Search Results - "Curry, Heather"

Functional landscape of SARS-CoV-2 cellular restriction by Martin-Sancho, Laura, Lewinski, Mary K., Pache, Lars, Stoneham, Charlotte A., Yin, Xin, Becker, Mark E., Pratt, Dexter, Churas, Christopher, Rosenthal, Sara B., Liu, Sophie, Weston, Stuart, De Jesus, Paul D., O’Neill, Alan M., Gounder, Anshu P., Nguyen, Courtney, Pu, Yuan, Curry, Heather M., Oom, Aaron L., Miorin, Lisa, Rodriguez-Frandsen, Ariel, Zheng, Fan, Wu, Chunxiang, Xiong, Yong, Urbanowski, Matthew, Shaw, Megan L., Chang, Max W., Benner, Christopher, Hope, Thomas J., Frieman, Matthew B., García-Sastre, Adolfo, Ideker, Trey, Hultquist, Judd F., Guatelli, John, Chanda, Sumit K.

“…A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been implicated as a determinant of severe…”
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Fine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensis by Dai, Shipan, Rajaram, Murugesan V S, Curry, Heather M, Leander, Rachel, Schlesinger, Larry S

“…Complement receptor 3 (CR3, CD11b/CD18) is a major macrophage phagocytic receptor. The biochemical pathways through which CR3 regulates immunologic responses…”
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Review of cone beam computed tomography based online adaptive radiotherapy: current trend and future direction by Liu, Hefei, Schaal, David, Curry, Heather, Clark, Ryan, Magliari, Anthony, Kupelian, Patrick, Khuntia, Deepak, Beriwal, Sushil

“…Adaptive radiotherapy (ART) was introduced in the late 1990s to improve the accuracy and efficiency of therapy and minimize radiation-induced toxicities. ART…”
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Adoption of Hypofractionated Radiation Therapy for Breast Cancer After Publication of Randomized Trials by Jagsi, Reshma, MD, DPhil, Falchook, Aaron D., MD, Hendrix, Laura H., MS, Curry, Heather, MD, Chen, Ronald C., MD, MPH

“…Purpose Large randomized trials have established the noninferiority of shorter courses of “hypofractionated” radiation therapy (RT) to the whole breast…”
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Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA by Yoh, Sunnie M., Mamede, João I., Lau, Derrick, Ahn, Narae, Sánchez-Aparicio, Maria T., Temple, Joshua, Tuckwell, Andrew, Fuchs, Nina V., Cianci, Gianguido C., Riva, Laura, Curry, Heather, Yin, Xin, Gambut, Stéphanie, Simons, Lacy M., Hultquist, Judd F., König, Renate, Xiong, Yong, García-Sastre, Adolfo, Böcking, Till, Hope, Thomas J., Chanda, Sumit K.

“…We have previously described polyglutamine-binding protein 1 (PQBP1) as an adapter required for the cyclic GMP-AMP synthase (cGAS)-mediated innate response to…”
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Metformin selectively targets redox control of complex I energy transduction by Cameron, Amy R., Logie, Lisa, Patel, Kashyap, Erhardt, Stefan, Bacon, Sandra, Middleton, Paul, Harthill, Jean, Forteath, Calum, Coats, Josh T., Kerr, Calum, Curry, Heather, Stewart, Derek, Sakamoto, Kei, Repiščák, Peter, Paterson, Martin J., Hassinen, Ilmo, McDougall, Gordon, Rena, Graham

“…Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical…”
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Correction: Fine Tuning Inflammation at the Front Door: Macrophage Complement Receptor 3-mediates Phagocytosis and Immune Suppression for Francisella tularensis by Dai, Shipan, Rajaram, Murugesan V S, Curry, Heather M, Leander, Rachel, Schlesinger, Larry S

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AR-13, a Celecoxib Derivative, Directly Kills Francisella In Vitro and Aids Clearance and Mouse Survival In Vivo by Hoang, Ky V, Adcox, Haley E, Fitch, James R, Gordon, David M, Curry, Heather M, Schlesinger, Larry S, White, Peter, Gunn, John S

“…( ) is the causative agent of tularemia and is classified as a Tier 1 select agent. No licensed vaccine is currently available in the United States and…”
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Mycobacteria inhibition of IFN-gamma induced HLA-DR gene expression by up-regulating histone deacetylation at the promoter region in human THP-1 monocytic cells by Wang, Yue, Curry, Heather M, Zwilling, Bruce S, Lafuse, William P

