Search Results - "Curtis, Wendy"
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Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models
Published in Oncoimmunology (02-01-2018)“…Recent advances in cancer treatment with checkpoint blockade of receptors such as CTLA-4 and PD-1 have demonstrated that combinations of agents with…”
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Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity
Published in BMC neuroscience (24-12-2005)“…Autosomal recessive juvenile parkinsonism (AR-JP) is caused by mutations in the parkin gene which encodes an E3 ubiquitin-protein ligase. Parkin is thought to…”
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Norepinephrine- and Epinephrine-deficient Mice Gain Weight Normally on a High-fat Diet
Published in Obesity (Silver Spring, Md.) (01-09-2005)“…OBJECTIVE: Signaling through adrenergic receptors (ARs) by norepinephrine (NE) and epinephrine (Epi) regulates weight gain when mice are fed a high-fat diet…”
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Anti-B-cell Maturation Antigen Chimeric Antigen Receptor T cell Function against Multiple Myeloma Is Enhanced in the Presence of Lenalidomide
Published in Molecular cancer therapeutics (01-12-2019)“…Anti-B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells have shown promising clinical responses in patients with relapsed/refractory…”
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Abstract 4062: A novel method for generating regulated cytokine therapeutics: Safety and activity of a conditionally active cLAG3-IL2 capable of delivering IL2 to LAG3+ cells while remaining inert on LAG3- cells
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract IL-2 is a powerful cytokine central to the generation of an effective immune response. However, its use in cancer immunotherapy has been limited by…”
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Lenalidomide Enhances Anti-BCMA Chimeric Antigen Receptor T Cell Function Against Multiple Myeloma
Published in Blood (08-12-2017)“…The development of chimeric antigen receptor (CAR) T cells that target antigens expressed on the surface of malignant plasma cells is a promising new treatment…”
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Rats Perform Better on Spatial Than Brightness Delayed Matching-to-Sample Water-Escape Due to an Unlearned Bias to Use Spatial Cues
Published in Physiology & behavior (01-11-1996)“…Rats readily acquire water-escape spatial delayed matching-to-sample (DMTS) tasks and show excellent performance with retention intervals as long as 120 m…”
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Nonclinical evaluation of the combination of mouse IL-21 and anti- mouse CTLA-4 or PD-1 blocking antibodies in mouse tumor models
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 3019 Background: Interleukin 21 (IL-21), a γc chain family cytokine, is produced primarily by CD4+ T cells and has many effects on immune cells,…”
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Neuropeptide Y Protects against Methamphetamine-Induced Neuronal Apoptosis in the Mouse Striatum
Published in The Journal of neuroscience (01-06-2005)“…Methamphetamine (METH) is an illicit drug that causes neuronal apoptosis in the mouse striatum, in a manner similar to the neuronal loss observed in…”
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