Search Results - "Cuntai Zhang"

Pre-emptive pharmacological inhibition of fatty acid–binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism by Chen, Yuting, Dai, Yue, Song, Kaixin, Huang, Yi, Zhang, Le, Zhang, Cuntai, Yan, Qi, Gao, Hongyu

“…Kidney fibrosis is a hallmark of chronic kidney disease (CKD) progression that is caused by tubular injury and dysregulated lipid metabolism. Genetic abolition…”
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Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis by Chen, Yuting, Yan, Qi, Lv, Mengyue, Song, Kaixin, Dai, Yue, Huang, Yi, Zhang, Le, Zhang, Cuntai, Gao, Hongyu

“…Following a chronic insult, renal tubular epithelial cells (TECs) contribute to the development of kidney fibrosis through dysregulated lipid metabolism that…”
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Identification and validation of a copper homeostasis-related gene signature for the predicting prognosis of breast cancer patients via integrated bioinformatics analysis by Li, Yi, Wei, Xiuxian, Wang, Yuning, Wang, Wenzhuo, Zhang, Cuntai, Kong, Deguang, Liu, Yu

“…The prognostic value of copper homeostasis-related genes in breast cancer (BC) remains largely unexplored. We analyzed copper homeostasis-related gene profiles…”
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The DACH/EYA/SIX gene network and its role in tumor initiation and progression by Liu, Yu, Han, Na, Zhou, Si, Zhou, Rong, Yuan, Xun, Xu, Hanxiao, Zhang, Cuntai, Yin, Tiejun, Wu, Kongming

“…The functional abnormality of developmental genes is a common phenomenon in cancer initiation and progression. The retinal determination gene network (RDGN) is…”
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Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction by Cheng, Mian, Wu, Gang, Song, Yue, Wang, Lin, Tu, Ling, Zhang, Lizhi, Zhang, Cuntai

“…Abstract Backgroud: Myocardial fibrosis results in myocardial remodelling and dysfunction. Celastrol, a traditional oriental medicine, has been suggested to…”
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Associations between the geriatric nutritional risk index and the risk of and mortality associated with chronic kidney disease in older individuals by Zou, Peilin, Zhang, Yucong, Chen, Liangkai, Liu, Man, Nie, Hao, Gao, Hongyu, Zhang, Cuntai, Yan, Jinhua

“…Malnutrition is a complication of chronic kidney disease (CKD). Whether malnutrition, assessed via the geriatric nutritional risk index (GNRI), is associated…”
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Hypertension, sleep quality, depression, and cognitive function in elderly: A cross-sectional study by Chen, Jiajie, Chen, Xi, Mao, Ruxue, Fu, Yu, Chen, Qin, Zhang, Cuntai, Zheng, Kai

“…Hypertension, sleep disorders, and depression are highly prevalent in the elderly population and are all associated with cognitive impairment, but the role…”
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Bazedoxifene exhibits growth suppressive activity by targeting interleukin‐6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma by Ma, Haiyan, Yan, Dan, Wang, Yina, Shi, Wei, Liu, Tianshu, Zhao, Chongqiang, Huo, Shengqi, Duan, Jialin, Tao, Jingwen, Zhai, Maocai, Luo, Pengcheng, Guo, Junyi, Tian, Lei, Mageta, Lulu, Jou, David, Zhang, Cuntai, Li, Chenglong, Lin, Jiayuh, Lv, Jiagao, Li, Sheng, Lin, Li

“…The interleukin (IL)‐6/glycoprotein (GP)130/signal transducer and activator of transcription (STAT)3 pathway is emerging as a target for the treatment of…”
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Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects by Wang, Siyuan, Wang, Jiaxin, Xia, Yu, Zhang, Le, Jiang, Yueqiang, Liu, Man, Gao, Qinglei, Zhang, Cuntai

“…Immune checkpoint blockades have been prized in circumventing and ablating the impediments posed by immunosuppressive receptors, reaching an exciting juncture…”
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Overview of Innate Immune Cell Landscape in Liver Aging by Lin, Yan, Li, Qiao, Liang, Guangyu, Xiao, Nanyin, Yang, Jiankun, Yang, Xiao, Zhang, Heng, Zhang, Cuntai, Liu, Anding

