Adelaida, Díez, Juan José, Gajate, Pablo, Molina‐Cerrillo, Javier, Matos, Ignacio, Cristóbal, Eva María, Ruffinelli, José C., Palacios, José, García‐Carbonero, Rocío

“…Lessons Learned Palbociclib demonstrated no detectable activity in molecularly unselected and heavily pretreated patients with advanced grade 1/2 pancreatic…”
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Cytokines and Pancreatic Ductal Adenocarcinoma: Exploring Their Relationship with Molecular Subtypes and Prognosis by Gutierrez-Sainz, Laura, Heredia-Soto, Victoria, Rodríguez-García, Ana Margarita, Crespo Sánchez, María Gema, Serrano-Olmedo, María Gemma, Molero-Luis, Marta, Losantos-García, Itsaso, Ghanem, Ismael, Pérez-Wert, Pablo, Custodio, Ana, Mendiola, Marta, Feliu, Jaime

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by its poor prognosis. The current challenge remains the absence of predictive biomarkers. Cytokines…”
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Second-line treatment in advanced gastric cancer: Data from the Spanish AGAMENON registry by Cotes Sanchís, Almudena, Gallego, Javier, Hernandez, Raquel, Arrazubi, Virginia, Custodio, Ana, Cano, Juana María, Aguado, Gema, Macias, Ismael, Lopez, Carlos, López, Flora, Visa, Laura, Garrido, Marcelo, Martínez Lago, Nieves, Fernández Montes, Ana, Limón, María Luisa, Azkárate, Aitor, Pimentel, Paola, Reguera, Pablo, Ramchandani, Avinash, Cacho, Juan Diego, Martín Carnicero, Alfonso, Granja, Mónica, Martín Richard, Marta, Hernández Pérez, Carolina, Hurtado, Alicia, Serra, Olbia, Buxo, Elvira, Vidal Tocino, Rosario, Jimenez-Fonseca, Paula, Carmona-Bayonas, Alberto, Buyukhatipoglu, Hakan

“…Background Second-line treatments boost overall survival in advanced gastric cancer (AGC). However, there is a paucity of information as to patterns of use and…”
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3'UTR Polymorphism in ACSL1 Gene Correlates with Expression Levels and Poor Clinical Outcome in Colon Cancer Patients by Vargas, Teodoro, Moreno-Rubio, Juan, Herranz, Jesús, Cejas, Paloma, Molina, Susana, Mendiola, Marta, Burgos, Emilio, Custodio, Ana B, De Miguel, María, Martín-Hernández, Roberto, Reglero, Guillermo, Feliu, Jaime, Ramírez de Molina, Ana

“…Strong evidence suggests that lipid metabolism (LM) has an essential role in tumor growth to support special energetic and structural requirements of tumor…”
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