Search Results - "Cundiff, Deborah L"

Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model by Hobbs, Jennifer E, Zakarija, Anaadriana, Cundiff, Deborah L, Doll, Jennifer A, Hymen, Emily, Cornwell, Mona, Crawford, Susan E, Liu, Na, Signaevsky, Maxim, Soff, Gerald A

“…Abstract Introduction Tissue Factor (TF) expression is observed in many types of cancer, associated with more aggressive disease, and thrombosis…”
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Venous thromboembolic disease in users of low-estrogen combined estrogen-progestin oral contraceptives by Sidney, Stephen, Petitti, Diana B, Soff, Gerald A, Cundiff, Deborah L, Tolan, Kimberly K, Quesenberry, Charles P

“…To assess the relationship between venous thromboembolic disease (VTE) and use of low-estrogen dose (<50 μg) combined estrogen-progestin oral contraceptives…”
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The Mechanism of Cancer-Mediated Conversion of Plasminogen to the Angiogenesis Inhibitor Angiostatin by Gately, Stephen, Twardowski, Przemyslaw, Stack, M. Sharon, Cundiff, Deborah L., Grella, Davida, Castellino, Francis J., Enghild, Jan, Kwaan, Hau C., Lee, Francis, Kramer, Robert A., Volpert, Olga, Bouck, Noel, Soff, Gerald A.

“…Angiostatin, a potent naturally occurring inhibitor of angiogenesis and growth of tumor metastases, is generated by cancer-mediated proteolysis of plasminogen…”
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In vivo Generation of Angiostatin Isoforms by Administration of a Plasminogen Activator and a Free Sulfhydryl Donor: A Phase I Study of an Angiostatic Cocktail of Tissue Plasminogen Activator and Mesna by SOFF, Gerald A, HAO WANG, CUNDIFF, Deborah L, KEYI JIANG, MARTONE, Brenda, RADEMAKER, Alfred W, DOLL, Jennifer A, KUZEL, Timothy M

“…Purpose: Angiostatin 4.5 (AS4.5), the endogenous human angiostatin, is derived from plasminogen in a two-step process. A plasminogen activator converts…”
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Differential binding of plasminogen, plasmin, and angiostatin4.5 to cell surface β-actin : Implications for cancer-mediated angiogenesis by HAO WANG, DOLL, Jennifer A, KEYI JIANG, CUNDIFF, Deborah L, CZARNECKI, Jarema S, WILSON, Mindy, RIDGE, Karen M, SOFF, Gerald A

“…Angiostatin4.5 (AS4.5) is the product of plasmin autoproteolysis and consists of kringles 1 to 4 and approximately 85% of kringle 5. In culture, cancer cell…”
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Angiostatin4.5-mediated apoptosis of vascular endothelial cells by HANFORD, Holly Anne, WONG, Christie A, KASSAN, Hallie, CUNDIFF, Deborah L, CHANDEL, Navdeep, UNDERWOOD, Suzanne, MITCHELL, Christopher A, SOFF, Gerald A

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Cell surface-dependent generation of angiostatin4.5 by HAO WANG, SCHULTZ, Ryan, HONG, Jerome, CUNDIFF, Deborah L, KEYI JIANG, SOFF, Gerald A

“…Angiostatin4.5 (AS4.5) is a naturally occurring human angiostatin isoform, consisting of plasminogen kringles 1-4 plus 85% of kringle 5 (amino acids Lys78 to…”
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Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin by GATELY, S, TWARDOWSKI, P, ENGHILD, J, KWAAN, H. C, SOFF, G. A, STACK, M. S, PATRICK, M, BOGGIO, L, CUNDIFF, D. L, SCHNAPER, H. W, MADISON, L, VOLPERT, O, BOUCK, N

“…Angiostatin is an inhibitor of angiogenesis and metastatic growth that is found in tumor-bearing animals and can be generated in vitro by the proteolytic…”
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Expression of Alternatively-Spliced Human Tissue Factor, but Not Full-Length Tissue Factor, Enhances Tumor Growth and Tumor-Associated Vasculature by Soff, Gerald A., Hobbs, Jennifer, Hyman, Emily, Cundiff, Deborah L.

“…It is well-established that cancer is associated with activation of the blood coagulation system, with associated thrombosis as a major cause of morbidity and…”
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Angiostatin(4.5)-mediated apoptosis of vascular endothelial cells by Hanford, Holly Anne, Wong, Christie A, Kassan, Hallie, Cundiff, Deborah L, Chandel, Navdeep, Underwood, Suzanne, Mitchell, Christopher A, Soff, Gerald A

“…Angiostatin, a proteolytic cleavage product of plasminogen, acts via a selective, yet poorly understood mechanism to potently inhibit angiogenesis (M. S…”
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Differential Binding of Plasminogen, Plasmin, and Angiostatin4.5 to Cell Surface β-Actin: Implications for Cancer-Mediated Angiogenesis by Soff, Gerald A., Wang, Hao, Doll, Jennifer A., Jiang, Keyi, Cundiff, Deborah L.

“…Angiostatin4.5 (AS4.5), the naturally occurring human angiostatin isoform, is the product of plasmin autoproteolysis and consists of kringles 1 to 4 and ~85%…”
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Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP by Soff, G A, Cornwell, T L, Cundiff, D L, Gately, S, Lincoln, T M

“…A key component of the nitric oxide-cyclic guanosine monophosphate (cGMP) pathway in smooth muscle cells (SMC) is the type I GMP-dependent protein kinase (PK-G…”
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139 The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin by Gately, Stephen, Twardowski, Przemyslaw, Sharon Stack, M., Cundiff, Deborah L., Grella, Davida, Castellino, Francis J., Enghild, Jan, Kwaan, Hau C., Lee, Francis, Kramer, Robert A., Soff, Gerald A.

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