“…Aging is a biological process with a gradual decline in functional capacity, and this process often enhances the risk of chronic disease morbidity and…”
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Metabolic clues to aging: exploring the role of circulating metabolites in frailty, sarcopenia and vascular aging related traits and diseases by Qian, Zonghao, Huang, Yuzhen, Zhang, Yucong, Yang, Ni, Fang, Ziwei, Zhang, Cuntai, Zhang, Le

“…Physical weakness and cardiovascular risk increase significantly with age, but the underlying biological mechanisms remain largely unknown. This study aims to…”
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Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy by Liu, Anding, Guo, Enshuang, Yang, Jiankun, Yang, Yan, Liu, Shenpei, Jiang, Xiaojing, Hu, Qi, Dirsch, Olaf, Dahmen, Uta, Zhang, Cuntai, Gewirtz, David A, Fang, Haoshu

“…Summary Recent studies showing the therapeutic effect of young blood on aging‐associated deterioration of organs point to young blood as the solution for…”
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Physical frailty, genetic predisposition, and incident arrhythmias by Zhang, Yucong, Liu, Man, Li, Jiajun, Ruan, Lei, Wu, Xiaofen, Zhang, Cuntai, Chen, Liangkai

“…Background Cross‐sectional evidence suggests a possible link between frailty and atrial fibrillation (AF). It remains unclear whether frailty and incident…”
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The essential role of dual-energy x-ray absorptiometry in the prediction of subclinical cardiovascular disease by Yang, Sisi, Chen, Qin, Fan, Yang, Zhang, Cuntai, Cao, Ming

“…Subclinical cardiovascular disease (Sub-CVD) is an early stage of cardiovascular disease and is often asymptomatic. Risk factors, including hypertension,…”
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miR-4456/CCL3/CCR5 Pathway in the Pathogenesis of Tight Junction Impairment in Chronic Obstructive Pulmonary Disease by Yu, Weiwei, Ye, Ting, Ding, Jie, Huang, Yi, Peng, Yang, Xia, Qin, Cuntai, Zhang

“…Cigarette smoke exposure (CSE) is a major cause of chronic obstructive pulmonary disease (COPD). The smoke disrupts cell-cell adhesion by inducing epithelial…”
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Chinese expert consensus on antithrombotic management of high‐risk elderly patients with chronic coronary syndrome by Zhang, Cuntai, Wang, Xiaoming

“…The prevalence and mortality of coronary artery disease (CAD) in China are still at an increasing stage. CAD can be classified as acute coronary syndrome (ACS)…”
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The expression profile and clinic significance of the SIX family in non-small cell lung cancer by Liu, Qian, Li, Anping, Tian, Yijun, Liu, Yu, Li, Tengfei, Zhang, Cuntai, Wu, Jennifer D, Han, Xinwei, Wu, Kongming

“…The SIX family homeobox genes have been demonstrated to be involved in the tumor initiation and progression, but their clinicopathological features and…”
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Association between Life's Essential 8 and estimated pulse wave velocity among adults in the US: a cross-sectional study of NHANES 2011-2018 by Fan, Yang, Yang, Sisi, Ruan, Lei, Zhang, Cuntai, Cao, Ming

“…Arterial stiffness, typically evaluated via estimated pulse wave velocity (ePWV), is believed to have a significant association with cardiovascular diseases…”
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Ferroptosis in age-related vascular diseases: Molecular mechanisms and innovative therapeutic strategies by Dai, Yue, Wei, Xiuxian, Jiang, Tao, Wang, Qian, Li, Yi, Ruan, Nan, Luo, Pengcheng, Huang, Jingwen, Yang, Yan, Yan, Qi, Zhang, Cuntai, Liu, Yu

“…Aging, an inevitable aspect of human existence, serves as one of the predominant risk factors for vascular diseases. Delving into the mystery of vascular…”
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Longitudinal association between cardiovascular health and arterial stiffness in the Chinese adult population by Sang, Yu, Mao, Kaimin, Cao, Ming, Wu, Xiaofen, Ruan, Lei, Zhang, Cuntai

“…Objective Arterial stiffness may be an intermediary biological pathway involved in the association between cardiovascular health (CVH) and cardiovascular…”
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