Search Results - "Curtis, Sean P."

Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison by Laine, Loren, Prof, Curtis, Sean P, MD, Cryer, Byron, MD, Kaur, Amarjot, PhD, Cannon, Christopher P, MD

“…Summary Background Upper gastrointestinal safety of cyclo-oxygenase (COX)-2 selective inhibitors versus traditional non-steroidal anti-inflammatory drugs…”
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Lower Gastrointestinal Events in a Double-Blind Trial of the Cyclo-Oxygenase-2 Selective Inhibitor Etoricoxib and the Traditional Nonsteroidal Anti-Inflammatory Drug Diclofenac by Laine, Loren, Curtis, Sean P, Langman, Michael, Jensen, Dennis M, Cryer, Byron, Kaur, Amarjot, Cannon, Christopher P

“…Background & Aims Nonsteroidal anti-inflammatory drugs (NSAIDs) cause lower gastrointestinal (GI) clinical events such as bleeding. Cyclo-oxygenase (COX)-2…”
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Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial by Rawal, Narinder, Viscusi, Eugene, Peloso, Paul M, Minkowitz, Harold S, Chen, Liang, Shah, Sandhya, Mehta, Anish, Chitkara, Denesh K, Curtis, Sean P, Papanicolaou, Dimitris A

“…Optimal postoperative pain management is important to ensure patient comfort and early mobilization. In this double-blind, placebo- and active-controlled,…”
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Gastrointestinal side effects of etoricoxib in patients with osteoarthritis: results of the Etoricoxib versus Diclofenac Sodium Gastrointestinal Tolerability and Effectiveness (EDGE) trial by BARAF, Herbert S. B, FUENTEALBA, Carlos, GREENWALD, Maria, BRZEZICKI, Jan, O'BRIEN, Katherine, SOFFER, Beth, POLIS, Adam, BIRD, Steven, KAUR, Amarjot, CURTIS, Sean P

“…OBJECTIVE:. To compare the gastrointestinal (GI) tolerability, safety, and efficacy of etoricoxib and diclofenac in patients with osteoarthritis (OA). METHODS:…”
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Efficacy and safety of golimumab in patients with non-radiographic axial spondyloarthritis: a withdrawal and retreatment study (GO-BACK) by Weinstein, Cindy L J, Sliwinska-Stanczyk, Paula, Hála, Tomas, Stanislav, Marina, Tzontcheva, Anjela, Yao, Ruji, Berd, Yuliya, Curtis, Sean P, Philip, George

“…Abstract Objectives The GO-BACK study was designed to evaluate the efficacy and safety of golimumab (GLM) treatment withdrawal in adults with non-radiographic…”
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Long-term tolerability and efficacy of golimumab in active non-radiographic axial spondyloarthritis: results from open-label extension by van der Heijde, Désirée, Dougados, Maxime, Maksymowych, Walter P, Bergman, Gina, Curtis, Sean P, Tzontcheva, Anjela, Huyck, Susan, Philip, George, Sieper, Joachim

“…Abstract Objectives We report the open-label extension (OLE) of the GO-AHEAD study evaluating the long-term efficacy and safety of golimumab (GLM) in patients…”
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Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis by Holmes, Michael V., Lange, Leslie A., Palmer, Tom, Lanktree, Matthew B., North, Kari E., Almoguera, Berta, Buxbaum, Sarah, Chandrupatla, Hareesh R., Elbers, Clara C., Guo, Yiran, Hoogeveen, Ron C., Li, Jin, Li, Yun R., Swerdlow, Daniel I., Cushman, Mary, Price, Tom S., Curtis, Sean P., Fornage, Myriam, Hakonarson, Hakon, Patel, Sanjay R., Redline, Susan, Siscovick, David S., Tsai, Michael Y., Wilson, James G., van der Schouw, Yvonne T., FitzGerald, Garret A., Hingorani, Aroon D., Casas, Juan P., de Bakker, Paul I.W., Rich, Stephen S., Schadt, Eric E., Asselbergs, Folkert W., Reiner, Alex P., Keating, Brendan J.

“…Elevated body mass index (BMI) associates with cardiometabolic traits on observational analysis, yet the underlying causal relationships remain unclear. We…”
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Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison by Cannon, Christopher P, Curtis, Sean P, FitzGerald, Garret A, Krum, Henry, Kaur, Amarjot, Bolognese, James A, Reicin, Alise S, Bombardier, Claire, Weinblatt, Michael E, van der Heijde, Désirée, Erdmann, Erland, Laine, Loren

“…Cyclo-oxygenase-2 (COX-2) selective inhibitors have been associated with an increased risk of thrombotic cardiovascular events in placebo-controlled trials,…”
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How Common Is Diclofenac-Associated Liver Injury? Analysis of 17,289 Arthritis Patients in a Long-Term Prospective Clinical Trial by LAINE, Loren, GOLDKIND, Lawrence, CURTIS, Sean P, CONNORS, Laurine G, ZHANG YANQIONG, CANNON, Christoper P

“…Few data are available from prospective trials to define the hepatotoxicity of diclofenac, the most widely prescribed non-steroidal anti-inflammatory drug…”
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Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489] by Curtis, Sean P, Bockow, Barry, Fisher, Chester, Olaleye, Joseph, Compton, Amy, Ko, Amy T, Reicin, Alise S

