Search Results - "Curotto, Paula"

Therapeutic efficacy of boron neutron capture therapy mediated by boron-rich liposomes for oral cancer in the hamster cheek pouch model by Heber, Elisa M., Hawthorne, M. Frederick, Kueffer, Peter J., Garabalino, Marcela A., Thorp, Silvia I., Pozzi, Emiliano C. C., Hughes, Andrea Monti, Maitz, Charles A., Jalisatgi, Satish S., Nigg, David W., Curotto, Paula, Trivillin, Verónica A., Schwint, Amanda E.

“…The application of boron neutron capture therapy (BNCT) mediated by liposomes containing ¹⁰B-enriched polyhedral borane and carborane derivatives for the…”
Get full text

Evaluation of local, regional and abscopal effects of Boron Neutron Capture Therapy (BNCT) combined with immunotherapy in an ectopic colon cancer model by Trivillin, Verónica A, Langle, Yanina V, Palmieri, Mónica A, Pozzi, Emiliano C C, Thorp, Silvia I, Benitez Frydryk, Debora N, Garabalino, Marcela A, Monti Hughes, Andrea, Curotto, Paula M, Colombo, Lucas L, Santa Cruz, Iara S, Ramos, Paula S, Itoiz, María E, Argüelles, Claudia, Eiján, Ana M, Schwint, Amanda E

“…The aim of the present study was to evaluate the local and regional therapeutic efficacy and abscopal effect of BNCT mediated by boronophenyl-alanine, combined…”
Get full text

Translational boron neutron capture therapy (BNCT) studies for the treatment of tumors in lung by Trivillin, Verónica Andrea, Serrano, Ayelén, Garabalino, Marcela A., Colombo, Lucas Luis, Pozzi, Emiliano César, Hughes, Andrea Monti, Curotto, Paula M., Thorp, Silvia Inés, Farías, Ruben O., González, Sara J., Bortolussi, Silva, Altieri, Saverio, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Schwint, Amanda E.

“…Purpose: Boron neutron capture therapy (BNCT) combines selective accumulation of 10 B carriers in tumor tissue with subsequent neutron irradiation. BNCT has…”
Get full text

Neutron autoradiography to study the microdistribution of boron in the lung by Espain, María Sol, Dattoli Viegas, Ana Mailén, Trivillin, Verónica Andrea, Saint Martin, Gisela, Thorp, Silvia Inés, Curotto, Paula, Pozzi, Emiliano César Cayetano, González, Sara Josefina, Portu, Agustina Mariana

“…In Argentina, a multi-institutional project has been established to assess the feasibility of applying BNCT ex-situ to the treatment of patients with multiple…”
Get full text

Cobaltabis(Dicarbollide) [ o -COSAN] - for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model by Palmieri, Mónica A, Monti Hughes, Andrea, Trivillin, Verónica A, Garabalino, Marcela A, Ramos, Paula S, Thorp, Silvia I, Curotto, Paula, Pozzi, Emiliano C C, Nuez Martínez, Miquel, Teixidor, Francesc, Viñas, Clara, Schwint, Amanda E

“…Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
Get full text

Closo -Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy by Couto, Marcos, Alamón, Catalina, García, María Fernanda, Kovacs, Mariángeles, Trias, Emiliano, Nievas, Susana, Pozzi, Emiliano, Curotto, Paula, Thorp, Silvia, Dagrosa, María Alejandra, Teixidor, Francesc, Viñas, Clara, Cerecetto, Hugo

“…One of the driving forces of carcinogenesis in humans is the aberrant activation of receptors; consequently, one of the most promising mechanisms for cancer…”
Get full text

Enhanced Resolution of Neutron Autoradiography with UV-C Sensitization to Study Boron Microdistribution in Animal Models by Portu, Agustina Mariana, Espain, María Sol, Thorp, Silvia Inés, Trivillin, Verónica Andrea, Curotto, Paula, Monti Hughes, Andrea, Pozzi, Emiliano César Cayetano, Garabalino, Marcela Alejandra, Palmieri, Mónica Alejandra, Granell, Pablo Nicolás, Golmar, Federico, Schwint, Amanda Elena, Saint Martin, Gisela

