Search Results - "Curak, Jasna"

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    Accurate Models for P‑gp Drug Recognition Induced from a Cancer Cell Line Cytotoxicity Screen by Levatić, Jurica, Ćurak, Jasna, Kralj, Marijeta, Šmuc, Tomislav, Osmak, Maja, Supek, Fran

    Published in Journal of medicinal chemistry (25-07-2013)
    “…P-glycoprotein (P-gp, MDR1) is a promiscuous drug efflux pump of substantial pharmacological importance. Taking advantage of large-scale cytotoxicity screening…”
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    Journal Article
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    Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole by Spitzer, Michaela, Griffiths, Emma, Blakely, Kim M, Wildenhain, Jan, Ejim, Linda, Rossi, Laura, De Pascale, Gianfranco, Curak, Jasna, Brown, Eric, Tyers, Mike, Wright, Gerard D

    Published in Molecular systems biology (21-06-2011)
    “…Resistance to widely used fungistatic drugs, particularly to the ergosterol biosynthesis inhibitor fluconazole, threatens millions of immunocompromised…”
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    Journal Article
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    Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation by Mak, Anthony B., Nixon, Allison M.L., Kittanakom, Saranya, Stewart, Jocelyn M., Chen, Ginny I., Curak, Jasna, Gingras, Anne-Claude, Mazitschek, Ralph, Neel, Benjamin G., Stagljar, Igor, Moffat, Jason

    Published in Cell reports (Cambridge) (25-10-2012)
    “…The pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types…”
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    Journal Article
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    Yeast as a tool to study bacterial effectors by Curak, Jasna, Rohde, John, Stagljar, Igor

    Published in Current opinion in microbiology (01-02-2009)
    “…Many bacterial pathogens rely on effector proteins to disrupt conserved eukaryotic processes. Despite their fundamental biological importance, it has been…”
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    Journal Article
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    Split-ubiquitin based membrane yeast two-hybrid (MYTH) system: a powerful tool for identifying protein-protein interactions by Snider, Jamie, Kittanakom, Saranya, Curak, Jasna, Stagljar, Igor

    Published in Journal of visualized experiments (01-02-2010)
    “…The fundamental biological and clinical importance of integral membrane proteins prompted the development of a yeast-based system for the high-throughput…”
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    Journal Article
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    Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast by Stagljar, Igor, Snider, Jamie, Kittanakom, Saranya, Damjanovic, Dunja, Curak, Jasna, Wong, Victoria

    Published in Nature protocols (01-07-2010)
    “…The biological function of proteins may be predicted by identification of their interacting partners, and one of the major goals of the postgenomic era is the…”
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    Journal Article
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    Investigating the ErbB protein interactome by Curak, Jasna

    Published 01-01-2010
    “…The erythroblastoma (ErbB) receptor family consists of four members that are implicated in many human cancers. To gain insight into their biological function,…”
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    Dissertation
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