Search Results - "Custódio, Beatriz"
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PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia
Published in Journal of controlled release (10-12-2018)“…Drug delivery to the central nervous system is restricted by the blood-brain barrier (BBB). However, with the onset of stroke, the BBB becomes leaky, providing…”
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One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimicrobial Peptides Using “Photoclick” Chemistry: Validation Using the Gastric Bacterium Helicobacter pylori
Published in ACS applied materials & interfaces (27-03-2024)“…Surface bioconjugation of antimicrobial peptides (AMP) onto nanoparticles (AMP-NP) is a complex, multistep, and time-consuming task. Herein, a microfluidic…”
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Breaking Barriers: Bioinspired Strategies for Targeted Neuronal Delivery to the Central Nervous System
Published in Pharmaceutics (23-02-2020)“…Central nervous system (CNS) disorders encompass a vast spectrum of pathological conditions and represent a growing concern worldwide. Despite the high social…”
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Antioxidant, antimutagenic, and hypoglycemic properties of flours by different parts of marolo (Annona crassiflora Mart.) seeds: Film and almond
Published in Food research international (01-11-2024)“…[Display omitted] •α-glucosidase inhibition, antioxidant and chemopreventive potential were assessed in marolo seeds.•Myricetin and p-coumaric acid were the…”
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Anonna crassiflora suppresses colonic carcinogenesis through its antioxidant effects, bioactive amines, and phenol content in rats
Published in Food research international (01-01-2024)“…Marolo (Annona crassiflora) is an underutilized Brazilian Cerrado fruit with few reports in the literature about its bioactive compounds and functional…”
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Extraction of bioactive amines from grated Parmesan cheese using acid, alkaline and organic solvents
Published in Journal of food composition and analysis (01-05-2007)“…Ion-pair-HPLC, post-column derivatization with o-phthalaldehyde and fluorimetric detection is the method of choice for the separation and quantification of…”
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Bioactive amines in fresh beef liver and influence of refrigerated storage and pan-roasting
Published in Food control (01-02-2016)“…The profile and levels of ten bioactive amines in fresh beef liver was determined and associated with physico-chemical parameters of quality. Furthermore, the…”
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Assessment of the quality of refrigerated and frozen pork by multivariate exploratory techniques
Published in Meat science (01-05-2018)“…Pork loin and leg were evaluated 24h after slaughter and during refrigerated (5°C) and frozen storage for microbial counts, pH, total volatile base nitrogen…”
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Biological Response Following the Systemic Injection of PEG-PAMAM-Rhodamine Conjugates in Zebrafish
Published in Pharmaceutics (01-05-2024)“…Numerous therapeutic and diagnostic approaches used within a clinical setting depend on the administration of compounds via systemic delivery. Biomaterials at…”
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Total mercury in commercial fishes and estimation of Brazilian dietary exposure to methylmercury
Published in Journal of trace elements in medicine and biology (01-12-2020)“…•Total mercury occurrence was investigated in 18 different fish species.•Farmed fish showed low levels of total mercury.•Estimated methylmercury intake was…”
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Adjuvantes e Via de Administração no Desenvolvimento de Vacinas
Published 01-01-2021“…Esta monografia pretende sintetizar os principais conceitos para o desenvolvimento de novos adjuvantes, novas associações de adjuvantes e novas aplicações para…”
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Dissertation -
13
A eficácia organizacional no âmbito dos centros públicos de procriação medicamente assistida: da entropia à inovação
Published 01-01-2021“…A evolução sociodemográfica portuguesa caracteriza-se pela diminuição da natalidade, diminuição do número de filhos por mulher e pelo aumento da idade média da…”
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Dissertation -
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QSAR and molecular modelling studies on B-DNA recognition of minor groove binders
Published in European journal of medicinal chemistry (01-02-2003)“…Aromatic bisamidines have been proved to be efficient compounds against Leishmania spp. and Pneumocystis carinii. Although the mode of action is still not…”
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Dietary exposure to high-intensity sweeteners by the Brazilian self-declared diabetic population and general Brazilian population
Published in Food and chemical toxicology (01-12-2024)“…Due to an increasing use of high-intensity sweeteners in foods and potential health implications of high levels exposure, the intake of high-intensity…”
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Controlo Através de Meios de Vigilância à Distância: O GPS
Published 01-01-2017“…A presente dissertação tem como objetivo a análise dos meios de vigilância à distância. Este tema surgiu na medida em que o desenvolvimento das novas…”
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Dissertation -
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AS DIFERENTES TERMINOLOGIAS DA TIRA CÔMICA NO LIVRO DIDÁTICO
Published in Revista X (Curitiba, Brazil) (25-06-2020)“…As tiras cômicas ficaram conhecidas pelo formato tendencialmente curto, horizontal e retangular de seus quadrinhos, resultado de uma padronização adotada pelos…”
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Delivery of Nucleic Acids in Brain Ischemia Mediated by Dendrimers: The Challenge of Crossing the Blood-Brain Barrier
Published 01-01-2018“…Ischemic stroke is a pathology with high economical and social impact in today’s western-world society with the lack of effective therapies and the persistence…”
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