Search Results - "Custer, MC"

Efficient Transfer of a Tumor Antigen-Reactive TCR to Human Peripheral Blood Lymphocytes Confers Anti-Tumor Reactivity by Clay, Timothy M, Custer, Mary C, Sachs, Jessica, Hwu, Patrick, Rosenberg, Steven A, Nishimura, Michael I

“…The tumor-associated-Ag MART-1 is expressed by most human melanomas. The genes encoding an alphabeta TCR from a MART-1-specific, HLA-A2-restricted, human T…”
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Characterization of an antibody that can detect the Kai1/CD82 murine metastasis suppressor by Custer, Mary C., Risinger, John I., Hoover, Shelley, Simpson, R. Mark, Patterson, Tricia, Barrett, J. Carl

“…BACKGROUND Kai1, also known as CD82, is a member of the tetraspanin family (TM4SF). The human homolog, KAI1, is an activation antigen of T‐cells and is a…”
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Changes in the Fine Specificity of gp100(209-217)-Reactive T Cells in Patients Following Vaccination with a Peptide Modified at an HLA-A2.1 Anchor Residue by Clay, Timothy M, Custer, Mary C, McKee, Mark D, Parkhurst, Maria, Robbins, Paul F, Kerstann, Keith, Wunderlich, John, Rosenberg, Steven A, Nishimura, Michael I

“…In a recent clinical trial, HLA-A2+ melanoma patients were vaccinated with a peptide derived from the melanoma Ag gp100, which had been modified at the second…”
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MHC class I-restricted recognition of a melanoma antigen by a human CD4+ tumor infiltrating lymphocyte by NISHIMURA, M. I, AVICHEZER, D, CUSTER, M. C, LEE, C. S, CHEN, C, PARKHURST, M. R, DIAMOND, R. A, ROBBINS, P. F, SCHWARTZENTRUBER, D. J, ROSENBERG, S. A

“…It is generally considered that MHC class I-restricted antigens are recognized by CD8+ T cells, whereas MHC class II-restricted antigens are recognized by CD4+…”
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Cellular mechanisms of the antitumor activity of recombinant IL-6 in mice by Mule, JJ, Custer, MC, Travis, WD, Rosenberg, SA

“…The systemic administration of human rIL-6 to mice resulted in the regression of established, 3-day pulmonary micrometastases from two weakly immunogenic…”
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In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2 by Lotze, MT, Matory, YL, Ettinghausen, SE, Rayner, AA, Sharrow, SO, Seipp, CA, Custer, MC, Rosenberg, SA

“…Purified recombinant human interleukin 2 (RIL 2) derived from E. coli containing the inserted gene encoding for IL 2 was administered to 20 patients with a…”
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IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes by Kawakami, Y, Custer, MC, Rosenberg, SA, Lotze, MT

“…IL-4 is a pluripotent lymphokine acting on various cell types. We investigated the role of human IL-4 on the generation of lymphokine-activated killer (LAK)…”
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IL-7 induces human lymphokine-activated killer cell activity and is regulated by IL-4 by Stotter, H, Custer, MC, Bolton, ES, Guedez, L, Lotze, MT

“…Induction of lymphokine-activated killer (LAK) activity by IL-2 has been described and characterized as broadly cytolytic activity against both fresh and…”
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T cell-receptor V gene use by CD4+ melanoma-reactive clonal and oligoclonal T-cell lines by Nishimura, M I, Custer, M C, Schwarz, S L, Parker, L L, Mixon, A, Clay, T M, Yannelli, J R, Rosenberg, S A

“…Tumor-reactive CD4+ T cells can be isolated and expanded from the peripheral blood and tumor lesions of patients with melanoma. In contrast to CD8+ T cells,…”
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Retroviral transduction of interferon-γ cDNA into a nonimmunogenic murinefibrosarcoma : generation of T cells in draining lymph nodes capable of treating established parental metastatic tumor by SHILONI, E, KARP, S. E, CUSTER, M. C, SHILYANSKY, J, RESTIFO, N. P, ROSENBERG, S. A, MULE, J. J

“…Gene modification of tumor cells with the cDNA for interferon γ (IFNγ) has been shown to increase the immunogenicity of some tumor cells. In order to explore…”
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Identification of a T-cell receptor from a therapeutic murine T-cell clone by Shilyansky, J, Yang, J C, Custer, M C, Spiess, P, Mixon, A, Cole, D J, Mulé, J J, Rosenberg, S A, Nishimura, M I

“…Tumor-infiltrating lymphocytes (TIL) have been successfully used for the treatment of metastatic malignancies in clinical trials and in experimental animal…”
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A biologic assay for IL-4. Rapid fluorescence assay for IL-4 detection in supernatants and serum by Custer, M C, Lotze, M T

“…Interleukin-4 (IL-4) is a lymphokine produced by activated T helper cells with effects on T cells, B cells, monocytes and mast cells. The conventional…”
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Specific binding and lysis of human melanoma by IL-2-activated cells coated with anti-T3 or anti-Fc receptor cross-linked to antimelanoma antibody: a possible approach to the immunotherapy of human tumors by Lotze, M T, Roberts, K, Custer, M C, Segal, D A, Rosenberg, S A

“…Monoclonal antibodies (MoAb) to human melanoma have demonstrated a limited ability to cause tumor regression in humans when used alone or when coupled to…”
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Cells invading tumors: strategies for the identification and expansion of tumor reactive lymphocytes by Lotze, M T, Ross, W G, Tomita, S, Custer, M C

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Lactoferrin and transferrin fragments react with nitrite to form an inhibitor of Bacillus cereus spore outgrowth by Custer, M C, Hansen, J N

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Intraperitoneal administration of interleukin-2 in patients with cancer by Lotze, M T, Custer, M C, Rosenberg, S A

“…We have administered 11 to 64 doses of recombinant interleukin-2 (IL-2) ranging from 10,000 to 300,000 U/kg, given three times daily as a bolus infusion…”
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