“…The assessment of boron microdistribution is essential to evaluate the suitability of boron neutron capture therapy (BNCT) in different biological models. In…”
Get full text

Neutron autoradiography to study boron compound microdistribution in an oral cancer model by Portu, Agustina, Molinari, Ana Julia, Thorp, Silvia Inés, Pozzi, Emiliano César Cayetano, Curotto, Paula, Schwint, Amanda Elena, Saint Martin, Gisela

“…Abstract Purpose: We previously reported the therapeutic efficacy of Sequential Boron Neutron Capture Therapy (Seq-BNCT), i.e., BPA (boronophenylalanine) -…”
Get full text

Enhancement in the Therapeutic Efficacy of In Vivo BNCT Mediated by GB-10 with Electroporation in a Model of Oral Cancer by Olaiz, Nahuel, Monti Hughes, Andrea, Pozzi, Emiliano C C, Thorp, Silvia, Curotto, Paula, Trivillin, Verónica A, Ramos, Paula S, Palmieri, Mónica A, Marshall, Guillermo, Schwint, Amanda E, Garabalino, Marcela A

“…Boron neutron capture therapy (BNCT) combines preferential tumor uptake of B compounds and neutron irradiation. Electroporation induces an increase in the…”
Get full text

Therapeutic Efficacy, Radiotoxicity and Abscopal Effect of BNCT at the RA-3 Nuclear Reactor Employing Oligo-Fucoidan and Glutamine as Adjuvants in an Ectopic Colon Cancer Model in Rats by Frydryk Benitez, Debora N, Palmieri, Mónica A, Langle, Yanina V, Monti Hughes, Andrea, Pozzi, Emiliano C C, Thorp, Silvia I, Garabalino, Marcela A, Curotto, Paula, Ramos, Paula S, Paparella, María L, Polti, Lucas, Eiján, Ana, Schwint, Amanda E, Trivillin, Verónica A

“…Boron neutron capture therapy (BNCT) is based on the preferential uptake of B compounds by tumors, followed by neutron irradiation. The aim of this study was…”
Get full text

Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized Closo-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and In Vivo BNCT in the Hamster Cheek Pouch Oral Cancer Model by Monti Hughes, Andrea, Goldfinger, Jessica A., Palmieri, Mónica A., Ramos, Paula, Santa Cruz, Iara S., De Leo, Luciana, Garabalino, Marcela A., Thorp, Silvia I., Curotto, Paula, Pozzi, Emiliano C. C., Kawai, Kazuki, Sato, Shinichi, Itoiz, María E., Trivillin, Verónica A., Guidobono, Juan S., Nakamura, Hiroyuki, Schwint, Amanda E.

“…Background: BNCT (Boron Neutron Capture Therapy) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
Get full text

Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer by Trivillin, Verónica A., Pozzi, Emiliano C. C., Colombo, Lucas L., Thorp, Silvia I., Garabalino, Marcela A., Monti Hughes, Andrea, González, Sara J., Farías, Rubén O., Curotto, Paula, Santa Cruz, Gustavo A., Carando, Daniel G., Schwint, Amanda E.

“…The aim of the present study was to evaluate, for the first time, the abscopal effect of boron neutron capture therapy (BNCT). Twenty-six BDIX rats were…”
Get full text

Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: dose–response at five-week follow-up based on retrospective dose assessment in individual rats by Pozzi, Emiliano C. C., Trivillin, Verónica A., Colombo, Lucas L., Monti Hughes, Andrea, Thorp, Silvia I., Cardoso, Jorge E., Garabalino, Marcela A., Molinari, Ana J., Heber, Elisa M., Curotto, Paula, Miller, Marcelo, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. Employing an experimental model of liver metastases in rats, we…”
Get full text

