Search Results - "Cusimano, Michael D"

Practice guideline: Idiopathic normal pressure hydrocephalus: Response to shunting and predictors of response by Halperin, John J, Kurlan, Roger, Schwalb, Jason M, Cusimano, Michael D, Gronseth, Gary, Gloss, David

“…Objective: We evaluated evidence for utility of shunting in idiopathic normal pressure hydrocephalus (iNPH) and for predictors of shunting effectiveness…”
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Multimorbidity states associated with higher mortality rates in organ dysfunction and sepsis: a data-driven analysis in critical care by Zador, Zsolt, Landry, Alexander, Cusimano, Michael D, Geifman, Nophar

“…Sepsis remains a complex medical problem and a major challenge in healthcare. Diagnostics and outcome predictions are focused on physiological parameters with…”
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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy by Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

“…Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive tumorigenesis. However, the origin of intratumoural functional heterogeneity…”
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DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management by Nassiri, Farshad, Mamatjan, Yasin, Suppiah, Suganth, Badhiwala, Jetan H, Mansouri, Sheila, Karimi, Shirin, Saarela, Olli, Poisson, Laila, Gepfner-Tuma, Irina, Schittenhelm, Jens, Ng, Ho-Keung, Noushmehr, Houtan, Harter, Patrick, Baumgarten, Peter, Weller, Michael, Preusser, Matthias, Herold-Mende, Christel, Tatagiba, Marcos, Tabatabai, Ghazaleh, Sahm, Felix, von Deimling, Andreas, Zadeh, Gelareh, Aldape, Kenneth D

“…Abstract Background Variability in standard-of-care classifications precludes accurate predictions of early tumor recurrence for individual patients with…”
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PRMT5 inhibition disrupts splicing and stemness in glioblastoma by Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.

“…Glioblastoma (GBM) is a deadly cancer in which cancer stem cells (CSCs) sustain tumor growth and contribute to therapeutic resistance. Protein arginine…”
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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells by Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.

“…Glioblastomas exhibit a hierarchical cellular organization, suggesting that they are driven by neoplastic stem cells that retain partial yet abnormal…”
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Head Trauma in Mixed Martial Arts by Hutchison, Michael G., Lawrence, David W., Cusimano, Michael D., Schweizer, Tom A.

“…Background: Mixed martial arts (MMA) is a full combative sport with a recent global increase in popularity despite significant scrutiny from medical…”
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Bodychecking rules and concussion in elite hockey by Donaldson, Laura, Asbridge, Mark, Cusimano, Michael D

“…Athletes participating in contact sports such as ice hockey are exposed to a high risk of suffering a concussion. We determined whether recent rule changes…”
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Predictors of falls and mortality among elderly adults with traumatic brain injury: A nationwide, population-based study by Fu, Wayne W, Fu, Terence S, Jing, Rowan, McFaull, Steven R, Cusimano, Michael D

“…Elderly adults are at particular risk of sustaining a traumatic brain injury (TBI), and tend to suffer worse outcomes compared to other age groups. Falls are…”
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Diffusion Tensor Imaging Findings in Post-Concussion Syndrome Patients after Mild Traumatic Brain Injury: A Systematic Review by Khong, Edrea, Odenwald, Nicole, Hashim, Eyesha, Cusimano, Michael D

“…To review the evidence for the use of diffusion tensor imaging (DTI) parameters in the human brain as a diagnostic tool for and predictor of post-concussion…”
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Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives by Di Ieva, Antonio, Lam, Timothy, Alcaide-Leon, Paula, Bharatha, Aditya, Montanera, Walter, Cusimano, Michael D

“…Susceptibility weighted imaging (SWI) is a relatively new imaging technique. Its high sensitivity to hemorrhagic components and ability to depict…”
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Social determinants of health associated with psychological distress stratified by lifetime traumatic brain injury status and sex: Cross-sectional evidence from a population sample of adults in Ontario, Canada by Chan, Vincy, Marcus, Lauren, Burlie, Danielle, Mann, Robert E, Toccalino, Danielle, Cusimano, Michael D, Ilie, Gabriela, Colantonio, Angela

“…This study identified the social determinants of health (SDoH) associated with psychological distress in adults with and without a self-reported history of…”
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The Fundamental Need for Sleep in Neurocritical Care Units: Time for a Paradigm Shift by Kishore, Kislay, Cusimano, Michael D.

“…Intensive neurological assessments in neurocritical care settings for unduly prolonged period result in profound sleep deprivation in those patients that…”
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Open data and injuries in urban areas-A spatial analytical framework of Toronto using machine learning and spatial regressions by Vaz, Eric, Cusimano, Michael D, Bação, Fernando, Damásio, Bruno, Penfound, Elissa

“…Injuries have become devastating and often under-recognized public health concerns. In Canada, injuries are the leading cause of potential years of life lost…”
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The effectiveness of helmet wear in skiers and snowboarders: a systematic review by Cusimano, Michael D, Kwok, Judith

“…To summarise the best available evidence to determine the impact of helmet use on head injuries, neck injuries and cervical spine injuries in skiers and…”
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Suicidality, bullying and other conduct and mental health correlates of traumatic brain injury in adolescents by Ilie, Gabriela, Mann, Robert E, Boak, Angela, Adlaf, Edward M, Hamilton, Hayley, Asbridge, Mark, Rehm, Jürgen, Cusimano, Michael D

“…Our knowledge on the adverse correlates of traumatic brain injuries (TBI), including non-hospitalized cases, among adolescents is limited to case studies. We…”
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Epidemiological Trends of Traumatic Brain Injury Identified in the Emergency Department in a Publicly-Insured Population, 2002-2010 by Fu, Terence S, Jing, Ruwei, Fu, Wayne W, Cusimano, Michael D

“…To examine epidemiological trends of Traumatic Brain Injury (TBI) treated in the Emergency Department (ED), identify demographic groups at risk of TBI, and…”
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Microvascularization of Grade I meningiomas: effect on tumor volume, blood loss, and patient outcome by Karsy, Michael, Burnett, Brian, Di Ieva, Antonio, Cusimano, Michael D, Jensen, Randy L

“…OBJECTIVE Quantitative assessment of tumor microvascularity has the potential to improve prognostication, advance understanding of tumor biology, and help…”
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Reliability of Task-Based fMRI for Preoperative Planning: A Test-Retest Study in Brain Tumor Patients and Healthy Controls by Morrison, Melanie A, Churchill, Nathan W, Cusimano, Michael D, Schweizer, Tom A, Das, Sunit, Graham, Simon J

“…Functional magnetic resonance imaging (fMRI) continues to develop as a clinical tool for patients with brain cancer, offering data that may directly influence…”
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Understanding the psychiatric effects of concussion on constructed identity in hockey players: Implications for health professionals by Todd, Ryan, Bhalerao, Shree, Vu, Michael T, Soklaridis, Sophie, Cusimano, Michael D

“…The following study was undertaken to investigate the effect of concussion and psychiatric illness on athletes and their caregivers. Semi-structured interviews…”
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