Search Results - "Curci, J A"

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms by Curci, J A, Liao, S, Huffman, M D, Shapiro, S D, Thompson, R W

“…Elastolytic matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of abdominal aortic aneurysms (AAA), a disorder characterized by chronic…”
Get full text

Pharmacologic suppression of experimental abdominal aortic aneurysms: A comparison of doxycycline and four chemically modified tetracyclines by Curci, John A., Petrinec, Drazen, Liao, Shixiong, Golub, Lorne M., Thompson, Robert W.

“…Background: Matrix metalloproteinases (MMPs) likely contribute to the degradation of medial elastin in abdominal aortic aneurysms (AAAs), and tetracycline…”
Get full text

Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908) by Moore, Gail, Liao, Shixiong, Curci, John A., Starcher, Barry C., Martin, Robert L., Hendricks, Robert T., Chen, Jeffrey J., Thompson, Robert W.

“…Background: Abdominal aortic aneurysms (AAAs) are associated with chronic inflammation, disruption of medial elastin, and increased local production of…”
Get full text

Accelerated Replicative Senescence of Medial Smooth Muscle Cells Derived from Abdominal Aortic Aneurysms Compared to the Adjacent Inferior Mesenteric Artery by Liao, Shixiong, Curci, John A., Kelley, Brian J., Sicard, Gregorio A., Thompson, Robert W.

“…Background. Abdominal aortic aneurysms (AAAs) are associated with aging and atherosclerosis. AAAs arise through a degenerative process characterized in part by…”
Get full text

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms by Pyo, R, Lee, J K, Shipley, J M, Curci, J A, Mao, D, Ziporin, S J, Ennis, T L, Shapiro, S D, Senior, R M, Thompson, R W

“…Abdominal aortic aneurysms represent a life-threatening condition characterized by chronic inflammation, destructive remodeling of the extracellular matrix,…”
Get full text

Variable induction of experimental abdominal aortic aneurysms with different preparations of porcine pancreatic elastase by Curci, John A., Thompson, Robert W.

Get full text

Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors by Liao, Shixiong, Miralles, Manuel, Kelley, Brian J., Curci, John A., Borhani, Martin, Thompson, Robert W.

“…Purpose: Pathologic remodeling of the extracellular matrix is a critical mechanism in the development and progression of abdominal aortic aneurysms (AAAs)…”
Get full text

Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms by Curci, John A, Mao, Dongli, Bohner, Diane G, Allen, Brent T, Rubin, Brian G, Reilly, Jeffrey M, Sicard, Gregorio A, Thompson, Robert W

“…Purpose: Matrix metalloproteinases (MMPs) are considered to play a central role in the pathogenesis of abdominal aortic aneurysms (AAAs). Doxycycline (Dox) has…”
Get full text

Elevated plasma levels of matrix metalloproteinase-9 in patients with abdominal aortic aneurysms: a circulating marker of degenerative aneurysm disease by Hovsepian, D M, Ziporin, S J, Sakurai, M K, Lee, J K, Curci, J A, Thompson, R W

“…Matrix metalloproteinase-9 (MMP-9) is abundantly expressed in abdominal aortic aneurysms (AAAs), where it plays a pivotal role in connective tissue…”
Get more information

Expression of matrix metalloproteinases and TIMPs in human abdominal aortic aneurysms by Mao, D, VanVickle, S J, Curci, J A, Thompson, R W

Get more information

Functional importance of connective tissue repair during the development of experimental abdominal aortic aneurysms by Huffman, Mark D., Curci, John A., Moore, Gail, Kerns, D.Brent, Starcher, Barry C., Thompson, Robert W.

“…Background. Abdominal aortic aneurysms (AAAs) involve an unfavorable balance between the destruction and the repair of connective tissue proteins. The purpose…”
Get full text

Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms by Thompson, R W, Liao, S, Curci, J A

“…Apoptosis is a naturally occurring mechanism of cell death that plays an important role in both normal and pathological remodeling of the vessel wall…”
Get more information

Therapeutic potential of tetracycline derivatives to suppress the growth of abdominal aortic aneurysms by Thompson, R W, Liao, S, Curci, J A

“…Abdominal aortic aneurysms (AAA) represent a potentially lethal disorder associated with aging and atherosclerosis. Although current management of AAA is…”
Get more information

Mercury poisoning associated with high‐dose hepatitis‐B immune globulin administration after liver transplantation for chronic hepatitis B by Lowell, Jeffry A., Burgess, Sandy, Shenoy, Surendra, Curci, John A., Peters, Marion, Howard, Todd K.

Get full text

Source of elastin-degrading enzymes in mycotic aortic aneurysms: bacteria or host inflammatory response? by Buckmaster, M J, Curci, J A, Murray, P R, Liao, S, Allen, B T, Sicard, G A, Thompson, R W

“…Elastolytic matrix metalloproteinases play a central role in the development of chronic atherosclerotic aortic aneurysms, but mycotic aortic aneurysms are a…”
Get more information

Adaptive cellular immunity in aortic aneurysms: cause, consequence, or context? by Curci, John A., Thompson, Robert W.

“…Abdominal aortic aneurysms are common and life threatening. Although CD4 + T cells are abundant in aneurysm tissue, their role in disease progression remains…”
Get full text

We need more vascular research by Dardik, Alan, Curci, John A., Tang, Gale L., Hedin, Ulf, Sadaghianloo, Nirvana, Roy, Trisha L., Dalman, Ronald L.

Get full text

A histopathological classification scheme for abdominal aortic aneurysm disease by Bruijn, Laura E., van Stroe Gómez, Charid G., Curci, John A., Golledge, Jonathan, Hamming, Jaap F., Jones, Greg T., Lee, Regent, Matic, Ljubica, van Rhijn, Connie, Vriens, Patrick W., Wågsäter, Dick, Xu, Baohui, Yamanouchi, Dai, Lindeman, Jan H.

“…Two consensus histopathological classifications for thoracic aortic aneurysms (TAAs) and inflammatory aortic diseases have been issued to facilitate clinical…”
Get full text

Retrograde visceral vessel revascularization followed by endovascular aneurysm exclusion as an alternative to open surgical repair of thoracoabdominal aortic aneurysm by FLYE, M. Wayne, CHOI, Eric T, SANCHEZ, Luis A, CURCI, John A, THOMPSON, Robert W, RUBIN, Brian G, GERAGHTY, Patrick J, SICARD, Gregorio A

“…Staged visceral artery revascularization with occlusion of the proximal lumen enables endovascular exclusion of the entire thoracoabdominal aneurysm from a…”
Get full text

Overt ischemic colitis after endovascular repair of aortoiliac aneurysms by Geraghty, Patrick J., Sanchez, Luis A., Rubin, Brian G., Choi, Eric T., Flye, M.Wayne, Curci, John A., Thompson, Robert W., Sicard, Gregorio A.

“…Controversy exists as to the cause of ischemic colitis complicating endovascular aneurysm repair. Occlusion of the hypogastric arteries (HAs) during…”
Get full text