Search Results - "Curotto, A"

IgG1 memory B cells keep the memory of IgE responses by He, Jin-Shu, Subramaniam, Sharrada, Narang, Vipin, Srinivasan, Kandhadayar, Saunders, Sean P., Carbajo, Daniel, Wen-Shan, Tsao, Hidayah Hamadee, Nur, Lum, Josephine, Lee, Andrea, Chen, Jinmiao, Poidinger, Michael, Zolezzi, Francesca, Lafaille, Juan J., Curotto de Lafaille, Maria A.

“…The unique differentiation of IgE cells suggests unconventional mechanisms of IgE memory. IgE germinal centre cells are transient, most IgE cells are plasma…”
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Oral tolerance to dietary antigens and Foxp3 + regulatory T cells by Miranda-Waldetario, Mariana C G, Curotto de Lafaille, Maria A

“…Immune tolerance to foods develops in the intestine upon food ingestion and is essential to prevent IgE-mediated food allergy and gut inflammation. In…”
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Sequential class switching is required for the generation of high affinity IgE antibodies by Xiong, Huizhong, Dolpady, Jayashree, Wabl, Matthias, Curotto de Lafaille, Maria A, Lafaille, Juan J

“…IgE antibodies with high affinity for their antigens can be stably cross-linked at low concentrations by trace amounts of antigen, whereas IgE antibodies with…”
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CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy by Ota, Miyo, Hoehn, Kenneth B, Fernandes-Braga, Weslley, Ota, Takayuki, Aranda, Carlos J, Friedman, Sara, Miranda-Waldetario, Mariana G C, Redes, Jamie, Suprun, Maria, Grishina, Galina, Sampson, Hugh A, Malbari, Alefiyah, Kleinstein, Steven H, Sicherer, Scott H, Curotto de Lafaille, Maria A

“…Food allergy is caused by allergen-specific immunoglobulin E (IgE) antibodies, but little is known about the B cell memory of persistent IgE responses. Here,…”
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IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases by Aranda, Carlos J., Gonzalez‐Kozlova, Edgar, Saunders, Sean P., Fernandes‐Braga, Weslley, Ota, Miyo, Narayanan, Sriram, He, Jin‐Shu, Del Duca, Ester, Swaroop, Bose, Gnjatic, Sacha, Shattner, Gail, Reibman, Joan, Soter, Nicholas A., Guttman‐Yassky, Emma, Curotto de Lafaille, Maria A.

“…Background Atopic diseases are characterized by IgE antibody responses that are dependent on cognate CD4 T cell help and T cell‐produced IL‐4 and IL‐13…”
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The Secret Life of IgE-Producing Cells by Aranda, Carlos J., Curotto de Lafaille, Maria A.

“…IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals…”
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Natural and Adaptive Foxp3 + Regulatory T Cells: More of the Same or a Division of Labor? by Curotto de Lafaille, Maria A., Lafaille, Juan J.

“…Adaptive Foxp3 +CD4 + regulatory T (iTreg) cells develop outside the thymus under subimmunogenic antigen presentation, during chronic inflammation, and during…”
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Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells by Lafaille, Juan J, Curotto de Lafaille, Maria A, Shen, Shiqian, Lino, Andreia C, Ding, Yi

“…β-catenin is a central molecule in the Wnt pathway. Expression of a stable form of β-catenin on CD4 + CD25 + regulatory T (T reg ) cells resulted in a marked…”
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B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice by Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, Curotto de Lafaille, Maria A, Wakeland, Edward K, Fairhurst, Anna-Marie

“…Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease characterized by the production of antinuclear autoantibodies. Antinuclear…”
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Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells by Weiss, Jonathan M, Bilate, Angelina M, Gobert, Michael, Ding, Yi, Curotto de Lafaille, Maria A, Parkhurst, Christopher N, Xiong, Huizhong, Dolpady, Jayashree, Frey, Alan B, Ruocco, Maria Grazia, Yang, Yi, Floess, Stefan, Huehn, Jochen, Oh, Soyoung, Li, Ming O, Niec, Rachel E, Rudensky, Alexander Y, Dustin, Michael L, Littman, Dan R, Lafaille, Juan J

“…Foxp3 activity is essential for the normal function of the immune system. Two types of regulatory T (T reg) cells express Foxp3, thymus-generated natural T reg…”
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Adaptive Foxp3 + Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation by Curotto de Lafaille, Maria A., Kutchukhidze, Nino, Shen, Shiqian, Ding, Yi, Yee, Herman, Lafaille, Juan J.

