Search Results - "Cursio, Raffaele"

Autophagy and Liver Ischemia-Reperfusion Injury by Cursio, Raffaele, Gugenheim, Jean, Colosetti, Pascal

“…Liver ischemia-reperfusion (I-R) injury occurs during liver resection, liver transplantation, and hemorrhagic shock. The main mode of liver cell death after…”
Get full text

Ischemia-Reperfusion Injury and Ischemic-Type Biliary Lesions following Liver Transplantation by Cursio, Raffaele, Gugenheim, Jean

“…Ischemia-reperfusion (I-R) injury after liver transplantation (LT) induces intra- and/or extrahepatic nonanastomotic ischemic-type biliary lesions (ITBLs)…”
Get full text

A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis by CURSIO, RAFFAELE, GUGENHEIM, JEAN, RICCI, JEAN EHRLAND, CRENESSE, DOMINIQUE, ROSTAGNO, PHILIPPE, MAULON, LAURENCE, SAINT-PAUL, MARIE-CHRISTINE, FERRUA, BERNARD, AUBERGER, PATRICK

“…ABSTRACT Apoptosis is activated during the early phase of reperfusion after liver ischemia and after liver transplantation in animals. However, the molecular…”
Get full text

Rat liver injury following normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor by Cursio, Raffaele, Mari, Bernard, Louis, Krystel, Rostagno, Philippe, Saint-Paul, Marie-Christine, Giudicelli, Jean, Bottero, Virginie, Anglard, Patrick, Yiotakis, Athanasios, Dive, Vincent, Gugenheim, Jean, Auberger, Patrick

“…Hepatic ischemia occurs in liver transplantation, hemodynamic or cardiogenic shock, and liver resection associated with trauma or tumor. Ischemia/reperfusion…”
Get full text

Rat liver ischemia–reperfusion-induced apoptosis and necrosis are decreased by FK506 pretreatment by Crenesse, Dominique, Laurens, Marina, Heurteaux, Catherine, Cursio, Raffaele, Saint-Paul, Marie Christine, Schmid-Alliana, Annie, Gugenheim, Jean

“…The aim of this study was to demonstrate that tacrolimus (FK506) has a hepatoprotective effect by reducing ischemia–reperfusion-induced apoptosis and necrosis,…”
Get full text

Caspase inhibition in liver transplantation: from basic research to clinical studies by Cursio, Raffaele

Get full text

The Role of Autophagy in Liver Diseases: Mechanisms and Potential Therapeutic Targets by Cursio, Raffaele, Colosetti, Pascal, Codogno, Patrice, Cuervo, Ana Maria, Shen, Han-Ming

Get full text

Diltiazem reduces apoptosis in rat hepatocytes subjected to warm hypoxia-reoxygenation by Crenesse, Dominique, Tornieri, Karine, Laurens, Marina, Heurteaux, Catherine, Cursio, Raffaele, Gugenheim, Jean, Schmid-Alliana, Annie

“…Interruption of hepatic blood flow is necessary in surgery, but the liver is sensitive to ischemia and reperfusion. Hypoxia induces an increase in…”
Get more information

Rat liver injury after normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor by Cursio, Raffaele, Mari, Bernard, Louis, Krystel, Rostagno, Philippe, Saint-Paul, Marie-Christine, Giudicelli, Jean, Bottero, Virginie, Anglard, Patrick, Yiotakis, Athanasios, Dive, Vincent, Gugenheim, Jean, Auberger, Patrick

“…Hepatic ischemia occurs in liver transplantation, hemodynamic or cardiogenic shock, and liver resection associated with trauma or tumor. Ischemia/reperfusion…”
Get full text

Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver by Cursio, Raffaele, Miele, Claudia, Filippa, Nathalie, Colosetti, Pascal, Auberger, Patrick, Van Obberghen, Emmanuel, Gugenheim, Jean

“…Background Phosphoregulation of signal transduction pathways is a complex series of reactions that may modulate the cellular response to ischemia–reperfusion…”
Get full text

