Search Results - "Current pharmaceutical design"

Pathophysiology of Ischemic Stroke: Role of Oxidative Stress by Orellana-Urzúa, Sofía, Rojas, Ignacio, Líbano, Lucas, Rodrigo, Ramón

“…Stroke is the second leading cause of mortality and the major cause of adult physical disability worldwide. The currently available treatment to recanalize the…”
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Oxidative Stress and Cancer by Klaunig, James E

“…Cancer is considered a major cause of death worldwide. The etiology of cancer is linked to environmental and genetic inheritance causes. Approximately 90…”
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Alginate Nanoparticles for Drug Delivery and Targeting by Severino, Patricia, da Silva, Classius F, Andrade, Luciana N, de Lima Oliveira, Daniele, Campos, Joana, Souto, Eliana B

“…Nanotechnology refers to the control, manipulation, study and manufacture of structures and devices at the nanometer size range. The small size, customized…”
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Internet addiction: a systematic review of epidemiological research for the last decade by Kuss, D J, Griffiths, M D, Karila, L, Billieux, J

“…In the last decade, Internet usage has grown tremendously on a global scale. The increasing popularity and frequency of Internet use has led to an increasing…”
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Gelatin as Biomaterial for Tissue Engineering by Echave, Mari C, Saenz del Burgo, Laura, Pedraz, Jose L, Orive, Gorka

“…Tissue engineering is considered one of the most important therapeutic strategies of regenerative medicine. The main objective of these new technologies is the…”
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Synthesis of Silver Nanoparticles and their Biomedical Applications - A Comprehensive Review by Shanmuganathan, Rajasree, Karuppusamy, Indira, Saravanan, Muthupandian, Muthukumar, Harshiny, Ponnuchamy, Kumar, Ramkumar, Vijayan Sri, Pugazhendhi, Arivalagan

“…Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a…”
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Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases by Fiorentino, Teresa Vanessa, Prioletta, Annamaria, Zuo, Pengou, Folli, Franco

“…Diabetes mellitus is associated to an increased risk of cardiovascular diseases. Hyperglycemia is an important factor in cardiovascular damage, working through…”
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Computer Aided Drug Design: Success and Limitations by Baig, Mohammad Hassan, Ahmad, Khurshid, Roy, Sudeep, Ashraf, Jalaluddin Mohammad, Adil, Mohd, Siddiqui, Mohammad Haris, Khan, Saif, Kamal, Mohammad Amjad, Provazník, Ivo, Choi, Inho

“…Over the last few decades, computer-aided drug design has emerged as a powerful technique playing a crucial role in the development of new drug molecules…”
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Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier by Hersh, David S, Wadajkar, Aniket S, Roberts, Nathan, Perez, Jimena G, Connolly, Nina P, Frenkel, Victor, Winkles, Jeffrey A, Woodworth, Graeme F, Kim, Anthony J

“…The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central nervous system (CNS). The BBB consists of a continuous layer of…”
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ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development by Choi, Young Hee, Yu, Ai-Ming

“…Multidrug resistance (MDR) is a serious problem that hampers the success of cancer pharmacotherapy. A common mechanism is the overexpression of ATP-binding…”
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Quorum sensing inhibitors as anti-biofilm agents by Brackman, Gilles, Coenye, Tom

“…Biofilms are microbial sessile communities characterized by cells that are attached to a substratum or interface or to each other, are embedded in a…”
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Hyperuricemia and Cardiovascular Disease by Zhang, Shuangshuang, Wang, Yong, Cheng, Jinsong, Huangfu, Ning, Zhao, Ruochi, Xu, Zhenyu, Zhang, Fuxing, Zheng, Wenyuan, Zhang, Dandan

“…Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and…”
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The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier by Matsumoto, Junichi, Stewart, Tessandra, Banks, William A, Zhang, Jing

“…Recently, extracellular vesicles (EVs), like exosomes and microvesicles, have attracted attention as potent carriers of intercellular communication throughout…”
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Social network site addiction - an overview by Andreassen, Cecilie Schou, Pallesen, Ståle

“…Research into frequent, excessive, and compulsive social network activity has increased the last years, in which terms such as "social network site addiction"…”
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Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature by Giorgini, Paolo, Di Giosia, Paolo, Grassi, Davide, Rubenfire, Melvyn, Brook, Robert D, Ferri, Claudio

“…Both high arterial blood pressure (BP) and elevated levels of fine particulate matter (PM2.5) air pollution have been associated with an increased risk for…”
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Salvia miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases by Wang, Lili, Ma, Rufeng, Liu, Chenyue, Liu, Haixia, Zhu, Ruyuan, Guo, Shuzhen, Tang, Minke, Li, Yu, Niu, Jianzhao, Fu, Min, Gao, Sihua, Zhang, Dongwei

“…Salvia miltiorrhiza Bunge, also known as Danshen in Chinese, has been widely used to treat cardiovascular diseases (CVD) in China and other Asia countries…”
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Curcumin: An Effective Inhibitor of Interleukin-6 by Ghandadi, Morteza, Sahebkar, Amirhossein

“…Curcumin is apolyphenolic compound found in the dietary spice turmeric. Anti-inflammatory effects of turmeric have been known for centuries and extensive…”
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Composition and Potential Health Benefits of Pomegranate: A Review by Vučić, Vesna, Grabež, Milkica, Trchounian, Armen, Arsić, Aleksandra

“…Pomegranate (Punica granatum L.) fruits are widely consumed and used as preventive and therapeutic agents since ancient times. Pomegranate is a rich source of…”
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Ceramic Nanoparticles: Fabrication Methods and Applications in Drug Delivery by Thomas, Shindu C, Harshita, Mishra, Pawan Kumar, Talegaonkar, Sushama

“…Ceramic nanoparticles are primarily made up of oxides, carbides, phosphates and carbonates of metals and metalloids such as calcium, titanium, silicon, etc…”
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Mean platelet volume: a link between thrombosis and inflammation? by Gasparyan, Armen Yuri, Ayvazyan, Lilit, Mikhailidis, Dimitri P, Kitas, George D

“…Platelet activation is a link in the pathophysiology of diseases prone to thrombosis and inflammation. Numerous platelet markers, including mean platelet…”
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