Search Results - "Curinha, Ana"
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MCL1 alternative polyadenylation is essential for cell survival and mitochondria morphology
Published in Cellular and molecular life sciences : CMLS (01-03-2022)“…Alternative polyadenylation in the 3′ UTR (3′ UTR-APA) is a mode of gene expression regulation, fundamental for mRNA stability, translation and localization…”
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Journal Article -
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PLK4 self-phosphorylation drives the selection of a single site for procentriole assembly
Published in The Journal of cell biology (04-12-2023)“…Polo-like kinase 4 (PLK4) is a key regulator of centriole biogenesis, but how PLK4 selects a single site for procentriole assembly remains unclear. Using…”
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Journal Article -
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Correction: PLK4 self-phosphorylation drives the selection of a single site for procentriole assembly
Published in The Journal of cell biology (2024)Get full text
Journal Article -
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Implications of polyadenylation in health and disease
Published in Nucleus (Austin, Tex.) (02-11-2014)“…Polyadenylation is the RNA processing step that completes the maturation of nearly all eukaryotic mRNAs. It is a two-step nuclear process that involves an…”
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Journal Article -
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PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis
Published in EMBO reports (03-12-2020)“…Polyploidization frequently precedes tumorigenesis but also occurs during normal development in several tissues. Hepatocyte ploidy is controlled by the…”
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Journal Article -
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Regulation of MCL1 Alternative Polyadenylationderived mRNA Isoforms by Micrornas in Human T Cells
Published 01-01-2016“…A poliadenilação é um passo de processamento fundamental da maturação do mRNA, essencial para o seu transporte, estabilidade e tradução. Análises…”
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Dissertation