“…Adaptive Foxp3 + regulatory T (Treg) cells develop during induction of mucosal tolerance and after immunization. Large numbers of Foxp3 + T cells have been…”
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Making good of a tricky start: How IgE and mast cells manage a protective sway in food allergy by Miranda-Waldetario, Mariana C.G., Curotto de Lafaille, Maria A.

“…The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the…”
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Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation by Bleck, Bertram, Tse, Doris B, Jaspers, Ilona, Curotto de Lafaille, Maria A, Reibman, Joan

“…Increased exposure to air pollutants such as diesel exhaust particles (DEP) has been proposed as one mechanism to explain the rise in allergic disorders…”
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Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore by Thalayasingam, M., Gerez, I. F. A., Yap, G. C., Llanora, G. V., Chia, I. P., Chua, L., Lee, C. J. A. O., Ta, L. D. H., Cheng, Y. K., Thong, B. Y. H., Tang, C. Y., Van Bever, H. P. S., Shek, L. P., Curotto de Lafaille, M. A., Lee, B. W.

“…Summary Background Shellfish allergy in Singapore is highly prevalent, and shrimp allergy is the most common. Objective This study aims to evaluate the…”
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Tumor-draining lymph nodes demonstrate a suppressive immunophenotype in patients with non-small cell lung cancer assessed by endobronchial ultrasound-guided transbronchial needle aspiration: A pilot study by Murthy, Vivek, Katzman, Daniel P., Tsay, Jun-Chieh J., Bessich, Jamie L., Michaud, Gaetane C., Rafeq, Samaan, Minehart, Janna, Mangalick, Keshav, de Lafaille, M. A. Curotto, Goparaju, Chandra, Pass, Harvey, Sterman, Daniel H.

“…•TDLN in patients with NSCLC had a different immunophenotype from paired NDLN.•TDLN had significantly more Tregs and fewer effector CD4 + T cells.•Regional…”
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The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response by He, Jin-Shu, Meyer-Hermann, Michael, Xiangying, Deng, Zuan, Lim Yok, Jones, Leigh Ann, Ramakrishna, Lakshmi, de Vries, Victor C, Dolpady, Jayashree, Aina, Hoi, Joseph, Sabrina, Narayanan, Sriram, Subramaniam, Sharrada, Puthia, Manoj, Wong, Glenn, Xiong, Huizhong, Poidinger, Michael, Urban, Joseph F, Lafaille, Juan J, Curotto de Lafaille, Maria A

“…The mechanisms involved in the maintenance of memory IgE responses are poorly understood, and the role played by germinal center (GC) IgE(+) cells in memory…”
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Non-classical B Cell Memory of Allergic IgE Responses by Saunders, Sean P, Ma, Erica G M, Aranda, Carlos J, Curotto de Lafaille, Maria A

“…The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells…”
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Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin by Bleck, Bertram, Tse, Doris B., Curotto de Lafaille, Maria A., Zhang, Feijie, Reibman, Joan

“…Human exposure to air pollutants, including ambient particulate matter, has been proposed as a mechanism for the rise in allergic disorders. Diesel exhaust…”
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Biology of IgE production: IgE cell differentiation and the memory of IgE responses by He, Jin-Shu, Narayanan, Sriram, Subramaniam, Sharrada, Ho, Wen Qi, Lafaille, Juan J, Curotto de Lafaille, Maria A

“…The generation of long-lived plasma cells and memory B cells producing high-affinity antibodies depends on the maturation of B cell responses in germinal…”
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Publisher Correction: IgG1 memory B cells keep the memory of IgE responses by He, Jin-Shu, Subramaniam, Sharrada, Narang, Vipin, Srinivasan, Kandhadayar, Saunders, Sean P., Carbajo, Daniel, Wen-Shan, Tsao, Hidayah Hamadee, Nur, Lum, Josephine, Lee, Andrea, Chen, Jinmiao, Poidinger, Michael, Zolezzi, Francesca, Lafaille, Juan J., Curotto de Lafaille, Maria A.

“…The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost…”
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