Search Results - "Curtis, Lauren M."

A randomized phase 2 trial of pomalidomide in subjects failing prior therapy for chronic graft-versus-host disease by Curtis, Lauren M., Ostojic, Alen, Venzon, David J., Holtzman, Noa G., Pirsl, Filip, Kuzmina, Zoya J., Baird, Kristin, Rose, Jeremy J., Cowen, Edward W., Mays, Jacqueline W., Mitchell, Sandra A., Parsons-Wandell, Laura, Joe, Galen O., Comis, Leora E., Berger, Ann, Pusic, Iskra, Peer, Cody J., Figg, William D., Cao, Liang, Gale, Robert Peter, Hakim, Frances T., Pavletic, Steven Z.

“…Steroid-refractory chronic graft-versus-host disease (cGVHD) is a therapeutic challenge. Sclerotic skin manifestations are especially difficult to treat. We…”
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Impact of the 2014 NIH chronic graft-versus-host disease scoring criteria modifications assessed in a large cohort of severely affected patients by Kerep, Ana Zelic, Broome, Jacob, Pirsl, Filip, Curtis, Lauren M., Steinberg, Seth M., Mitchell, Sandra A., Cowen, Edward W., Pichard, Dominique C., Joe, Galen O., Comis, Leora E., Mays, Jacqueline W., Datiles, Manuel B., Stratton, Pamela, Zolton, Jessica, Berger, Ann, Hendricks, Jennifer, Kenyon, Megan, Baruffaldi, Judy, Titarenko, Irina, Pulanic, Drazen, Baird, Kristin, Fowler, Daniel H., Gress, Ronald E., Pavletic, Steven Z.

“…In 2005, the National Institutes of Health (NIH) chronic graft-versus-host disease (cGVHD) consensus project provided diagnosis and staging criteria, based…”
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Predictive models for ocular chronic graft-versus-host disease diagnosis and disease activity in transplant clinical practice by Curtis, Lauren M, Datiles, 3rd, Manuel B, Steinberg, Seth M, Mitchell, Sandra A, Bishop, Rachel J, Cowen, Edward W, Mays, Jacqueline, McCarty, John M, Kuzmina, Zoya, Pirsl, Filip, Fowler, Daniel H, Gress, Ronald E, Pavletic, Steven Z

“…Ocular chronic graft-versus-host disease is one of the most bothersome common complications following allogeneic hematopoietic stem cell transplantation. The…”
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Achalasia in a Patient Undergoing Hematologic Stem Cell Transplant After Exposure to Tacrolimus by Goklemez, Sencer, Curtis, Lauren M., Hawwa, Alao, Ling, Alexander, Avila, Daniele, Heller, Theo, Pavletic, Steven Z.

“…Calcineurin inhibitors (CNIs) are effective agents used for prevention of graft-vs-host disease after allogeneic hematopoietic stem cell transplant or for…”
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IL-2, the next best thing in chronic GVHD therapy? by Curtis, Lauren M., Pavletic, Steven Z.

“…In this issue of Blood , Koreth et al have reported that interleukin-2 (IL-2) is effective in chronic graft-versus-host disease (cGVHD) patients who had failed…”
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Clinical characteristics and cytokine biomarkers in patients with chronic graft‐vs‐host disease persisting seven or more years after diagnosis by Goklemez, Sencer, Im, Annie P., Cao, Liang, Pirsl, Filip, Steinberg, Seth M., Curtis, Lauren M., Mitchell, Sandra A., Cowen, Edward W., Baruffaldi, Judy, Rose, Jeremy, Mays, Jacqueline, Ostojic, Alen, Holtzman, Noa G., Hakim, Frances T., Pavletic, Steven Z.

“…Chronic graft‐versus‐host disease (cGVHD) is the leading late complication after allogeneic hematopoietic stem cell transplantation (HSCT). Many patients…”
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Predictors of hematologic malignancy relapse in patients with advanced chronic graft-versus-host disease by Ruben, Claire L., Pirsl, Filip, Steinberg, Seth M., Holtzman, Noa G., Parsons-Wandell, Laura, Baruffaldi, Judy, Curtis, Lauren M., Mitchell, Sandra A., Kerep, Ana Zelic, Cowen, Edward W., Berger, Ann, Joe, Galen O., Datiles, Manuel B., Mays, Jacqueline W., Pavletic, Steven Z.