Intermittent ischemia reduces warm hypoxia-reoxygenation–induced JNK1/SAPK1 activation and apoptosis in rat hepatocytes by Crenesse, Dominique, Laurens, Marina, Gugenheim, Jean, Heurteaux, Catherine, Cursio, Raffaele, Rossi, Bernard, Schmid-Alliana, Annie

“…Prolonged liver ischemia followed by reperfusion (I/R) causes functional and structural damage to liver cells, resulting in necrosis and apoptosis. c-jun…”
Get full text

Pentoxifylline inhibits liver expression of tumor necrosis factor alpha mRNA following normothermic ischemia-reperfusion by El-Ghoneimi, Alaa, Cursio, Raffaele, Schmid-Alliana, Annie, Tovey, Michel, Lasfar, Ahmed, Michiels, Jean-Francois, Rossi, Bernard, Gugenheim, Jean

“…Background: Pentoxifylline (PTX) has been shown to reduce hepatic injury after normothermic ischemia and reperfusion (I-R) in rat liver. Aim: The aim of this…”
Get full text

Fas Ligand Expression Following Normothermic Liver Ischemia-Reperfusion by Cursio, Raffaele, Filippa, Nathalie, Miele, Claudia, Colosetti, Pascal, Auberger, Patrick, Van Obberghen, Emmanuel, Gugenheim, Jean

“…The aim of this study was to evaluate the role of the pro-apoptotic molecule Fas Ligand (FasL) in 120 min normothermic ischemia-reperfusion (I-R) induced…”
Get full text

Effect of Caspase Inhibition on Thymic Apoptosis in Hemorrhagic Shock by Bini, Roberto, Cursio, Raffaele, Belhacene, Nathalie, Giudicelli, Jean, Ferruà, Bernard, Olivero, Giorgio, Auberger, Patrick, Mari, Bernard, Gugenheim, Jean, Cotogni, Paolo

“…In hemorrhagic shock (HS) an increased thymic apoptosis (TA) was described. The aim of this study was to evaluate the effect of administration of the caspase…”
Get full text

Intestinal lactase-phlorizin hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation by Zecca, Laura, Mesonero, José E, Stutz, Alfred, Poirée, Jean-Claude, Giudicelli, Jean, Cursio, Raffaele, Gloor, Sergio M, Semenza, Giorgio

“…Brush border lactase-phlorizin hydrolase carries two catalytic sites. In the human enzyme lactase comprises Glu-1749, phlorizin hydrolase Glu-1273. The…”
Get full text

Increased Risk of Antibody-Mediated Rejection of Reduced-Size Liver Allografts by Astarcioglu, Ibraõm, Cursio, Raffaele, Reynes, Michel, Gugenheim, Jean

“…Because of the shortage of liver allografts in children, transplantation of reduced-size liver allografts from adult cadaveric donors or living, related donors…”
Get full text

Consequences of adrenalectomy on small intestine trophic parameters in aged and young rats evidence of defective adaptation by aging and lack of corticoids by FOLIGNE, Benoit, SENEGAS-BALAS, Francoise, CURSIO, Raffaele, CAYUELA, Chantal, ANTOINE, Jean-Michel, ROLF-PETERSEN, Nathalie, BALAS, Daniel

“…Previous study pointed to an important role of adrenals and glucocorticoids in the trophic status of the adult small intestine mucosa, with possible…”
Get full text

Improvement of Normothermic Rat Liver Ischemia/Reperfusion by Muramyl Dipeptide by Cursio, Raffaele, Gugenheim, Jean, Panaia-Ferrari, Patricia, Lasfar, Ahmed, Tovey, Michael, Chastanet, Sylvain, Saint-Paul, Marie Christine, Ferré, Catherine, Mouiel, Jean

“…Normothermic ischemia and reperfusion (I/R) of the liver remains a major problem after liver surgery and transplantation. Activation of Kupffer cells (KCs)…”
Get full text