Search Results - "Cundari, S."

Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale by CAVALETTI, G, BOGLIUN, G, ZANNA, C, MARZORATI, L, ZINCONE, A, PIATTI, M, COLOMBO, N, PARMA, G, LISSONI, A, FEI, F, CUNDARI, S

“…The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of…”
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Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl- l-carnitine by Bianchi, Giulia, Vitali, Giordano, Caraceni, Augusto, Ravaglia, Sabrina, Capri, Giuseppe, Cundari, Sante, Zanna, Claudio, Gianni, Luca

“…Acetyl- l-carnitine (ALC) improves non-oncological neuropathies. We tested oral ALC (1 g tid) for 8 weeks in 25 patients with neuropathy grade ⩾3 (common…”
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Early predictors of peripheral neurotoxicity in cisplatin and paclitaxel combination chemotherapy by Cavaletti, G., Bogliun, G., Marzorati, L., Zincone, A., Piatti, M., Colombo, N., Franchi, D., La Presa, M. T., Lissoni, A., Buda, A., Fei, F., Cundari, S., Zanna, C.

“…Background: We investigated the possible use of clinical signs of chemotherapy-induced peripheral neurotoxicity (CIPN) or of nerve growth factor (NGF)…”
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A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy by Maestri, Antonio, De Pasquale Ceratti, Adolfo, Cundari, Sante, Zanna, Claudio, Cortesi, Enrico, Crinò, Lucio

“…In addition to bone marrow suppression and renal toxicity, neurotoxicity is a commonly occurring side effect of widely used chemotherapeutic agents like…”
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Acetyl-L-Carnitine Prevents and Reverts Experimental Chronic Neurotoxicity Induced by Oxaliplatin, Without Altering its Antitumor Properties by GHIRARDI, Orlando, LO GIUDICE, Pietro, ZANNA, Claudio, CARMINATI, Paolo, PISANO, Claudio, VERTECHY, Mario, BELLUCCI, Augusta, VESCI, Loredana, CUNDARI, Sante, MILOSO, Mariarosaria, RIGAMONTI, Laura Maria, NICOLINI, Gabriella

“…Background: Oxaliplatin (OHP) is severely neurotoxic and induces the onset of a disabling sensory peripheral neuropathy. Acetyl-L-carnitine (ALC), a natural…”
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Molecular Modeling, Synthesis, and Preliminary Biological Evaluation of Glutathione-S-Transferase Inhibitors as Potential Therapeutic Agents by Procopio, Antonio, Alcaro, Stefano, Cundari, Sante, De Nino, Antonio, Ortuso, Francesco, Sacchetta, Paolo, Pennelli, Alfonso, Sindona, Giovanni

“…Changes in the GSH/GST system have been found to correlate with resistance to anticancer alkylating agents, presumably through accelerated detoxification of…”
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Chemotherapy-induced Allodinia: Neuroprotective Effect of Acetyl-L-carnitine by Ghirardi, Orlando, Vertechy, Mario, Vesci, Loredana, Canta, Annalisa, Nicolini, Gabriella, Galbiati, Stefania, Ciogli, Cristina, Quattrini, Gianni, Pisano, Claudio, Cundari, Sante, Rigamonti, Laura Maria

“…Background: We tested the hypothesis that acetyl-L-carnitine (ALC) may have a protective and a curative role in chemotherapy-induced hyperalgesia in vivo, in…”
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Total neuropathy scale items as early predictors of chemotherapy-induced peripheral neurotoxicity by Piatti, M, Bogliun, G, Marzorati, L, Zincone, A, Giussani, G, Colombo, N, Parma, G, Lissoni, A, Fei, F, Cundari, S, Zanna, C, Cavaletti, G

“…We investigated the possible use of individual Total Neuropathy Scale (TNS) items to predict the neurological outcome in patients undergoing cisplatin and…”
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A facile one-pot synthesis of the very useful building blocks N-Boc- S-alkylatedcysteines by Cundari, Sante, Dalpozzo, Renato, De Nino, Antonio, Procopio, Antonio, Sindona, Giovanni, Athanassopulos, Kostantinos

“…A convenient one-pot method for the synthesis of N-Boc protected S-alkylcysteines, useful intermediates for the solution-phase synthesis of…”
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Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 24 by Piatti, M, Bogliun, G, Marzorati, L, Tredici, G, Villa, P, Rotondi, A, Ferraro, R, Resta, G, Fei, F, Lissoni, A, Cundari, S, Zanna, C, Cavaletti, G

“…The present study was performed with the aim to compare different clinically‐based neurotoxicity scales with a more extended composite scale (Total Neuropathy…”
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Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 25 by Piatti, M, Tagliabue, E, Tredici, G, Marmiroli, P, Zoia, C, Galbiati, S, Rigolio, R, Nicolini, G, Villa, P, Rotondi, A, Ferraro, R, Resta, G, Buda, A, Lissoni, A, Cundari, S, Zanna, C, Cavaletti, G

“…Several effective antineoplastic drugs are severely neurotoxic and induce the onset of disabling peripheral neuropathies. The clinical presentation of this…”
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