“…Infection of macrophages with mycobacteria has been shown to inhibit the macrophage response to IFN-gamma. In the current study, we examined the effect of…”
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Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent by Chiu, Hao-Chieh, Soni, Shilpa, Kulp, Samuel K, Curry, Heather, Wang, Dasheng, Gunn, John S, Schlesinger, Larry S, Chen, Ching-Shih

“…Autophagy has been shown recently to play an important role in the intracellular survival of several pathogenic bacteria. In this study, we investigated the…”
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Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes by Gillette, Devyn D, Curry, Heather M, Cremer, Thomas, Ravneberg, David, Fatehchand, Kavin, Shah, Prexy A, Wewers, Mark D, Schlesinger, Larry S, Butchar, Jonathan P, Tridandapani, Susheela, Gavrilin, Mikhail A

“…Human monocyte inflammatory responses differ between virulent and attenuated Francisella infection. A mixed infection model showed that the virulent F…”
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Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines by Zoberi, Imran, Bradbury, C.Matthew, Curry, Heather A., Bisht, Kheem S., Goswami, Prabhat C., Roti Roti, Joseph L., Gius, David

“…Resveratrol is a polyphenol isolated from the skins of grapes that has been shown to significantly alter the cellular physiology of tumor cells, as well as…”
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Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes by Hoang, Ky V, Rajaram, Murugesan V S, Curry, Heather Marie, Gavrilin, Mikhail A, Wewers, Mark D, Schlesinger, Larry S

“…is a remarkably infectious facultative intracellular bacterium of macrophages that causes tularemia. Early evasion of host immune responses contributes to the…”
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Mycobacterium tuberculosis and Mycobacterium avium inhibit IFN- gamma -induced gene expression by TLR2-dependent and independent pathways by Lafuse, William P, Alvarez, Gail R, Curry, Heather M, Zwilling, Bruce S

“…Mycobacteria-infected macrophages are poor responders to interferon-gamma (IFN-gamma), resulting in decreased expression of IFN-gamma-induced genes. In the…”
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RapidPlan hippocampal sparing whole brain model version 2—how far can we reduce the dose? by Liu, Hefei, Clark, Ryan, Magliari, Anthony, Foster, Robert, Reynoso, Francisco, Schmidt, Matthew, Gondi, Vinai, Abraham, Christopher, Curry, Heather, Kupelian, Patrick, Khuntia, Deepak, Beriwal, Sushil

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Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge by Hoang, Ky V, Curry, Heather, Collier, Michael A, Borteh, Hassan, Bachelder, Eric M, Schlesinger, Larry S, Gunn, John S, Ainslie, Kristy M

“…Francisella tularensiscauses tularemia and is a potential biothreat. Given the limited antibiotics for treating tularemia and the possible use of…”
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Influence of aging on the phenotype and function of alveolar macrophages by Lafuse, William P, Rajaram, Murugesan VS, Curry, Heather M, Nealer, Connor, Canan, Cynthia H, Moliva, Juan I, Torrelles, Jordi B, Turner, Joanne, Schlesinger, Larry S

“…Abstract Aging is associated with a decline in immune function (immunosenescence), resulting in increased susceptibility to infectious diseases, malignancies,…”
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Overutilization of IMRT/IGRT in treatment of rectal cancer: Cost implications of deviation from evidence-based practices by Curry, Heather A, Forastiere, Arlene A., Flood, William A., Whyler, Elaine, Plastaras, John Peter, Vapiwala, Neha

“…Abstract only 34 Background: Current evidence-based guidelines for management of rectal cancer (RC) caution against routine use of IMRT and do not address the…”
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SPCR-01 RAPIDPLAN HIPPOCAMPAL SPARING WHOLE BRAIN MODEL VERSION 2 - HOW FAR CAN WE REDUCE THE DOSE? by Liu, Hefei, Clark, Ryan, Magliari, Anthony, Foster, Robert, Reynoso, Francisco, Schmidt, Matthew, Gondi, Vinai, Abraham, Christopher, Curry, Heather, Kupelian, Patrick, Khuntia, Deepak, Beriwal, Sushil

“…Abstract BACKGROUND Whole-brain radiotherapy (WBRT) has been the standard palliative treatment for patients with brain metastases due to its effectiveness,…”
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Full-Contact Pedagogy: Lecturing with Questions and Student-Centered Assignments as Methods for Inciting Self-Reflexivity for Faculty and Students by CRAWLEY, SARA L., CURRY, WITH HEATHER, DUMOIS-SANDS, JULIE, TANNER, CHELSEA, WYKER, CYRANA

“…For this essay, the author takes as an organizing premise Jodi O'Brien and Judith A. Howard's notion of responsible authority--that "teaching is a value-based…”
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