Search Results - "Curak, Jasna"
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1
Accurate Models for P‑gp Drug Recognition Induced from a Cancer Cell Line Cytotoxicity Screen
Published in Journal of medicinal chemistry (25-07-2013)“…P-glycoprotein (P-gp, MDR1) is a promiscuous drug efflux pump of substantial pharmacological importance. Taking advantage of large-scale cytotoxicity screening…”
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2
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Published in Nature communications (24-01-2020)“…Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their…”
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3
Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
Published in Molecular systems biology (21-06-2011)“…Resistance to widely used fungistatic drugs, particularly to the ergosterol biosynthesis inhibitor fluconazole, threatens millions of immunocompromised…”
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4
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation
Published in Cell reports (Cambridge) (25-10-2012)“…The pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types…”
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5
The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing
Published in International orthopaedics (01-03-2014)“…Purpose The purpose of this study was to revise the clinical use of commercial BMP2 (Infuse) and BMP7 (Osigraft) based bone devices and explore the mechanism…”
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6
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6
Published in Science signaling (22-12-2009)“…Binding of epidermal growth factor (EGF) to its receptor leads to receptor dimerization, assembly of protein complexes, and activation of signaling networks…”
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7
Yeast as a tool to study bacterial effectors
Published in Current opinion in microbiology (01-02-2009)“…Many bacterial pathogens rely on effector proteins to disrupt conserved eukaryotic processes. Despite their fundamental biological importance, it has been…”
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Split-ubiquitin based membrane yeast two-hybrid (MYTH) system: a powerful tool for identifying protein-protein interactions
Published in Journal of visualized experiments (01-02-2010)“…The fundamental biological and clinical importance of integral membrane proteins prompted the development of a yeast-based system for the high-throughput…”
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Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen
Published in PLoS genetics (01-02-2008)“…Pseudomonas aeruginosa is an opportunistic human pathogen that is a key factor in the mortality of cystic fibrosis patients, and infection represents an…”
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10
Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast
Published in Nature protocols (01-07-2010)“…The biological function of proteins may be predicted by identification of their interacting partners, and one of the major goals of the postgenomic era is the…”
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11
Investigating the ErbB protein interactome
Published 01-01-2010“…The erythroblastoma (ErbB) receptor family consists of four members that are implicated in many human cancers. To gain insight into their biological function,…”
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Dissertation -
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Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS G13D
Published in Nature communications (24-01-2020)“…Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their…”
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Journal Article -
13
Split-Ubiquitin Based Membrane Yeast Two-Hybrid (MYTH) System: A Powerful Tool For Identifying Protein-Protein Interactions
Published in Journal of visualized experiments (01-02-2010)Get full text
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14
Correction: Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen
Published in PLoS genetics (02-04-2008)Get full text
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Correction: Identification of Small Molecule Inhibitors of Exoenzyme S Using a Yeast Phenotypic Screen
Published in PLoS genetics (01-04-2008)Get full text
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16
Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen: e1000005
Published in PLoS genetics (01-02-2008)“…Pseudomonas aeruginosa is an opportunistic human pathogen that is a key factor in the mortality of cystic fibrosis patients, and infection represents an…”
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Journal Article