Search Results - "Cuneo, Kyle"

Role of Stereotactic Body Radiation Therapy in Oligometastatic Sarcoma by Cuneo, Kyle C.

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High-Performance Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry for Exosome Metabolomics by Luo, Xian, An, Mingrui, Cuneo, Kyle C, Lubman, David M, Li, Liang

“…Circulating exosomes in bodily fluids such as blood are being actively studied as a rich source of chemical biomarkers for cancer diagnosis and monitoring…”
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Stereotactic Body Radiation Therapy as an Alternative to Transarterial Chemoembolization for Hepatocellular Carcinoma by Sapir, Eli, Tao, Yebin, Schipper, Matthew J., Bazzi, Latifa, Novelli, Paula M., Devlin, Pauline, Owen, Dawn, Cuneo, Kyle C., Lawrence, Theodore S., Parikh, Neehar D., Feng, Mary

“…To conduct a large single-institution comparison of transarterial chemoembolization (TACE) and stereotactic body radiation therapy (SBRT) outcomes in similar…”
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Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer by Cuneo, Kyle C, Morgan, Meredith A, Sahai, Vaibhav, Schipper, Matthew J, Parsels, Leslie A, Parsels, Joshua D, Devasia, Theresa, Al-Hawaray, Mahmoud, Cho, Clifford S, Nathan, Hari, Maybaum, Jonathan, Zalupski, Mark M, Lawrence, Theodore S

“…AZD1775 (adavosertib) is an inhibitor of the Wee1 kinase. In this study, we built on our preclinical studies to evaluate the safety and efficacy of AZD1775 in…”
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PD-L1 Expression in Circulating Tumor Cells Increases during Radio(chemo)therapy and Indicates Poor Prognosis in Non-small Cell Lung Cancer by Wang, Yang, Kim, Tae Hyun, Fouladdel, Shamileh, Zhang, Zhuo, Soni, Payal, Qin, Angel, Zhao, Lili, Azizi, Ebrahim, Lawrence, Theodore S., Ramnath, Nithya, Cuneo, Kyle C., Nagrath, Sunitha

“…Preclinical studies demonstrated that radiation up-regulates PD-L1 expression in tumor cells, providing a rationale for combining PD-1/PD-L1 inhibitors with…”
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Quantitative Proteomic Analysis of Serum Exosomes from Patients with Locally Advanced Pancreatic Cancer Undergoing Chemoradiotherapy by An, Mingrui, Lohse, Ines, Tan, Zhijing, Zhu, Jianhui, Wu, Jing, Kurapati, Himabindu, Morgan, Meredith A, Lawrence, Theodore S, Cuneo, Kyle C, Lubman, David M

“…Pancreatic cancer is the third leading cause of cancer-related death in the USA. Despite extensive research, minimal improvements in patient outcomes have been…”
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Comparison of Stereotactic Body Radiation Therapy and Radiofrequency Ablation in the Treatment of Intrahepatic Metastases by Jackson, William C., Tao, Yebin, Mendiratta-Lala, Mishal, Bazzi, Latifa, Wahl, Dan R., Schipper, Matthew J., Feng, Mary, Cuneo, Kyle C., Lawrence, Theodore S., Owen, Dawn

“…Stereotactic body radiation therapy (SBRT) and radiofrequency ablation (RFA) are widely used therapies for the treatment of intrahepatic metastases; however,…”
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A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer by Whitley, Melodi Javid, Cardona, Diana M, Lazarides, Alexander L, Spasojevic, Ivan, Ferrer, Jorge M, Cahill, Joan, Lee, Chang-Lung, Snuderl, Matija, Blazer, 3rd, Dan G, Hwang, E Shelley, Greenup, Rachel A, Mosca, Paul J, Mito, Jeffrey K, Cuneo, Kyle C, Larrier, Nicole A, O'Reilly, Erin K, Riedel, Richard F, Eward, William C, Strasfeld, David B, Fukumura, Dai, Jain, Rakesh K, Lee, W David, Griffith, Linda G, Bawendi, Moungi G, Kirsch, David G, Brigman, Brian E

“…Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic residual cancer in the tumor…”
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Imaging Findings Within the First 12 Months of Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy by Mendiratta-Lala, Mishal, Gu, Everett, Owen, Dawn, Cuneo, Kyle C., Bazzi, Latifa, Lawrence, Theodore S., Hussain, Hero K., Davenport, Matthew S.

“…To correlate the imaging findings of treated hepatocellular carcinoma (HCC) after stereotactic body radiation therapy (SBRT) with explant pathology and…”
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Advances in Radiation Therapy for Primary Liver Cancer by Cuneo, Kyle C., Herr, Daniel J.

