Search Results - "Current issues in molecular biology"

Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications by Caturano, Alfredo, D’Angelo, Margherita, Mormone, Andrea, Russo, Vincenzo, Mollica, Maria Pina, Salvatore, Teresa, Galiero, Raffaele, Rinaldi, Luca, Vetrano, Erica, Marfella, Raffaele, Monda, Marcellino, Giordano, Antonio, Sasso, Ferdinando Carlo

“…Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its associated complications. The imbalance between reactive oxygen…”
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Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line by Aldén, Markus, Olofsson Falla, Francisko, Yang, Daowei, Barghouth, Mohammad, Luan, Cheng, Rasmussen, Magnus, De Marinis, Yang

“…Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the…”
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Next-Generation Sequencing (NGS) in COVID-19: A Tool for SARS-CoV-2 Diagnosis, Monitoring New Strains and Phylodynamic Modeling in Molecular Epidemiology by John, Goldin, Sahajpal, Nikhil Shri, Mondal, Ashis K, Ananth, Sudha, Williams, Colin, Chaubey, Alka, Rojiani, Amyn M, Kolhe, Ravindra

“…This review discusses the current testing methodologies for COVID-19 diagnosis and explores next-generation sequencing (NGS) technology for the detection of…”
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Phage Biocontrol Applications in Food Production and Processing by Vikram, Amit, Woolston, Joelle, Sulakvelidze, Alexander

“…Bacteriophages, or phages, are one of the most, if not the most, ubiquitous organisms on Earth. Interest in various practical applications of bacteriophages…”
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Genistein: A Potent Anti-Breast Cancer Agent by Bhat, Smitha S, Prasad, Shashanka K, Shivamallu, Chandan, Prasad, Kollur Shiva, Syed, Asad, Reddy, Pruthvish, Cull, Charley A, Amachawadi, Raghavendra G

“…Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide range of bioactives, it is being studied extensively for its tumoricidal…”
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Plant Immune System: Crosstalk Between Responses to Biotic and Abiotic Stresses the Missing Link in Understanding Plant Defence by Nejat, Naghmeh, Mantri, Nitin

“…Environmental pollution, global warming and climate change exacerbate the impact of biotic and abiotic stresses on plant growth and yield. Plants have evolved…”
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Lyme Disease Pathogenesis by Coburn, Jenifer, Garcia, Brandon, Hu, Linden T, Jewett, Mollie W, Kraiczy, Peter, Norris, Steven J, Skare, Jon

“…Lyme disease are obligately parasitic, tick- transmitted, invasive, persistent bacterial pathogens that cause disease in humans and non-reservoir vertebrates…”
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Lyme Disease in Humans by Radolf, Justin D, Strle, Klemen, Lemieux, Jacob E, Strle, Franc

“…Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by genospecies of the sensu lato complex. The ailment, widespread…”
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Apple Replant Disease: Causes and Mitigation Strategies by Winkelmann, Traud, Smalla, Kornelia, Amelung, Wulf, Baab, Gerhard, Grunewaldt-Stöcker, Gisela, Kanfra, Xorla, Meyhöfer, Rainer, Reim, Stefanie, Schmitz, Michaela, Vetterlein, Doris, Wrede, Andreas, Zühlke, Sebastian, Grunewaldt, Jürgen, Weiß, Stefan, Schloter, Michael

“…After replanting apple (Malus domestica Borkh.) on the same site severe growth suppressions, and a decline in yield and fruit quality are observed in all apple…”
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How Plants Tolerate Salt Stress by Fu, Haiqi, Yang, Yongqing

“…Soil salinization inhibits plant growth and seriously restricts food security and agricultural development. Excessive salt can cause ionic stress, osmotic…”
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Ketogenic Diet in Cancer Prevention and Therapy: Molecular Targets and Therapeutic Opportunities by Talib, Wamidh H, Mahmod, Asma Ismail, Kamal, Ayah, Rashid, Hasan M, Alashqar, Aya M D, Khater, Samar, Jamal, Duaa, Waly, Mostafa