“…Malignancy relapse remains a major barrier to treatment success in patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Chronic…”
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High-dose alemtuzumab and cyclosporine vs tacrolimus, methotrexate, and sirolimus for chronic graft-versus-host disease prevention by Holtzman, Noa G., Curtis, Lauren M., Salit, Rachel B., Shaffer, Brian C., Pirsl, Filip, Ostojic, Alen, Steinberg, Seth M., Schulz, Eduard, Wilder, Jennifer S., Hughes, Thomas E., Rose, Jeremy, Memon, Sarfraz, Korngold, Robert, Gea-Banacloche, Juan C., Fowler, Daniel H., Hakim, Frances T., Gress, Ronald E., Bishop, Michael R., Pavletic, Steven Z.

“…•High-dose alemtuzumab led to effective suppression of cGVHD.•Lymphodepletion delays naive T cell (Tn) recovery resulting in lower T-cell receptor repertoire…”
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Clinical significance of IgE in a large cohort of patients with moderate or severe chronic graft‐versus‐host disease by Goklemez, Sencer, Pirsl, Filip, Curtis, Lauren M., Steinberg, Seth M., Cowen, Edward W., Mays, Jacqueline W., Kenyon, Meg, Baruffaldi, Judy, Hakim, Fran T., Pavletic, Steven Z.

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Vitamin D levels and their associations with survival and major disease outcomes in a large cohort of patients with chronic graft-vs-host disease by Katić, Mašenjka, Pirsl, Filip, Steinberg, Seth M, Dobbin, Marnie, Curtis, Lauren M, Pulanić, Dražen, Desnica, Lana, Titarenko, Irina, Pavletic, Steven Z

“…To identify the factors associated with vitamin D status in patients with chronic graft-vs-host disease (cGVHD) and evaluate the association between serum…”
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Impaired Bone Mineral Density in Pediatric Patients with Chronic Graft-versus-Host Disease by Buxbaum, Nataliya P., Robinson, Cemre, Sinaii, Ninet, Ling, Alexander, Curtis, Lauren M., Pavletic, Steven Z., Baird, Kristin, Lodish, Maya B.

“…•Children with cGVHD are at a greater risk for BMD impairment than previously appreciated.•More than 70% of the patients in our cohort had a DEXA z-score ≤−2…”
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Characterization and Risk Factor Analysis of Osteoporosis in a Large Cohort of Patients with Chronic Graft-versus-Host Disease by Pirsl, Filip, Curtis, Lauren M, Steinberg, Seth M, Tella, Sri Harsha, Katić, Mašenjka, Dobbin, Marnie, Hsu, Jennifer, Hakim, Fran T, Mays, Jacqueline W, Im, Annie P, Pulanić, Dražen, Mitchell, Sandra A, Baruffaldi, Judy, Masuch, Licia, Halverson, David C, Gress, Ronald E, Barsony, Julianna, Pavletic, Steven Z

“…Abstract The National Institutes of Health Chronic Graft-versus-Host Disease (cGVHD) Consensus Project Ancillary and Supportive Care Guidelines recommend…”
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Predictors for Permanent Discontinuation of Systemic Immunosuppression in Severely Affected Chronic Graft-Versus-Host Disease Patients by Curtis, Lauren M., Pirsl, Filip, Steinberg, Seth M., Mitchell, Sandra A., Baird, Kristin, Cowen, Edward W., Mays, Jacqueline, Buxbaum, Nataliya P., Pichard, Dominique C., Im, Annie, Avila, Daniele, Taylor, Tiffani, Fowler, Daniel H., Gress, Ronald E., Pavletic, Steven Z.

