Search Results - "Cunyat, Francesc"
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Frontline Science: HIV infection of Kupffer cells results in an amplified proinflammatory response to LPS
Published in Journal of leukocyte biology (01-05-2017)“…HIV‐1 infection of KCs leads to dysregulated innate immune response to LPS, and may play a role in hepatic inflammation and fibrosis. End‐stage liver disease…”
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T-Follicular-Like CD8 + T Cell Responses in Chronic HIV Infection Are Associated With Virus Control and Antibody Isotype Switching to IgG
Published in Frontiers in immunology (15-06-2022)“…T cell responses are considered critical for the control of HIV, but the contribution of different T cell subsets to this control remains unclear. Using a…”
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Functional analyses reveal extensive RRE plasticity in primary HIV-1 sequences selected under selective pressure
Published in PloS one (29-08-2014)“…HIV-1 Rev response element (RRE) is a functional region of viral RNA lying immediately downstream to the junction of gp120 and gp41 in the env coding sequence…”
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Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection
Published in PloS one (16-05-2012)“…Xenotropic murine leukemia virus-related virus (XMRV) was generated after a recombination event between two endogenous murine leukemia viruses during the…”
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The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype
Published in Retrovirology (14-02-2012)“…Resistance to the fusion inhibitor enfuvirtide (ENF) is achieved by changes in the gp41 subunit of the HIV envelope glycoprotein (Env). Specific ENF-associated…”
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Colony-Stimulating Factor 1 Receptor Antagonists Sensitize Human Immunodeficiency Virus Type 1-Infected Macrophages to TRAIL-Mediated Killing
Published in Journal of virology (15-07-2016)“…Strategies aimed at eliminating persistent viral reservoirs from HIV-1-infected individuals have focused on CD4(+) T-cell reservoirs. However, very little…”
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Production and characterization of novel Anti-HIV Fc-fusion proteins in plant-based systems: Nicotiana benthamiana & tobacco BY-2 cell suspension
Published in New biotechnology (25-11-2024)“…Multifunctional anti-HIV Fc-fusion proteins aim to tackle HIV efficiently through multiple modes of action. Although results have been promising, these…”
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Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8+ T Cell Killing
Published in Journal of virology (01-10-2015)“…Simian immunodeficiency virus (SIV)-specific CD8(+) T cells kill SIV-infected CD4(+) T cells in an major histocompatibility complex class I (MHC-I)-dependent…”
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Evaluation of the cytopathicity (fusion/hemifusion) of patient-derived HIV-1 envelope glycoproteins comparing two effector cell lines
Published in Journal of biomolecular screening (01-07-2012)“…HIV-1 envelope glycoprotein (Env) is a major determinant of viral pathogenicity. The evaluation of the biological properties of patient-derived envelopes by…”
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Susceptibility of Human Lymphoid Tissue Cultured ex vivo to Xenotropic Murine Leukemia Virus-Related Virus
Published in PloS one (16-05-2012)“…Background: Xenotropic murine leukemia virus-related virus (XMRV) was generated after a recombination event between two endogenous murine leukemia viruses…”
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Genotypic and phenotypic evolution of HIV type-1 protease during in vitro sequential or concomitant combination of atazanavir and amprenavir
Published in Antiviral therapy (01-01-2010)“…The pathways of resistance to atazanavir (ATV) and amprenavir (APV) converge at position 50 of HIV protease. The determinants of cross-resistance were analysed…”
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