Search Results - "Cunningham, Melissa"
-
1
HPV vaccine acceptability in Africa: A systematic review
Published in Preventive medicine (01-12-2014)“…Abstract Objective The objective of this study was to provide a systematic review of peer-reviewed literature on the factors associated with HPV vaccine…”
Get full text
Journal Article -
2
Contributions of the Department of Defense Congressionally Directed Medical Research Programs to Advances in Cancer Therapeutics
Published in Military medicine (22-07-2023)“…ABSTRACT Nearly a billion dollars is spent annually in the Military Health System (MHS) on cancer diagnosis and treatment, with a large portion of that…”
Get full text
Journal Article -
3
Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland
Published in Cancer research (Chicago, Ill.) (01-02-2011)“…Expression of the c-Myc oncoprotein is affected by conserved threonine 58 (T58) and serine 62 (S62) phosphorylation sites that help to regulate c-Myc protein…”
Get full text
Journal Article -
4
-
5
Cervical cancer screening and HPV vaccine acceptability among rural and urban women in Kilimanjaro Region, Tanzania
Published in BMJ open (10-03-2015)“…Objective To determine cervical cancer screening coverage and the knowledge, attitudes and barriers toward screening tests among women in rural and urban areas…”
Get full text
Journal Article -
6
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus
Published in Immunology (01-11-2022)“…Oestrogen and oestrogen receptor alpha (ERα) have been implicated in systemic lupus erythematosus pathogenesis. ERα signalling influences dendritic cell (DC)…”
Get full text
Journal Article -
7
TLR7 Agonism Accelerates Disease and Causes a Fatal Myeloproliferative Disorder in NZM 2410 Lupus Mice
Published in Frontiers in immunology (10-01-2020)“…Murine models of lupus, both spontaneous and inducible, are valuable instruments to study SLE pathogenesis. Accelerants such as Type I IFN are often used to…”
Get full text
Journal Article -
8
1004 Altered ERα localization differentially modulates immune cell subsets
Published in Lupus science & medicine (14-12-2022)“…BackgroundEstrogen is anti- or pro-inflammatory depending on milieu and plays a role in the increased incidence of lupus in reproductive age women. Estrogen’s…”
Get full text
Journal Article -
9
Distinct genome-wide DNA methylation and gene expression signatures in classical monocytes from African American patients with systemic sclerosis
Published in Clinical epigenetics (17-02-2023)“…Systemic sclerosis (SSc) is a multisystem autoimmune disorder that has an unclear etiology and disproportionately affects women and African Americans. Despite…”
Get full text
Journal Article -
10
Complete knockout of estrogen receptor alpha is not directly protective in murine lupus
Published in Clinical immunology (Orlando, Fla.) (01-10-2017)“…Systemic lupus erythematosus (SLE) is a chronic and potentially severe autoimmune disease that disproportionately affects women. Despite a known role for…”
Get full text
Journal Article -
11
Optimal management of fatigue in patients with systemic lupus erythematosus: a systematic review
Published in Therapeutics and clinical risk management (01-01-2014)“…Among the host of distressing pathophysiological and psychosocial symptoms, fatigue is the most prevalent complaint in patients with systemic lupus…”
Get full text
Journal Article -
12
Racial Differences in Plasma Microbial Translocation and Plasma Microbiome, Implications in Systemic Lupus Erythematosus Disease Pathogenesis
Published in ACR open rheumatology (01-06-2024)“…Objective Black groups have increased prevalence and accelerated pathogenicity of systemic lupus erythematosus (SLE) compared to other ethnic/racial groups…”
Get full text
Journal Article -
13
Early Ovariectomy Results in Reduced Numbers of CD11c+/CD11b+ Spleen Cells and Impacts Disease Expression in Murine Lupus
Published in Frontiers in immunology (15-02-2016)“…Ninety percent of those diagnosed with systemic lupus erythematosus are female, with peak incidence between the ages of 15 and 45, when women are most…”
Get full text
Journal Article -
14
Wapl antagonizes cohesin binding and promotes Polycomb-group silencing in Drosophila
Published in Development (Cambridge) (15-11-2012)“…Wapl protein regulates binding of the cohesin complex to chromosomes during interphase and helps remove cohesin from chromosomes at mitosis. We isolated a…”
Get full text
Journal Article -
15
Novel mechanism for estrogen receptor alpha modulation of murine lupus
Published in Journal of autoimmunity (01-02-2019)“…Female sex is a risk factor for lupus. Sex hormones, sex chromosomes and hormone receptors are implicated in the pathogenic pathways in lupus. Estrogen…”
Get full text
Journal Article -
16
Plasmacytoid dendritic cell distribution and maturation are altered in lupus prone mice prior to the onset of clinical disease
Published in Clinical immunology (Orlando, Fla.) (01-02-2017)“…Abstract Plasmacytoid dendritic cells (pDCs) and their production of type I interferons (IFN) are key pathogenic mediators of systemic lupus erythematosus…”
Get full text
Journal Article -
17
Development and implementation of a virtual Lupus Patient Education Event during the COVID-19 pandemic
Published in Lupus science & medicine (10-03-2021)“…Patient education interventions decrease hospitalisations, reduce visits to emergency departments and improve patient quality of life.1–3 Patient education is…”
Get full text
Journal Article -
18
Estrogen Receptor α Deficiency Modulates TLR Ligand-Mediated PDC-TREM Expression in Plasmacytoid Dendritic Cells in Lupus-Prone Mice
Published in The Journal of immunology (1950) (15-12-2015)“…Female lupus-prone NZM2410 estrogen receptor α (ERα)-deficient mice are protected from renal disease and have prolonged survival compared with wild-type…”
Get full text
Journal Article -
19
A Valid and Reliable Assessment Tool for Remote Simulation-Based Ultrasound-Guided Regional Anesthesia
Published in Regional anesthesia and pain medicine (01-11-2014)“…BACKGROUND AND OBJECTIVESThe purpose of this study was to establish construct and concurrent validity and interrater reliability of an assessment tool for…”
Get full text
Journal Article -
20
A case of Rowell syndrome with excellent improvement following anifrolumab
Published in JAAD Case Reports (01-01-2023)Get full text
Journal Article