Search Results - "Cursley, Adam"

A retrospective observational study to evaluate the clinical outcomes and routine management of patients with chronic lymphocytic leukaemia treated with idelalisib and rituximab in the UK and Ireland (RETRO‐idel) by Eyre, Toby A., Preston, Gavin, Kagdi, Huseini, Islam, Amin, Nicholson, Toby, Smith, Harry W., Cursley, Adam P., Ramroth, Heribert, Xing, Guan, Gu, Lin, Rajakumaraswamy, Nishanthan, Fegan, Christopher

“…Summary Idelalisib (IDL) is an oral first‐in‐class phosphatidylinositol 3‐kinase delta (PI3Kδ) inhibitor approved for chronic lymphocytic leukaemia (CLL)…”
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A Multicentre, Retrospective Observational Study to Evaluate the Clinical Outcomes of Patients with Chronic Lymphocytic Leukaemia (CLL) Treated with Idelalisib and Rituximab in the UK (RETRO-idel) - a Cohort of 110 Patients by Eyre, Toby A., Preston, Gavin, Kagdi, Huseini Hatimbhai, Islam, Amin, Nicholson, Toby, Fegan, Christopher, Smith, Harry W, Cursley, Adam P, Ramroth, Heribert, Rajakumaraswamy, Nishan

“…Background: B-cell receptor signalling pathway plays a key role in CLL pathogenesis. Overexpression of phosphatidylinositol 3-kinase delta isoform (PI3Kδ) is a…”
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Influence of UGT1A1 and SLC22A6 polymorphisms on the population pharmacokinetics and pharmacodynamics of raltegravir in HIV-infected adults: a NEAT001/ANRS143 sub-study by Gurjar, Rohan, Dickinson, Laura, Carr, Daniel, Stöhr, Wolfgang, Bonora, Stefano, Owen, Andrew, D’Avolio, Antonio, Cursley, Adam, De Castro, Nathalie, Fätkenheuer, Gerd, Vandekerckhove, Linos, Di Perri, Giovanni, Pozniak, Anton, Schwimmer, Christine, Raffi, François, Boffito, Marta

“…Using concentration-time data from the NEAT001/ARNS143 study (single sample at week 4 and 24), we determined raltegravir pharmacokinetic parameters using…”
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Patient-Reported Outcomes in First-Line Antiretroviral Therapy: Results From NEAT001/ANRS143 Trial Comparing Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine or Raltegravir by George, Elizabeth C, Bucciardini, Raffaella, Richert, Laura, Dedes, Nikos, Fragola, Vincenzo, Nieuwkerk, Pythia, Spire, Bruno, Volny-Anne, Alain, West, Brian, Molina, Jean-Michel, Horban, Andrzej, Fox, Julie, Pozniak, Anton, Vella, Stefano, Termote, Monique, Raffi, François

“…BACKGROUND:There are few data comparing patient-reported outcomes (PROs) in randomized trials of initial antiretroviral therapy. We present results from a…”
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Comparison of the Outcomes of Individuals With Medically Attended Influenza A and B Virus Infections Enrolled in 2 International Cohort Studies Over a 6-Year Period: 2009–2015 by Dwyer, Dominic E, Lynfield, Ruth, Losso, Marcelo H, Davey, Richard T, Cozzi-Lepri, Alessandro, Wentworth, Deborah, Uyeki, Timothy M, Gordin, Fred, Angus, Brian, Qvist, Tavs, Emery, Sean, Lundgren, Jens, Neaton, James D

“…Abstract Background Outcome data from prospective follow-up studies comparing infections with different influenza virus types/subtypes are limited. Methods…”
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