“…Although cancer is still one of the most significant global challenges facing public health, the world still lacks complementary approaches that would…”
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PGC-1: The Energetic Regulator in Cardiac Metabolism by Di, Wencheng, Lv, Jianjun, Jiang, Shuai, Lu, Chenxi, Yang, Zhi, Ma, Zhiqiang, Hu, Wei, Yang, Yang, Xu, Biao

“…The peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1s (PGC-1s) can induce the expression of several downstream genes that play pivotal roles…”
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A Critical Review: Recent Advancements in the Use of CRISPR/Cas9 Technology to Enhance Crops and Alleviate Global Food Crises by Rasheed, Adnan, Gill, Rafaqat Ali, Hassan, Muhammad Umair, Mahmood, Athar, Qari, Sameer, Zaman, Qamar U, Ilyas, Muhammad, Aamer, Muhammad, Batool, Maria, Li, Huijie, Wu, Ziming

“…Genome editing (GE) has revolutionized the biological sciences by creating a novel approach for manipulating the genomes of living organisms. Many tools have…”
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Synthesis, Molecular Docking, and Dynamic Simulation Targeting Main Protease (Mpro) of New, Thiazole Clubbed Pyridine Scaffolds as Potential COVID-19 Inhibitors by Alghamdi, Adel, Abouzied, Amr S, Alamri, Abdulwahab, Anwar, Sirajudheen, Ansari, Mukhtar, Khadra, Ibrahim, Zaki, Yasser H, Gomha, Sobhi M

“…Many biological activities of pyridine and thiazole derivatives have been reported, including antiviral activity and, more recently, as COVID-19 inhibitors…”
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Beneficial Effects of Red Wine Polyphenols on Human Health: Comprehensive Review by Buljeta, Ivana, Pichler, Anita, Šimunović, Josip, Kopjar, Mirela

“…Polyphenols are secondary plant metabolites synthesized during the development of the grape berry as a response to stress conditions. They are important…”
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Phage Therapy: The Pharmacology of Antibacterial Viruses by Danis-Wlodarczyk, Katarzyna, Dąbrowska, Krystyna, Abedon, Stephen T

“…Pharmacology can be differentiated into two key aspects, pharmacodynamics and pharmacokinetics. Pharmacodynamics describes a drug's impact on the body while…”
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Gender Differences in Insulin Resistance: New Knowledge and Perspectives by Ciarambino, Tiziana, Crispino, Pietro, Guarisco, Gloria, Giordano, Mauro

“…Insulin resistance is the main mechanism in a whole series of pathological conditions, which are not only of metabolic interest but also of a systemic type…”
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CRISPR/Cas9 Technique for Temperature, Drought, and Salinity Stress Responses by Li, Xiaohan, Xu, Siyan, Fuhrmann-Aoyagi, Martina Bianca, Yuan, Shaoze, Iwama, Takeru, Kobayashi, Misaki, Miura, Kenji

“…Global warming and climate change have severely affected plant growth and food production. Therefore, minimizing these effects is required for sustainable crop…”
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Porcine Parvovirus by Streck, André Felipe, Truyen, Uwe

“…Porcine parvovirus (PPV) is considered the main cause of reproductive disorders in pigs, which are summarized under the acronym SMEDI (stillbirth,…”
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Therapeutic Anti-Depressant Potential of Microbial GABA Produced by Lactobacillus rhamnosus Strains for GABAergic Signaling Restoration and Inhibition of Addiction-Induced HPA Axis Hyperactivity by Tette, Fernanda-Marie, Kwofie, Samuel K., Wilson, Michael D.

“…The role of the microbiota–gut–brain (MGB) axis in mood regulation and depression treatment has gained attention in recent years, as evidenced by the growing…”
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