“…During the past 30 years, several advances have been made allowing for safer and more effective treatment of patients with liver cancer. This report reviews…”
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Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress by Cuneo, Kyle C., MD, Morgan, Meredith A., PhD, Davis, Mary A., PhD, Parcels, Leslie A., PhD, Parcels, Joshua, BS, Karnak, David, PhD, Ryan, Caila, Liu, Na, BS, Maybaum, Jonathan, PhD, Lawrence, Theodore S., MD, PhD

“…Purpose Wee1 kinase inhibitors are effective radiosensitizers in cells lacking a G1 checkpoint. In this study we examined the potential effect of Wee1 kinase…”
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Safety and Efficacy of Stereotactic Radiosurgery and Adjuvant Bevacizumab in Patients With Recurrent Malignant Gliomas by Cuneo, Kyle C., M.D, Vredenburgh, James J., M.D, Sampson, John H., M.D., Ph.D, Reardon, David A., M.D, Desjardins, Annick, M.D, Peters, Katherine B., M.D., Ph.D, Friedman, Henry S., M.D, Willett, Christopher G., M.D, Kirkpatrick, John P., M.D., Ph.D

“…Purpose Patients with recurrent malignant gliomas treated with stereotactic radiosurgery (SRS) and multiagent systemic therapies were reviewed to determine the…”
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EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection by Cuneo, Kyle C, Nyati, Mukesh K, Ray, Dipankar, Lawrence, Theodore S

“…The epidermal growth factor receptor (EGFR) plays an important role in tumor progression and treatment resistance for many types of malignancies including head…”
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Long term outcomes of stereotactic body radiation therapy for hepatocellular carcinoma without macrovascular invasion by Mathew, Ashwathy Susan, Atenafu, Eshetu G., Owen, Dawn, Maurino, Chris, Brade, Anthony, Brierley, James, Dinniwell, Robert, Kim, John, Cho, Charles, Ringash, Jolie, Wong, Rebecca, Cuneo, Kyle, Feng, Mary, Lawrence, Theodore S., Dawson, Laura A.

“…Stereotactic Body Radiation Therapy (SBRT) is a non-invasive ablative treatment for hepatocellular carcinoma (HCC). This report aimed to address the limited…”
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Real-time, volumetric imaging of radiation dose delivery deep into the liver during cancer treatment by Zhang, Wei, Oraiqat, Ibrahim, Litzenberg, Dale, Chang, Kai-Wei, Hadley, Scott, Sunbul, Noora Ba, Matuszak, Martha M., Tichacek, Christopher J., Moros, Eduardo G., Carson, Paul L., Cuneo, Kyle C., Wang, Xueding, El Naqa, Issam

“…Ionizing radiation acoustic imaging (iRAI) allows online monitoring of radiation’s interactions with tissues during radiation therapy, providing real-time,…”
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Drug-Radiotherapy Combination Trial Developments-Letter by Evans, Joseph R, Cuneo, Kyle C, Lawrence, Theodore S

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Treatment of Locally Recurrent Rectal Cancer: A Review by Regan, Samuel N, Hendren, Samantha, Krauss, John C, Crysler, Oxana V, Cuneo, Kyle C

“…Up to 10% of patients with locally advanced rectal cancer will experience locoregional recurrence. In the setting of prior surgery and often radiation and…”
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Magnetic Resonance Imaging Evaluation of Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy: Long Term Imaging Follow-Up by Mendiratta-Lala, Mishal, Masch, William, Shankar, Prasad R., Hartman, Holly E., Davenport, Matthew S., Schipper, Matthew J., Maurino, Chris, Cuneo, Kyle C., Lawrence, Theodore S., Owen, Dawn

“…To determine the natural history of imaging findings seen on magnetic resonance imaging (MRI) of hepatocellular carcinoma (HCC) treated with stereotactic body…”
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Is Apparent Diffusion Coefficient Established as an Imaging Biomarker for Stereotactic Body Radiation Therapy Assessment in Hepatocellular Carcinoma? by Cao, Yue, Cuneo, Kyle C., Evans, Joseph, Ten Haken, Randall K., Chang, Daniel T., Lawrence, Theodore S.

“…In this article, as part of this special issue on biomarkers of early response, we review currently available reports regarding magnetic resonance imaging…”
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Concurrent Stereotactic Radiosurgery and Bevacizumab in Recurrent Malignant Gliomas: A Prospective Trial by Cabrera, Alvin R., MD, Cuneo, Kyle C., MD, Desjardins, Annick, MD, Sampson, John H., MD, PhD, McSherry, Frances, MA, Herndon, James E., PhD, Peters, Katherine B., MD, PhD, Allen, Karen, ANP, Hoang, Jenny K., MBBS, Chang, Zheng, PhD, Craciunescu, Oana, PhD, Vredenburgh, James J., MD, Friedman, Henry S., MD, Kirkpatrick, John P., MD, PhD

“…Purpose Virtually all patients with malignant glioma (MG) eventually recur. This study evaluates the safety of concurrent stereotactic radiosurgery (SRS) and…”
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