Search Results - "Curtet, Sandrine"
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Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters
Published in Molecular cell (21-04-2016)“…Recently discovered histone lysine acylation marks increase the functional diversity of nucleosomes well beyond acetylation. Here, we focus on histone…”
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A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
Published in Nature communications (19-12-2016)“…Bromodomains are critical components of many chromatin modifying/remodelling proteins and are emerging therapeutic targets, yet how they interact with…”
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Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
Published in Nature (London) (01-10-2009)“…A key step in many chromatin-related processes is the recognition of histone post-translational modifications by effector modules such as bromodomains and…”
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Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
Published in Genes & development (01-08-2013)“…The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental to the life cycle, yet the underlying molecular details remain…”
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
Published in Cell reports (Cambridge) (27-07-2021)“…In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and co-exist…”
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Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells
Published in Journal of molecular cell biology (01-08-2016)“…Although the conserved AAA ATPase and bromodomain factor, ATAD2, has been described as a transcriptional co-activator upregulated in many cancers, its function…”
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Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like Structures
Published in Cell reports (Cambridge) (01-12-2015)“…Protamines confer a compact structure to the genome of male gametes. Here, we find that somatic cells can be remodeled by transient expression of protamine 1…”
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RNA-Guided Genomic Localization of H2A.L.2 Histone Variant
Published in Cells (Basel, Switzerland) (18-02-2020)“…The molecular basis of residual histone retention after the nearly genome-wide histone-to-protamine replacement during late spermatogenesis is a critical and…”
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Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways
Published in Molecular and Cellular Biology (01-12-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm
Published in Current biology (15-06-2000)“…The intracellular localization, and thereby the function, of a number of key regulator proteins tagged with a short leucine-rich motif (the nuclear export…”
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mHDA1/HDAC5 Histone Deacetylase Interacts with and Represses MEF2A Transcriptional Activity
Published in The Journal of biological chemistry (19-05-2000)“…Recently we identified a new family of histone deacetylases in higher eukaryotes related to yeast HDA1 and showed their differentiation-dependent expression…”
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Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells
Published in Molecular cell (06-04-2017)“…Histone replacement by transition proteins (TPs) and protamines (Prms) constitutes an essential step for the successful production of functional male gametes,…”
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Bromodomain-dependent stage-specific male genome programming by Brdt
Published in The EMBO journal (03-10-2012)“…Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major…”
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Site-Specific Introduction of an Acetyl-Lysine Mimic into Peptides and Proteins by Cysteine Alkylation
Published in Journal of the American Chemical Society (28-07-2010)“…Protein acetylation on Lys residues is recognized as a significant post-translational modification in cells, but it is often difficult to discern the direct…”
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Differential Recognition of Histone H10 by Monoclonal Antibodies during Cell Differentiation and the Arrest of Cell Proliferation
Published in The Journal of biological chemistry (09-01-1998)“…Individual anti-H10 monoclonal antibodies were screened in an immunolocalization assay to isolate clones able to recognize H10 in a differentiation-dependent…”
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Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies
Published in Antioxidants & redox signaling (01-07-2015)“…Ectopic activation of tissue-specific genes accompanies malignant transformation in many cancers. Prolactin (PRL) aberrant activation in lung cancer was…”
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Bromodomain-dependent stage-specific male genome programming by Brdt: Brdt: a master regulator of spermatogenesis
Published in The EMBO journal (03-10-2012)“…Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major…”
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Molecular models for post-meiotic male genome reprogramming
Published in Systems biology in reproductive medicine (01-02-2011)“…The molecular basis of post-meiotic male genome reorganization and compaction constitutes one of the last black boxes in modern biology. Although the…”
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Cooperative binding of two acetylation marks on a histone tail bv a single bromodomain
Published in Nature (London) (2009)Get full text
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