Search Results - "Cuollo, Lorenzo"

The Senescence-Associated Secretory Phenotype (SASP) in the Challenging Future of Cancer Therapy and Age-Related Diseases by Cuollo, Lorenzo, Antonangeli, Fabrizio, Santoni, Angela, Soriani, Alessandra

“…Cellular senescence represents a robust tumor-protecting mechanism that halts the proliferation of stressed or premalignant cells. However, this state of…”
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Doxorubicin-Mediated miR-433 Expression on Exosomes Promotes Bystander Senescence in Multiple Myeloma Cells in a DDR-Independent Manner by Vulpis, Elisabetta, Cuollo, Lorenzo, Borrelli, Cristiana, Antonangeli, Fabrizio, Masuelli, Laura, Cippitelli, Marco, Fionda, Cinzia, Caracciolo, Giulio, Petrucci, Maria Teresa, Santoni, Angela, Zingoni, Alessandra, Soriani, Alessandra

“…The success of senescence-based anticancer therapies relies on their anti-proliferative power and on their ability to trigger anti-tumor immune responses…”
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NEDD8-activating enzyme inhibition potentiates the anti-myeloma activity of natural killer cells by Petillo, Sara, Sproviero, Elena, Loconte, Luisa, Cuollo, Lorenzo, Zingoni, Alessandra, Molfetta, Rosa, Fionda, Cinzia, Soriani, Alessandra, Cerboni, Cristina, Petrucci, Maria Teresa, Fazio, Francesca, Paolini, Rossella, Santoni, Angela, Cippitelli, Marco

“…Natural Killer (NK) cells act as important regulators in the development and progression of hematological malignancies and their suppressor activity against…”
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CD38 restrains the activity of extracellular cGAMP in a model of multiple myeloma by Cuollo, Lorenzo, Di Cristofano, Samuele, Sandomenico, Annamaria, Iaccarino, Emanuela, Oliver, Angela, Zingoni, Alessandra, Cippitelli, Marco, Fionda, Cinzia, Petillo, Sara, Kosta, Andrea, Tassinari, Valentina, Petrucci, Maria Teresa, Fazio, Francesca, Ruvo, Menotti, Santoni, Angela, Raimondo, Domenico, Soriani, Alessandra

“…2′3′-cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) is the endogenous agonist of STING; as such, cGAMP has powerful immunostimulatory activity,…”
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Cancer extracellular vesicles as novel regulators of NK cell response by Soriani, Alessandra, Vulpis, Elisabetta, Cuollo, Lorenzo, Santoni, Angela, Zingoni, Alessandra

“…[Display omitted] •NK cells are critical players in tumour immune surveillance.•Extracellular vesicles are important mediators of tumour cell-to-cell…”
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Neutrophil-activating secretome characterizes palbociclib-induced senescence of breast cancer cells by Favaretto, Gabriele, Rossi, Marianna Nicoletta, Cuollo, Lorenzo, Laffranchi, Mattia, Cervelli, Manuela, Soriani, Alessandra, Sozzani, Silvano, Santoni, Angela, Antonangeli, Fabrizio

“…Senescent cells have a profound impact on the surrounding microenvironment through the secretion of numerous bioactive molecules and inflammatory factors. The…”
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