“…•The cumulative incidence of systemic therapy discontinuation was 27.7% (95% confidence interval, 20.9% to 34.8%) by 5 years.•Factors associated with a higher…”
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Allogeneic Bone Marrow Transplantation for Primary Immunodeficiencies: Pilot Trial of a Novel, Reduced Intensity Platform by Dimitrova, Dimana, Gea-Banacloche, Juan, Freeman, Alexandra F, Uzel, Gulbu, Zerbe, Christa, Cohen, Jeffrey I, Rao, V. Koneti, Holland, Steven M, Cotton, Stephanie, Mann, Jennifer, Skeffington, Lauren, Curtis, Lauren M, Pavletic, Steven Z, Fowler, Daniel, Gress, Ronald E, Kanakry, Christopher G, Kanakry, Jennifer A

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Th17 Recruitment and Interferon Pathway Activation in Oral Chronic Graft-Versus-Host Disease Tissues by Mays, Jacqueline W., DDS, MHS, PhD, Weller, Melodie L., PhD, Bassim, Carol W., DMD, MHS, Dhamala, Susan, BS, Curtis, Lauren M., MD, Rose, Jeremy J., MS, Pavletic, Steven Z., MD, Hakim, Fran T., PhD

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Preconditioning Single High-Dose Palifermin Alters the Posttransplant Inflammatory Cytokine Profile by Schulz, Eduard, Holtzman, Noa G., Ostojic, Alen, Pirsl, Filip, Steinberg, Seth M., Curtis, Lauren M., Shaffer, Brian C., Heller, Theo, Carpenter, Ashley, Hakim, Frances T., Rubin, Jeffrey S., Pavletic, Steven Z.

“…Palifermin is a truncated form of human recombinant keratinocyte growth factor (KGF) that binds to the FGF receptor 2b expressed in epithelia including that of…”
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Predictors for Permanent Discontinuation of Systemic Immunosuppression in Patients with Moderate to Severe Chronic Graft-Versus-Host-Disease by Curtis, Lauren M., MD, Pirsl, Filip, B.Sc, Hsu, Jennifer, RN, Steinberg, Seth M., PhD, Mitchell, Sandra A., PhD, CRNP, Masuch, Licia, Im, Annie, MD, Baruffaldi, Judy L., BA, Mays, Jacqueline, DDS, Halverson, David, MD, Fowler, Daniel, MD, Gress, Ronald, MD, Pavletic, Steven Z., MD

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Effects of Alvelestat, an Oral Neutrophil Elastase Inhibitor, on Elevated Elastase and Collagen Turnover Biomarkers in Patients with Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation by Im, Annie, Parkin, Jacqueline, Holtzman, Noa G., Moore, William, Curtis, Lauren M., Peer, Cody, Figg, William D., Rose, Jeremy J., Parsons-Wandell, Laura, Hakim, Frances T., Pavletic, Steven Z.

“…Introduction Bronchiolitis Obliterans Syndrome (BOS) is a rare but devastating complication of chronic graft-versus-host disease (GVHD) after allogeneic…”
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High Incidence of Osteoporosis in a Natural History Cohort of Patients with Moderate to Severe Chronic Graft-Versus-Host Disease and Risk Factor Analysis by Pirsl, Filip, B.Sc, Curtis, Lauren M., MD, Steinberg, Seth M., PhD, Katic, Masenjka, MS, Dobbin, Marnie, MS, RD, Hsu, Jennifer, RN, Avila, Daniele, CRNP, Taylor, Tiffani, PA-C, Baruffaldi, Judy L., BA, Barsony, Julianna, MD, Pavletic, Steven Z., MD

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Leukapheresis Safely and Effectively Yields Lymphocyte Populations Sufficient for Chronic Gvhd Research by Curtis, Lauren M., MD, Cantilena, Cathy, MD, Yau, Yu Ying, RN, Chinn, Tracey, RN, Hsu, Jennifer, RN, Pirsl, Filip, B.Sc, Baruffaldi, Judy L., BA, Hakim, Fran, PhD, Fowler, Daniel, MD, Gress, Ronald, MD, Pavletic, Steven Z., MD

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