Cobaltabis(Dicarbollide) o-COSAN- for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model by Palmieri, Mónica A, Monti Hughes, Andrea, Trivillin, Verónica A, Garabalino, Marcela A, Ramos, Paula S, Thorp, Silvia I, Curotto, Paula, Pozzi, Emiliano C C, Nuez Martínez, Miquel, Teixidor, Francesc, Viñas, Clara, Schwint, Amanda E

“…Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
Get full text

Optimization of the classical oral cancerization protocol in hamster to study oral cancer therapy by Santa Cruz, Iara S., Garabalino, Marcela A., Trivillin, Verónica A., Itoiz, María E., Pozzi, Emiliano C. C., Thorp, Silvia, Curotto, Paula, Guidobono, Juan S., Heber, Elisa M., Nigg, David W., Schwint, Amanda E., Monti Hughes, Andrea

“…Objective(s) The hamster carcinogenesis model recapitulates oral oncogenesis. Dimethylbenz[a]anthracene (DMBA) cancerization induces early severe mucositis,…”
Get full text

Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model by Garabalino, Marcela A., Olaiz, Nahuel, Portu, Agustina, Saint Martin, Gisela, Thorp, Silvia I., Pozzi, Emiliano C. C., Curotto, Paula, Itoiz, María E., Monti Hughes, Andrea, Colombo, Lucas L., Nigg, David W., Trivillin, Verónica A., Marshall, Guillermo, Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) is a promising cancer binary therapy modality that utilizes the nuclear capture reaction of thermal neutrons by boron-10…”
Get full text

Extending neutron autoradiography technique for boron concentration measurements in hard tissues by Provenzano, Lucas, Olivera, María Silvina, Saint Martin, Gisela, Rodríguez, Luis Miguel, Fregenal, Daniel, Thorp, Silvia I., Pozzi, Emiliano C.C., Curotto, Paula, Postuma, Ian, Altieri, Saverio, González, Sara J., Bortolussi, Silva, Portu, Agustina

“…The neutron autoradiography technique using polycarbonate nuclear track detectors (NTD) has been extended to quantify the boron concentration in hard tissues,…”
Get full text

Different oral cancer scenarios to personalize targeted therapy: Boron Neutron Capture Therapy translational studies by Hughes, Andrea Monti, Goldfinger, Jessica A, Santa Cruz, Iara S, Pozzi, Emiliano CC, Thorp, Silvia, Curotto, Paula, Garabalino, Marcela A, Itoiz, María E, Palmieri, Mónica A, Ramos, Paula, Heber, Elisa M, Aromando, Romina F, Nigg, David W, Koivunoro, Hanna, Trivillin, Verónica A, Schwint, Amanda E

“…Boron neutron capture therapy (BNCT) is a targeted therapy, which consists of preferential accumulation of boron carriers in tumor followed by neutron…”
Get full text

Simultaneous Observation of Cells and Nuclear Tracks from the Boron Neutron Capture Reaction by UV-C Sensitization of Polycarbonate by Portu, Agustina, Rossini, Andrés Eugenio, Thorp, Silvia Inés, Curotto, Paula, Pozzi, Emiliano César Cayetano, Granell, Pablo, Golmar, Federico, Cabrini, Rómulo Luis, Martin, Gisela Saint

“…The distribution of boron in tissue samples coming from boron neutron capture therapy protocols can be determined through the analysis of its autoradiography…”
Get more information

Experimental set up for the irradiation of biological samples and nuclear track detectors with UV C by Portu, Agustina Mariana, Rossini, Andrés Eugenio, Gadan, Mario Alberto, Bernaola, Omar Alberto, Thorp, Silvia Inés, Curotto, Paula, Pozzi, Emiliano César Cayetano, Cabrini, Rómulo Luis, Martin, Gisela Saint

“…Abstract Aim In this work we present a methodology to produce an “imprint” of cells cultivated on a polycarbonate detector by exposure of the detector to UV C…”
Get full text