Search Results - "Cupello, A"

Modulation of native GABA(A) receptor activity by triazolo 1,5-benzodiazepines by Nikas, P, Gatta, E, Cupello, A, Di Braccio, M, Grossi, G, Pellistri, F, Robello, M

“…In previous work our group described the synthesis and the activity on rat cerebellum granule cell GABAA receptors of new 1,5-benzodiazepine compounds. Here we…”
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Modulation of native GABAA receptor activity by triazolo 1,5-benzodiazepines by Nikas, P, Gatta, E, Cupello, A, Di Braccio, M, Grossi, G, Pellistri, F, Robello, M

“…Highlights • Synthesis of new 1,5-benzodiazepine derivatives. • Use of patch-clamp technique on rat cerebellar granule cells in culture. • 1,5-Benzodiazepine…”
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Neuronal transmembrane chloride electrochemical gradient: a key player in GABA A receptor activation physiological effect by Cupello, A

“…It has long been accepted that GABA is the main inhibitory neurotransmitter in the mammalian brain, acting via GABA(A) or GABA(B) receptors. However, new…”
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GABAA receptors of cerebellar granule cells in culture: explanation of overall insensitivity to ethanol by Gatta, E, Cupello, A, Pellistri, F, Robello, M

“…Abstract GABA-activated chloride currents were studied in cerebellar granule cells put in culture from neonatal rats. As previously described, 10 μM GABA…”
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GABA(A) receptors of cerebellar granule cells in culture: explanation of overall insensitivity to ethanol by Gatta, E, Cupello, A, Pellistri, F, Robello, M

“…GABA-activated chloride currents were studied in cerebellar granule cells put in culture from neonatal rats. As previously described, 10 microM GABA perfusion…”
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New 1,5-benzodiazepine compounds: activity at native GABA A receptors by Gatta, E., Cupello, A., Di Braccio, M., Grossi, G., Ferruzzi, R., Roma, G., Robello, M.

“…Various new 1,5-benzodiazepine compounds were synthesized and tested for their biological activity in terms of effects on GABA A receptors of rat cerebellar…”
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New 1,5-benzodiazepine compounds: activity at native GABAA receptors by Gatta, E, Cupello, A, Di Braccio, M, Grossi, G, Ferruzzi, R, Roma, G, Robello, M

“…Abstract Various new 1,5-benzodiazepine compounds were synthesized and tested for their biological activity in terms of effects on GABAA receptors of rat…”
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Successful treatment of epilepsy with serotonin reuptake inhibitors: proposed mechanism by Albano, C, Cupello, A, Mainardi, P, Scarrone, S, Favale, E

“…The widely used antidepressants Specific Serotonin Reuptake Inhibitors (SSRI) have been tried with success as anticonvulsants in cases of nonsymptomatic…”
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Only high concentrations of ethanol affect GABAA receptors of rat cerebellum granule cells in culture by CASAGRANDE, S, CUPELLO, A, PELLISTRI, F, ROBELLO, M

“…In the experiments described in the present report, we evaluated the effects of ethanol on the activity of GABAA receptors of cerebellar granule cells in…”
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The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds by Lunardi, G., Parodi, A., Perasso, L., Pohvozcheva, A.V., Scarrone, S., Adriano, E., Florio, T., Gandolfo, C., Cupello, A., Burov, S.V., Balestrino, M.

“…Hereditary creatine transporter deficiency causes brain damage, despite the brain having the enzymes to synthesize creatine. Such damage occurring despite an…”
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Activation of cerebellar granule cells GABA A receptors by guanidinoacetate by Cupello, A., Balestrino, M., Gatta, E., Pellistri, F., Siano, S., Robello, M.

“…The extracellular concentration of guanidinoacetate (GAA) in the brain increases in guanidino acetate methyl transferase (GAMT) deficiency, an inherited…”
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Activation of cerebellar granule cells GABAA receptors by guanidinoacetate by Cupello, A, Balestrino, M, Gatta, E, Pellistri, F, Siano, S, Robello, M

“…Abstract The extracellular concentration of guanidinoacetate (GAA) in the brain increases in guanidino acetate methyl transferase (GAMT) deficiency, an…”
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Binding of Paroxetine to the Serotonin Transporter in Membranes from Different Cells, Subcellular Fractions and Species by Cupello, A., Albano, C., Gatta, E., Scarrone, S., Villa, E., Zona, G.

“…The binding of [ 3 H]-paroxetine to membrane serotonin transporter (SERT) has been studied in membranes from different sources and subcellular fractions. From…”
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Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage by Balestrino, M, Lensman, M, Parodi, M, Perasso, L, Rebaudo, R, Melani, R, Polenov, S, Cupello, A

“…Phosphocreatine can to some extent compensate for the lack of ATP synthesis that is caused in the brain by deprivation of oxygen or glucose. Treatment of in…”
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NITRIC OXIDE AND GABA A RECEPTOR FUNCTION THE RAT CEREBRAL CORTEX AND CEREBELLAR GRANULE CELLS by ROBELLO, M., AMICO, C., BUCOSSI, G., CUPELLO, A., RAPALLINO, M.V., THELLUNG, S.

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Abnormalities of Na/K ATPase in migraine with aura by Scarrone, S, Podestà, M, Cupello, A, Finocchi, C, Frassoni, F, Gandolfo, C, Balestrino, M

“…It has been previously shown from our laboratory that abnormal functioning of Na/K ATPase can cause spreading depression, the likely mechanism of migraine…”
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Immunocytochemical study by two photon fluorescence microscopy of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture by Merlo, F, Balduzzi, R, Cupello, A, Robello, M

“…An immunocytochemical investigation of the expression of α₁, α₆, β₂/₃, γ₂and δ subunits was performed on rat cerebellum granule cells in culture by the two…”
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Involvement of phosphatase activities in the run-down of GABA A receptor function in rat cerebellar granule cells in culture by Amico, C, Cupello, A, Fossati, C, Robello, M

“…Run-down of GABA activated Cl − currents was found when rat cerebellar granule cells in culture were studied by the whole-cell patch-clamp technique in the…”
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Calcium accumulation in neurites and cell bodies of rat cerebellar granule cells in culture: effects on GABAA receptor function by Cupello, A., Esposito, A., Marchetti, C., Pellistri, F., Robello, M.

“…Issue Title: Special Issue: Neurodegeneration, Neurotoxicity and Metabolic Insults Provoked by Amino Acids Accumulation of calcium in rat cerebellar granule…”
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Nitric oxide and GABAA receptor function in the rat cerebral cortex and cerebellar granule cells by ROBELLO, M, AMICO, C, BUCOSSI, G, CUPELLO, A, RAPALLINO, M. V, THELLUNG, S

“…The aim of the present work was to investigate the mechanism by which the diffusible factor nitric oxide regulates GABAA receptor function in the brain. The…”
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