Search Results - "Cunningham, Paul K"
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Projected changes in Brook Trout and Brown Trout distribution in Wisconsin streams in the mid-twenty-first century in response to climate change
Published in Hydrobiologia (01-09-2019)“…Climate warming is a threat to the survival of fishes adapted to cold water. Brook Trout Salvelinus fontinalis and Brown Trout Salmo trutta are two cold-water…”
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THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS
Published in Drug metabolism and disposition (01-02-2004)“…The absorption, metabolism, and excretion of [ 14 C]aprepitant, a potent and selective human substance P receptor antagonist for the treatment of…”
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Lymphatic absorption, metabolism, and excretion of a therapeutic peptide in dogs and rats
Published in Drug metabolism and disposition (01-12-2013)“…The objective of the current study was to evaluate the mechanism of absorption and metabolism of a PEGylated peptide, MRL-1 (46 kDa), after s.c. dosing in dogs…”
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A Potent, Orally Bioavailable Benzazepinone Growth Hormone Secretagogue
Published in Journal of medicinal chemistry (07-05-1998)“…The identification of L-739,943 (8b), a potent, orally bioavailable benzolactam growth hormone secretagogue, is obtained from zwitterionic L-692,429 through…”
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Cannabinoid-1 receptor inhibition prevents the reduction of 24-hour energy expenditure with weight loss
Published in Metabolism, clinical and experimental (01-04-2012)“…Abstract Pharmacologic inhibition of the cannabinoid-1 receptor (CB1R) in rodent models leads to weight loss and time-dependent changes in energy balance. This…”
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In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia
Published in American journal of veterinary research (01-07-2005)“…To determine cyclooxygenase (COX)-2 selectivity, pharmacokinetic properties, and in vivo efficacy of firocoxib (ML-1,785,713) in cats. 5 healthy male and 14…”
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