“…The aim of this study was to evaluate the long-term efficacy and tolerability of etoricoxib, a COX-2 selective inhibitor, in osteoarthritis (OA) patients. A…”
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Lung eQTLs to help reveal the molecular underpinnings of asthma by Hao, Ke, Bossé, Yohan, Nickle, David C, Paré, Peter D, Postma, Dirkje S, Laviolette, Michel, Sandford, Andrew, Hackett, Tillie L, Daley, Denise, Hogg, James C, Elliott, W Mark, Couture, Christian, Lamontagne, Maxime, Brandsma, Corry-Anke, van den Berge, Maarten, Koppelman, Gerard, Reicin, Alise S, Nicholson, Donald W, Malkov, Vladislav, Derry, Jonathan M, Suver, Christine, Tsou, Jeffrey A, Kulkarni, Amit, Zhang, Chunsheng, Vessey, Rupert, Opiteck, Greg J, Curtis, Sean P, Timens, Wim, Sin, Don D

“…Genome-wide association studies (GWAS) have identified loci reproducibly associated with pulmonary diseases; however, the molecular mechanism underlying these…”
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Clinical trial design and patient demographics of the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) Study Program: Cardiovascular outcomes with etoricoxib versus diclofenac in patients with osteoarthritis and rheumatoid arthritis by Cannon, Christopher P., Curtis, Sean P., Bolognese, James A., Laine, Loren

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently needed for the treatment of patients with arthritis. However, long-term use of such drugs that are…”
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Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib : results from the MEDAL study by KRUM, Henry, SWERGOLD, Gary, CURTIS, Sean P, KAUR, Amarjot, HONGWEI WANG, SMUGAR, Steven S, WEIR, Matthew R, LAINE, Loren, BRATER, D. Craig, CANNON, Christopher P

“…To evaluate the hypertensive effects of etoricoxib and diclofenac relative to baseline hypertension risk factors in arthritis patients. Multivariate analysis…”
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Perioperative use of etoricoxib reduces pain and opioid side-effects after total abdominal hysterectomy: a double-blind, randomized, placebo-controlled phase III study by Viscusi, Eugene R., Frenkl, Tara L., Hartrick, Craig T., Rawal, Narinder, Kehlet, Henrik, Papanicolaou, Dimitris, Gammaitoni, Arnold, Ko, Amy T., Morgan, Leslie M., Mehta, Anish, Curtis, Sean P., Peloso, Paul M.

“…Abstract Objective: To evaluate the effects of two different doses of etoricoxib delivered perioperatively compared with placebo and standard pain management…”
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Evaluation of NT-proBNP and High Sensitivity C-Reactive Protein for Predicting Cardiovascular Risk in Patients with Arthritis Taking Longterm Nonsteroidal Antiinflammatory Drugs by RUFF, Christian T, MORROW, David A, JAROLIM, Peter, FANG REN, CONTANT, Charles F, KAUR, Amarjot, CURTIS, Sean P, LAINE, Loren, CANNON, Christopher P, BRUNE, Kay

“…Patients with arthritis frequently are at increased risk for future cardiovascular (CV) events. We investigated the performance of the cardiac biomarkers…”
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Human Immunodeficiency Virus Type 1 Gag Polyprotein Multimerization Requires the Nucleocapsid Domain and RNA and Is Promoted by the Capsid-Dimer Interface and the Basic Region of Matrix Protein by Burniston, M T, Cimarelli, A, Colgan, J, Curtis, S P, Luban, J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evaluation of the efficacy and safety of etoricoxib in the treatment of hemophilic arthropathy by Tsoukas, Christos, Eyster, M. Elaine, Shingo, Sumiko, Mukhopadhyay, Saurabh, Giallella, Karen M., Curtis, Sean P., Reicin, Alise S., Melian, Agustin

“…This 2-part, double-blind, placebo-controlled study was conducted to determine the safety and efficacy of etoricoxib, a COX-2 selective inhibitor, for the…”
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Blood pressure and cardiovascular outcomes in patients taking nonsteroidal antiinflammatory drugs by Krum, Henry, Swergold, Gary, Gammaitoni, Arnold, Peloso, Paul M, Smugar, Steven S, Curtis, Sean P, Brater, D Craig, Wang, Hongwei, Kaur, Amarjot, Laine, Loren, Weir, Matthew R, Cannon, Christopher P

“…The increased thrombotic cardiovascular (CV) risk in trials of cyclo-oxygenase-2 (COX-2) inhibitors versus placebo, and the apparent similar risk with…”
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The incidence of upper gastrointestinal adverse events in clinical trials of etoricoxib vs. non-selective NSAIDs: an updated combined analysis by Ramey, Dena R., Watson, Douglas J., Yu, Chang, Bolognese, James A., Curtis, Sean P., Reicin, Alise S.

“…Objective: In spite of numerous studies demonstrating the serious gastrointestinal (GI) toxicity associated with non-selective non-steroidal anti-inflammatory…”
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Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program by Krum, Henry, Curtis, Sean P., Kaur, Amarjot, Wang, Hongwei, Smugar, Steven S., Weir, Matthew R., Laine, Loren, Brater, D. Craig, Cannon, Christopher P.

“…Aims Non-steroidal anti-inflammatory drugs have been associated with increased risk of congestive heart failure (CHF). We aimed to assess the impact of…”
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