Search Results - "Curran, Samuel C."

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation by Laberge, Remi-Martin, Sun, Yu, Orjalo, Arturo V., Patil, Christopher K., Freund, Adam, Zhou, Lili, Curran, Samuel C., Davalos, Albert R., Wilson-Edell, Kathleen A., Liu, Su, Limbad, Chandani, Demaria, Marco, Li, Patrick, Hubbard, Gene B., Ikeno, Yuji, Javors, Martin, Desprez, Pierre-Yves, Benz, Christopher C., Kapahi, Pankaj, Nelson, Peter S., Campisi, Judith

“…The TOR (target of rapamycin) kinase limits longevity by poorly understood mechanisms. Rapamycin suppresses the mammalian TORC1 complex, which regulates…”
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A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable by Leynaud-Kieffer, Laure M C, Curran, Samuel C, Kim, Irene, Magnuson, Jon K, Gladden, John M, Baker, Scott E, Simmons, Blake A

“…Aspergillus niger and other filamentous fungi are widely used in industry, but efficient genetic engineering of these hosts remains nascent. For example, while…”
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Structure and Function of BorB, the Type II Thioesterase from the Borrelidin Biosynthetic Gene Cluster by Curran, Samuel C, Pereira, Jose H, Baluyot, Marian-Joy, Lake, Julie, Puetz, Hendrik, Rosenburg, Daniel J, Adams, Paul, Keasling, Jay D

“…α/β hydrolases make up a large and diverse protein superfamily. In natural product biosynthesis, cis-acting thioesterase α/β hydrolases can terminate…”
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Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism by Thompson, Mitchell G, Blake-Hedges, Jacquelyn M, Cruz-Morales, Pablo, Barajas, Jesus F, Curran, Samuel C, Eiben, Christopher B, Harris, Nicholas C, Benites, Veronica T, Gin, Jennifer W, Sharpless, William A, Twigg, Frederick F, Skyrud, Will, Krishna, Rohith N, Pereira, Jose Henrique, Baidoo, Edward E K, Petzold, Christopher J, Adams, Paul D, Arkin, Adam P, Deutschbauer, Adam M, Keasling, Jay D

“…Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in remain unresolved. To establish…”
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Author Correction: MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation by Laberge, Remi-Martin, Sun, Yu, Orjalo, Arturo V., Patil, Christopher K., Freund, Adam, Zhou, Lili, Curran, Samuel C., Davalos, Albert R., Wilson-Edell, Kathleen A., Liu, Su, Limbad, Chandani, Demaria, Marco, Li, Patrick, Hubbard, Gene B., Ikeno, Yuji, Javors, Martin, Desprez, Pierre-Yves, Benz, Christopher C., Kapahi, Pankaj, Nelson, Peter S., Campisi, Judith

“…A Correction to this paper has been published: https://doi.org/10.1038/s41556-021-00655-4…”
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Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro by Curran, Samuel C, Hagen, Andrew, Poust, Sean, Chan, Leanne Jade G, Garabedian, Brett M, de Rond, Tristan, Baluyot, Marian-Joy, Vu, Jonathan T, Lau, Andrew K, Yuzawa, Satoshi, Petzold, Christopher J, Katz, Leonard, Keasling, Jay D

“…In the search for molecular machinery for custom biosynthesis of valuable compounds, the modular type I polyketide synthases (PKSs) offer great potential. In…”
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Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in italic toggle="yes">Pseudomonas putida /italic> Lysine Metabolism by Mitchell G. Thompson, Jacquelyn M. Blake-Hedges, Pablo Cruz-Morales, Jesus F. Barajas, Samuel C. Curran, Christopher B. Eiben, Nicholas C. Harris, Veronica T. Benites, Jennifer W. Gin, William A. Sharpless, Frederick F. Twigg, Will Skyrud, Rohith N. Krishna, Jose Henrique Pereira, Edward E. K. Baidoo, Christopher J. Petzold, Paul D. Adams, Adam P. Arkin, Adam M. Deutschbauer, Jay D. Keasling

“…ABSTRACT Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in Pseudomonas putida remain…”
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New Developments of Counting Tubes with Special Reference to the Study of Beta and Gamma Ray Spectra by Curran, Samuel C

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An Investigation of Some Wave-Properties of Beta-Rays by Curran, Samuel C

“…The following thesis cintains an account of researches performed by the author in the Research Laboratories of the Natural Philosophy Department at Glasgow…”
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