Lipid parameters in obese and normal weight patients with or without chronic periodontitis

Lipid parameters in obese and normal weight patients with or without chronic periodontitis

Objective The aim of this study was to evaluate the serum levels of lipids in patients with normal weight (NW) or obesity with or without chronic periodontitis (ChP). Materials and methods One hundred and sixty non-smoking patients without history of diabetes and/or cardiovascular events were alloca...

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Bibliographic Details
Published in:Clinical oral investigations Vol. 22; no. 1; pp. 161 - 167
Main Authors: Cury, Eduardo Zaccarias, Santos, Vanessa Renata, Maciel, Suellen da Silva, Gonçalves, Tiago Eduardo Dias, Zimmermann, Glaucia Santos, Mota, Rosa Maria Salani, Figueiredo, Luciene Cristina, Duarte, Poliana Mendes
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 2018
Springer Nature B.V
Subjects:
Adult
Cholesterol
Chronic Periodontitis - blood
Dentistry
Diabetes mellitus
Dyslipidemia
Dyslipidemias - blood
Female
Gum disease
High density lipoprotein
Humans
Lipids
Lipids - blood
Low density lipoprotein
Male
Medicine
Metabolic disorders
Middle Aged
Obesity
Obesity - blood
Original Article
Periodontitis
Risk Factors
Serum levels
Smoking
Triglycerides
Obesity
Triglycerides
Chronic periodontitis
High-density lipoprotein cholesterol
Total cholesterol
Low-density lipoprotein cholesterol
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Summary:Objective The aim of this study was to evaluate the serum levels of lipids in patients with normal weight (NW) or obesity with or without chronic periodontitis (ChP). Materials and methods One hundred and sixty non-smoking patients without history of diabetes and/or cardiovascular events were allocated into one of the following groups: NW patients with periodontal health (NWH; n  = 40), NW patients with ChP (NWChP; n  = 40), obese patients with periodontal health (ObH; n  = 40), and obese patients with ChP (ObChP; n  = 40). Serum levels of total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TRG) were estimated. Results After adjustments for gender and age, both NW groups presented lower levels of TRG than both obese groups ( p  < 0.05). The NWH group presented lower levels of LDL than both periodontitis groups ( p  < 0.05) and the lowest TC/HDL ratio when compared to the other groups ( p  < 0.05). Females from the NWH group exhibited higher levels of HDL and lower LDL/HDL ratio than females from the ObChP group ( p  < 0.05). Furthermore, individuals from the ObChP group were more likely to have levels of LDL ≥130 mg/dl and HDL ≤40 mg/dl, compared to those from the NWH group ( p  < 0.05). Conclusions ChP and obesity, jointly or individually, are associated with undesirable pro-atherogenic lipid profiles. Clinical relevance There is interest in identifying clinical conditions associated with dyslipidemia to improve preventive and treatment strategies. This study demonstrated that ChP, obesity, and the association of both conditions might be related to pro-atherogenic lipid profiles.
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ISSN:1432-6981
1436-3771
DOI:10.1007/s00784-017-2095-1