Search Results - "Curzon, P."

Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors by Bannon, A. W., Decker, M. W., Holladay, M. W., Curzon, P., Donnelly-Roberts, D., Puttfarcken, P. S., Bitner, R. S., Diaz, A., Dickenson, A. H., Porsolt, R. D., Williams, M., Arneric, S. P.

“…Development of analgesic agents for the treatment of severe pain requires the identification of compounds that are devoid of opioid receptor liabilities. A…”
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Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat by Bitner, R.S., Nikkel, A.L., Curzon, P., Donnelly-Roberts, D.L., Puttfarcken, P.S., Namovic, M., Jacobs, I.C., Meyer, M.D., Decker, M.W.

“…Pharmacological activation of neuronal nicotinic acetylcholine receptors can produce non-opioid antinociception in rodents. However, multiple nAChR subtypes…”
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Influence of Separate and Combined Septal and Amygdala Lesions on Memory, Acoustic Startle, Anxiety, and Locomotor Activity in Rats by Decker, M.W., Curzon, P., Brioni, J.D.

“…The septohippocampal system and the amygdala have been implicated in cognitive and emotional processes. A series of experiments was conducted to examine the…”
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Cognition enhancing effects of novel H 3 receptor (H 3 R) antagonists in several animal models by Fox, G. B., Pan, J. B., Lewis, A. M., Browman, K. E., Komater, V. A., Buckley, M. J., Curzon, P., Radek, R. J., Faghih, R., Esbenshade, T. A., Cowart, M. D., Decker, M. W., Hancock, A. A.

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Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636 by Lin, C W, Bianchi, B R, Miller, T R, Stashko, M A, Wang, S S, Curzon, P, Bednarz, L, Asin, K E, Britton, D R

“…A-77636 is a dopamine (DA) D1 receptor-selective agonist that was previously shown to elicit beneficial responses in animal models of Parkinson's disease (PD)…”
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Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration by Britton, D R, Curzon, P, Mackenzie, R G, Kebabian, J W, Williams, J E, Kerkman, D

“…Rats trained to self-administer cocaine (0.75 mg/kg/infusion) on an FR-5 schedule were treated with selective D1 or D2 antagonists. A69045, a D1 antagonist…”
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All-Cause Mortality Following an Acute Coronary Syndrome: 12-Year Follow-Up of the Comprehensive 2002 New Zealand Acute Coronary Syndrome Audit by Ellis, Chris J., Gamble, Greg D., Williams, Michael J.A., Matsis, Phil, Elliott, John M., Devlin, Gerry, Mann, Stewart, French, John K., White, Harvey D.

“…To describe the long-term mortality of a complete national cohort of acute coronary syndrome (ACS) patients enrolled in 2002, to compare this with a national…”
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Effects of heart rate reduction with ivabradine on exercise-induced myocardial ischemia and stunning by Monnet, X, Ghaleh, B, Colin, P, de Curzon, O P, Giudicelli, J F, Berdeaux, A

“…We investigated the effects of the selective bradycardic agent ivabradine, an I(f) channel inhibitor, on exercise-induced ischemia and resulting myocardial…”
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Experiences formally verifying a network component by Curzon, P.

“…Errors in network components can have disastrous effects so it is important that all aspects of the design are correct. We describe our experiences formally…”
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Orthodontic headgear related to allergic contact dermatitis by Brooks, M H, Curzon, P G

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Evaluation of a stable CCK agonist (A68552) in conditioned avoidance responding in mice, rats, and primates: comparison with typical and atypical antipsychotics by Britton, D R, Curzon, P, Yahiro, L, Buckley, M, Tufano, M, Nadzan, A

“…In a variety of in vivo and in vitro tests, cholecystokinin (CCK) has been shown to produce effects that would suggest a functional antagonism of dopamine. On…”
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Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia by RUETER, Lynne E, BALLARD, Michael E, GALLAGHER, Kelly B, BASSO, Ana Maria, CURZON, Peter, KOHLHAAS, Kathy L

“…The rat neonatal ventral hippocampal (VH) ibotenic lesion model has been proposed as a developmental model of schizophrenia, based on evidence that it…”
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Structure−Activity Studies and Analgesic Efficacy of N-(3-Pyridinyl)-Bridged Bicyclic Diamines, Exceptionally Potent Agonists at Nicotinic Acetylcholine Receptors by Bunnelle, William H, Daanen, Jerome F, Ryther, Keith B, Schrimpf, Michael R, Dart, Michael J, Gelain, Arianna, Meyer, Michael D, Frost, Jennifer M, Anderson, David J, Buckley, Michael, Curzon, Peter, Cao, Ying-Jun, Puttfarcken, Pamela, Searle, Xenia, Ji, Jianguo, Putman, C. Brent, Surowy, Carol, Toma, Lucio, Barlocco, Daniela

“…A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of…”
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A-412997, a selective dopamine D 4 agonist, improves cognitive performance in rats by Browman, Kaitlin E., Curzon, Peter, Pan, Jia Bao, Molesky, Angela L., Komater, Victoria A., Decker, Michael W., Brioni, Jorge D., Moreland, Robert B., Fox, Gerard B.

“…The recent development of a highly selective dopamine D 4 receptor agonist, A-412997 (2-(3′,4′,5′,6′-tetrahydro-2′ H-[2,4′] bipyridinyl-1′-yl)- N-…”
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Enhancement of prepulse inhibition of startle in mice by the H 3 receptor antagonists thioperamide and ciproxifan by Browman, Kaitlin E, Komater, Victoria A, Curzon, Peter, Rueter, Lynne E, Hancock, Arthur A, Decker, Michael W, Fox, Gerard B

“…Histamine H 3 receptor antagonists/inverse agonists have been proposed as potential therapeutic agents for the treatment of a number of neurological disorders…”
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Hybrid tool integrating HOL theorem proving with MDG model checking by Mizouni, R., Tahar, S., Curzon, P.

“…We describe a hybrid tool for hardware formal verification that links the HOL theorem prover and the MDG (multiway decision graphs) model checker. Our tool…”
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Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan by BROWMAN, Kaitlin E, KOMATER, Victoria A, CURZON, Peter, RUETER, Lynne E, HANCOCK, Arthur A, DECKER, Michael W, FOX, Gerard B

“…Histamine H3 receptor antagonists/inverse agonists have been proposed as potential therapeutic agents for the treatment of a number of neurological disorders…”
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Models of interactive systems: a case study on programmable user modelling by Blandford, Ann, Butterworth, Richard, Curzon, Paul

“…Models of interactive systems can be used to answer focused questions about those systems. Making the appropriate choice of modelling technique depends on what…”
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Mechanism of action of A-85380 in an animal model of depression by Buckley, Michael J., Surowy, Carol, Meyer, Michael, Curzon, Peter

“…A role for neuronal nicotinic receptor (NNR) activation in animal models of depression has been established. In order to determine the mechanism by which NNR…”
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Automating the verification of parameterized hardware using a hybrid tool by Curzon, P., Tahar, S.

“…We outline how a hybrid formal hardware verification tool that links an interactive theorem prover and an automated hardware verification tool, can verify…”
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